Search Results - "Ortiz Canseco, Julio"

MmpL3 Is the Cellular Target of the Antitubercular Pyrrole Derivative BM212 by LA ROSA, Valentina, POCE, Giovanna, JAVID, Babak, SORRENTINO, Flavia, LOERGER, Thomas R, SACCHETTINI, James C, MANETTI, Fabrizio, BOTTA, Maurizio, DE LOGU, Alessandro, RUBIN, Eric J, DE ROSSI, Edda, ORTIZ CANSECO, Julio, BURONI, Silvia, PASCA, Maria Rosalia, BIAVA, Mariangela, RAJU, Ravikiran M, PORRETTA, Giulio Cesare, ALFONSO, Salvatore, BATTILOCCHIO, Claudio

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

Emergence of phenotypic and genotypic antimicrobial resistance in Mycobacterium tuberculosis by Kloprogge, Frank, Ortiz Canseco, Julio, Phee, Lynette, Sadouki, Zahra, Kipper, Karin, Witney, Adam A., Stoker, Neil, McHugh, Timothy D.

“…Concentration dependency of phenotypic and genotypic isoniazid-rifampicin resistance emergence was investigated to obtain a mechanistic understanding on how…”
Get full text

Ancient and recent differences in the intrinsic susceptibility of Mycobacterium tuberculosis complex to pretomanid by Bateson, Anna, Ortiz Canseco, Julio, McHugh, Timothy D., Witney, Adam A., Feuerriegel, Silke, Merker, Matthias, Kohl, Thomas A., Utpatel, Christian, Niemann, Stefan, Andres, Sönke, Kranzer, Katharina, Maurer, Florian P, Ghodousi, Arash, Borroni, Emanuele, Cirillo, Daniela Maria, Wijkander, Maria, Toro, Juan C., Groenheit, Ramona, Werngren, Jim, Machado, Diana, Viveiros, Miguel, Warren, Robin M., Sirgel, Frederick, Dippenaar, Anzaan, Köser, Claudio U., Sun, Eugene, Timm, Juliano

“…Abstract Objectives To develop a robust phenotypic antimicrobial susceptibility testing (AST) method with a correctly set breakpoint for pretomanid (Pa), the…”
Get full text

Application of the hollow fibre infection model (HFIM) in antimicrobial development: a systematic review and recommendations of reporting by Sadouki, Zahra, McHugh, Timothy D., Aarnoutse, Rob, Ortiz Canseco, Julio, Darlow, Christopher, Hope, William, van Ingen, Jakko, Longshaw, Christopher, Manissero, Davide, Mead, Andrew, Pelligand, Ludovic, Phee, Lynette, Readman, John, Ruth, Mike M., Standing, Joseph F., Stone, Neil, Wey, Emmanuel Q., Kloprogge, Frank

“…Abstract Objectives This systematic review focuses on the use of the in vitro hollow fibre infection model (HFIM) for microbial culture. We summarize the…”
Get full text

Ertapenem and Faropenem against Mycobacterium tuberculosis: in vitro testing and comparison by macro and microdilution by Gonzalo, Ximena, Satta, Giovanni, Ortiz Canseco, Julio, McHugh, Timothy D, Drobniewski, Francis

“…Interest in carbapenems has been rising in the last few years due to the emergence of drug resistant tuberculosis. Ertapenem (ETP), given once a day…”
Get full text

Role of Whole-Genome Sequencing in Characterizing the Mechanism of Action of para -Aminosalicylic Acid and Its Resistance by Satta, Giovanni, Witney, Adam A, Begum, Neelu, Ortiz Canseco, Julio, Boa, Andrew N, McHugh, Timothy D

“…-Aminosalicylic acid (PAS) remains one of the drugs of last resort for the treatment of tuberculosis, but its mechanism of action is still not completely…”
Get full text

Glycogen synthase kinase 3 inhibition controls Mycobacterium tuberculosis infection by Peña-Díaz, Sandra, Chao, Joseph D., Rens, Celine, Haghdadi, Hasti, Zheng, Xingji, Flanagan, Keegan, Ko, Mary, Shapira, Tirosh, Richter, Adrian, Maestre-Batlle, Danay, Canseco, Julio Ortiz, Gutierrez, Maximiliano Gabriel, Duc, Khanh Dao, Pelech, Steven, Av-Gay, Yossef

“…Compounds targeting host control of infectious diseases provide an attractive alternative to antimicrobials. A phenotypic screen of a kinase library identified…”
Get full text

Epidemiological profile of multidrug-resistant and extensively drug-resistant Mycobacterium Tubrculosis among Congolese patients by Elion Assiana, Darrel Ornelle, Abdul, Jabar Babatunde Pacôme Achimi, Linguissi, Laure Stella Ghoma, Epola, Micheska, Vouvoungui, Jeannhey Christevy, Mabiala, Albert, Biyogho, Christopher Mebiame, Ronald Edoa, Jean, Adegbite, Bayodé Roméo, Adegnika, Ayola Akim, Elton, Linzy, Canseco, Julio Ortiz, McHugh, Timothy D, Ahombo, Gabriel, Ntoumi, Francine

“…There is paucity of data on the prevalence and distribution of multidrug- Resistant-Tuberculosis (MDR-TB) in the Republic of Congo. Among the challenges…”
Get full text

Unveiling the complexity of rifampicin drug susceptibility testing in Mycobacterium tuberculosis : comparative analysis with next-generation sequencing by Qadir, Mehmood, Khan, Muhammad Tahir, Khan, Sajjad Ahmed, Akram, Muhammad, Canseco, Julio Ortiz, Faryal, Rani, Wei, Dong Qing, Tahseen, Sabira

“…The discordance between phenotypic and molecular methods of rifampicin (RIF) drug susceptibility testing (DST) in poses a significant challenge, potentially…”
Get more information

Polymersomes Eradicating Intracellular Bacteria by Fenaroli, Federico, Robertson, James D, Scarpa, Edoardo, Gouveia, Virginia M, Di Guglielmo, Claudia, De Pace, Cesare, Elks, Philip M, Poma, Alessandro, Evangelopoulos, Dimitrios, Canseco, Julio Ortiz, Prajsnar, Tomasz K, Marriott, Helen M, Dockrell, David H, Foster, Simon J, McHugh, Timothy D, Renshaw, Stephen A, Martí, Josep Samitier, Battaglia, Giuseppe, Rizzello, Loris

“…Mononuclear phagocytes such as monocytes, tissue-specific macrophages, and dendritic cells are primary actors in both innate and adaptive immunity. These…”
Get full text

Epidemiological profile of multidrug-resistant and extensively drug-resistant Mycobacterium tuberculosis among Congolese patients by Elion Assiana, Darrel Ornelle, Abdul, Jabar Babatunde Pacôme Achimi, Linguissi, Laure Stella Ghoma, Epola, Micheska, Vouvoungui, Jeannhey Christevy, Mabiala, Albert, Biyogho, Christopher Mebiame, Ronald Edoa, Jean, Adegbite, Bayodé Roméo, Adegnika, Ayola Akim, Elton, Linzy, Canseco, Julio Ortiz, McHugh, Timothy D., Ahombo, Gabriel, Ntoumi, Francine

Get full text

2447. Ertapenem and Faropenem for the Treatment of Drug-Resistant Tuberculosis by Satta, Giovanni, Gonzalo, Ximena, Canseco, Julio Ortiz, Wey, Emmanuel, Drobniewski, Francis, McHugh, Timothy D

Get full text

798. The Role of Whole-Genome Sequencing in Characterizing the Mechanism of Action of Anti-Tuberculosis Compounds: Demonstrated With Para-Amino Salicylic Acid and Its Analogue by Satta, Giovanni, Witney, Adam A, Ere, Diepreye, Disney, Alex, Begum, Neelu, Canseco, Julio Ortiz, Ratledge, Colin, Boa, Andrew N, McHugh, Timothy D

Get full text