Search Results - "Orth, A. P."

Strategy for Probing the Function of Noncoding RNAs Finds a Repressor of NFAT by Willingham, A. T, Orth, A. P, Batalov, S, Peters, E. C, Wen, B. G, Aza-Blanc, P, Hogenesch, J. B, Schultz, P. G

“…Noncoding RNA molecules (ncRNAs) have been implicated in numerous biological processes including transcriptional regulation and the modulation of protein…”
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Sequence, structure and expression of the hemolymph juvenile hormone binding protein gene in the tobacco hornworm, Manduca sexta by Orth, A.P., Doll, S.C., Goodman, W.G.

“…The hemolymph juvenile hormone binding protein (hJHBP) gene of Manduca sexta is a key target of its specific ligand, juvenile hormone (JH). While the cDNA for…”
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The lethal effects of Cyperus iria on Aedes aegypti by Schwartz, A M, Paskewitz, S M, Orth, A P, Tesch, M J, Toong, Y C, Goodman, W G

“…The sedge Cyperus iria, a common weed in rice, contains large amounts of the insect hormone (10R) juvenile hormone III (JH III). Given its widespread…”
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Ligand regulation of juvenile hormone binding protein mRNA in mutant Manduca sexta by Orth, Anthony P., Lan, Que, Goodman, Walter G.

“…Insect hemolymph juvenile hormone binding protein (hJHBP) regulates peripheral titers of its ligands, the juvenile hormones. In larvae of the black ( bl)…”
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Global Analysis of Host-Pathogen Interactions that Regulate Early-Stage HIV-1 Replication by König, Renate, Zhou, Yingyao, Elleder, Daniel, Diamond, Tracy L., Bonamy, Ghislain M.C., Irelan, Jeffrey T., Chiang, Chih-yuan, Tu, Buu P., De Jesus, Paul D., Lilley, Caroline E., Seidel, Shannon, Opaluch, Amanda M., Caldwell, Jeremy S., Weitzman, Matthew D., Kuhen, Kelli L., Bandyopadhyay, Sourav, Ideker, Trey, Orth, Anthony P., Miraglia, Loren J., Bushman, Frederic D., Young, John A., Chanda, Sumit K.

“…Human Immunodeficiency Viruses (HIV-1 and HIV-2) rely upon host-encoded proteins to facilitate their replication. Here, we combined genome-wide siRNA analyses…”
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Recent advances in radioimmunoassay technology for the juvenile hormones by Goodman, W G, Orth, A P, Toong, Y C, Ebersohl, R, Hiruma, K, Granger, N A

“…Recent refinements in juvenile hormone radioimmunoassay technology now make this method significantly more sensitive and easier to use. Rabbit polyclonal…”
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Large-Scale Analysis of the Human and Mouse Transcriptomes by Su, Andrew I., Cooke, Michael P., Ching, Keith A., Hakak, Yaron, Walker, John R., Wiltshire, Tim, Orth, Anthony P., Vega, Raquel G., Sapinoso, Lisa M., Moqrich, Aziz, Patapoutian, Ardem, Hampton, Garret M., Schultz, Peter G., Hogenesch, John B.

“…High-throughput gene expression profiling has become an important tool for investigating transcriptional activity in a variety of biological samples. To date,…”
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Identification of a Family of cAMP Response Element-Binding Protein Coactivators by Genome-Scale Functional Analysis in Mammalian Cells by Iourgenko, Vadim, Zhang, Wenjun, Mickanin, Craig, Daly, Ira, Jiang, Can, Hexham, Jonathan M., Orth, Anthony P., Miraglia, Loren, Meltzer, Jodi, Garza, Dan, Chirn, Gung-Wei, McWhinnie, Elizabeth, Cohen, Dalia, Skelton, Joanne, Terry, Robert, Yu, Yang, Bodian, Dale, Buxton, Frank P., Zhu, Jian, Song, Chuanzheng, Labow, Mark A.

“…This report describes an unbiased method for systematically determining gene function in mammalian cells. A total of 20,704 predicted human full-length cDNAs…”
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A functional genomics approach to the mode of action of apratoxin A by Izpisúa Belmonte, Juan Carlos, Luesch, Hendrik, Orth, Anthony P, DeJesus, Paul D, Raya, R Marina, Walker, John R, Schultz, Peter G, Chanda, Sumit K

“…The cyanobacterial metabolite apratoxin A (1) demonstrates potent cytotoxicity against tumor cell lines by a hitherto unknown mechanism. We have used…”
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Stem Cells by He, H., Emmett, M. R., Marshall, A. G., Ji, Y., Conrad, C. A., Priebe, W., Colman, H., Lang, F. F., Madden, T. L., Kristoffersen, K., Stockhausen, M.-T., Poulsen, H. S., Binder, Z. A., Orr, B., Lim, M., Weingart, J. D., Brem, H., Olivi, A., Riggins, G. J., Gallia, G. L., Litofsky, N. S., Miller, D. C., Rath, P., Anthony, D. C., Feng, Q., Franklin, C., Pei, L., Free, A., Kirk, M. D., Shi, H., Timmer, M., Theiss, H., Juerchott, K., Ries, C., Paron, I., Franz, W., Selbig, J., Guo, K., Tonn, J. C., Schichor, C., Zhou, Y.-H., Hu, Y., Pioli, P. D., Rajneesh, K., Limoli, C. L., Yu, L., Hess, K. R., Linskey, M. E., Faber, F., Jaeger, D., Thorsteinsdottir, J., Albrecht, V., Tonn, J.-C., Price, R., Song, J., Zimmerman, P., Duale, H., Rivera, A., Kaur, B., Parada, L., Cook, C., Chiocca, E. A., Kwon, C.-H., Munoz, D. M., Guha, A., Estrada-Bernal, A., Van Brocklyn, J. R., Gu, C., Mahasenan, K. V., Joshi, K., Gupta, S., Mattson, A., Li, C., Nakano, I., Chi, A. S., Rheinbay, E., Wakimoto, H., Gillespie, S., Kasif, S., Rabkin, S. D., Martuza, R. L., Bernstein, B. E., Skirboll, S. L., Wurdak, H., Zhu, S., Romero, A., Lorger, M., Watson, J., Chiang, C.-y., Zhang, J., Natu, V. S., Lairson, L. L., Walker, J. R., Trussell, C. M., Harsh, G. R., Vogel, H., Felding-Habermann, B., Orth, A. P., Miraglia, L. J., Rines, D. R.

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Identification of the Wnt Signaling Activator Leucine-Rich Repeat in Flightless Interaction Protein 2 by a Genome-Wide Functional Analysis by Liu, Jun, Bang, Anne G., Kintner, Chris, Orth, Anthony P., Chanda, Sumit K., Ding, Sheng, Schultz, Peter G.

“…The Wnt signaling pathway acts ubiquitously in metazoans to control various aspects of embryonic development. Wnt ligands bind their receptors Frizzled and…”
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Genome-Scale Functional Profiling of the Mammalian AP-1 Signaling Pathway by Chanda, Sumit K., White, Suhaila, Orth, Anthony P., Reisdorph, Richard, Miraglia, Loren, Thomas, Russell S., DeJesus, Paul, Mason, Daniel E., Huang, Qihong, Vega, Raquel, Yu, De-Hua, Nelson, Christian G., Smith, Brendan M., Terry, Robert, Linford, Alicia S., Yu, Yang, Chirn, Gung-wei, Song, Chuanzheng, Labow, Mark A., Cohen, Dalia, King, Frederick J., Peters, Eric C., Schultz, Peter G., Vogt, Peter K., Hogenesch, John B., Caldwell, Jeremy S.

“…Large-scale functional genomics approaches are fundamental to the characterization of mammalian transcriptomes annotated by genome sequencing projects…”
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Avulsion Fracture of the Calcaneal Tuberosity: A soft tissue complication from delayed treatment by Radzilani MBChB, M., D’Alton MBChB,(Pret), MMed (Orth), E., Golele, MBChB (Natal), R.G., GP (SA), MMed (Orth), FCS Orth (SA), MF

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The promise of genomics to identify novel therapeutic targets by Orth, Anthony P, Batalov, Serge, Perrone, Mark, Chanda, Sumit K

“…The cataloguing of the human genome has provided an unprecedented prospectus for target identification and drug discovery. A current analysis indicates that…”
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Identification of novel mammalian growth regulatory factors by genome-scale quantitative image analysis by Harada, Josephine N, Bower, Kristen E, Orth, Anthony P, Callaway, Scott, Nelson, Christian G, Laris, Casey, Hogenesch, John B, Vogt, Peter K, Chanda, Sumit K

“…Functional profiling technologies using arrayed collections of genome-scale siRNA and cDNA arrayed libraries enable the comprehensive global analysis of gene…”
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Effects of stress on the hemolymph juvenile hormone binding protein titers of Manduca sexta by Tauchman, Seth J., Lorch, Jeffrey M., Orth, Anthony P., Goodman, Walter G.

“…External stressors disrupt physiological homeostasis; in insects, the response to stress may result in delayed development as the animal attempts to restore…”
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Embryonic expression of juvenile hormone binding protein and its relationship to the toxic effects of juvenile hormone in Manduca sexta by Orth, Anthony P, Tauchman, Seth J, Doll, Sharon C, Goodman, Walter G

“…The juvenile hormones (JHs) regulate a diverse array of insect developmental and reproductive processes. One molecular target of JH action is its transporter,…”
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Allelic variation in the hemolymph juvenile hormone binding protein gene of Manduca sexta by Young, Joshua K., Orth, Anthony P., Goodman, Walter G.

“…Peripheral distribution of the insect juvenile hormones (JHs) requires hemolymph transport proteins. A comparison of three strains of the tobacco hornworm…”
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Socialism—The American Pattern by Orth, Andrew P.

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