Search Results - "Ortiz, Luz E"

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  1. 1

    Identification of the Merkel Cell Polyomavirus Large Tumor Antigen Ubiquitin Conjugation Residue by Ortiz, Luz E., Pham, Alexander M., Kwun, Hyun Jin

    “…Merkel cell polyomavirus (MCPyV) large tumor (LT) antigen is a DNA binding protein essential for viral gene transcription and genome replication. MCPyV LT…”
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    Journal Article
  2. 2

    Merkel Cell Polyomavirus Large T Antigen Unique Domain Regulates Its Own Protein Stability and Cell Growth by Nwogu, Nnenna, Ortiz, Luz E, Kwun, Hyun Jin

    Published in Viruses (18-09-2020)
    “…Merkel cell polyomavirus (MCV) is the only known human oncogenic virus in the polyomaviridae family and the etiological agent of most Merkel cell carcinomas…”
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    Journal Article
  3. 3

    Therapeutic Potential of 5'-Methylschweinfurthin G in Merkel Cell Polyomavirus-Positive Merkel Cell Carcinoma by Koubek, Emily J, Weissenrieder, Jillian S, Ortiz, Luz E, Nwogu, Nnenna, Pham, Alexander M, Weissenkampen, J Dylan, Reed, Jessie L, Neighbors, Jeffrey D, Hohl, Raymond J, Kwun, Hyun Jin

    Published in Viruses (23-08-2022)
    “…Merkel cell carcinoma (MCC) is a rare but aggressive form of skin cancer predominantly caused by the human Merkel cell polyomavirus (MCPyV). Treatment for MCC…”
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    Journal Article
  4. 4

    A successful treatment with 5 methyltetrahydrofolate of a 677 TT MTHFR woman suffering premature ovarian insufficiency post a NHL (non-Hodgkin’s lymphoma) and RPL (repeat pregnancy losses) by Goyco Ortiz, Luz E., Servy, Edouard J., Menezo, Yves J. R.

    “…Methylation is an ubiquitous regulatory biochemical process in cellular physiology. It is involved in immune response, neurotransmitter function,…”
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    Journal Article
  5. 5

    Merkel Cell Polyomavirus Large T Antigen Induces Cellular Senescence for Host Growth Arrest and Viral Genome Persistence through Its Unique Domain by Pham, Alexander M, Ortiz, Luz E, Lukacher, Aron E, Kwun, Hyun Jin

    Published in Cells (Basel, Switzerland) (01-01-2023)
    “…Senescent cells accumulate in the host during the aging process and are associated with age-related pathogeneses, including cancer. Although persistent…”
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    Journal Article
  6. 6

    Merkel Cell Polyomavirus Small Tumor Antigen Activates Matrix Metallopeptidase-9 Gene Expression for Cell Migration and Invasion by Nwogu, Nnenna, Ortiz, Luz E, Whitehouse, Adrian, Kwun, Hyun Jin

    Published in Journal of virology (15-09-2020)
    “…Merkel cell polyomavirus (MCV) small T antigen (sT) is the main oncoprotein for the development of Merkel cell carcinoma (MCC). MCC is a rare, clinically…”
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  7. 7

    Surface charge of Merkel cell polyomavirus small T antigen determines cell transformation through allosteric FBW7 WD40 domain targeting by Nwogu, Nnenna, Ortiz, Luz E., Kwun, Hyun Jin

    Published in Oncogenesis (New York, NY) (19-05-2020)
    “…Merkel cell polyomavirus (MCV) small T (sT) is the main oncoprotein in Merkel cell carcinoma (MCC) development. A unique domain of sT, LT stabilization domain…”
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    Journal Article
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