Search Results - "Ortega‐Sanz, Laura"
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Lived experiences of mental health nurses who care for clients who are parents: An approximation of Tronto's definition of care
Published in Journal of psychiatric and mental health nursing (01-10-2024)“…Accessible Summary What is known on the subject Adult psychiatric services typically focus on the mental health needs of the client but they do not support his…”
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Nurses’ emotions on care relationship: A qualitative study
Published in Journal of nursing management (01-11-2020)“…Aims To describe nurses’ experiences regarding the care relationship built with medical–surgical patients in acute hospitalization units and the association…”
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Improved Leukemia Clearance After Adoptive Transfer of NK Cells Expressing the Bone Marrow Homing Receptor CXCR4R334X
Published in HemaSphere (01-11-2023)Get full text
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Magnetic Nanoparticles Attached to the NK Cell Surface for Tumor Targeting in Adoptive Transfer Therapies Does Not Affect Cellular Effector Functions
Published in Frontiers in immunology (30-08-2019)“…Adoptive cell transfer therapy is currently one of the most promising approaches for cancer treatment. This therapy has some limitations, however, such as the…”
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422 Hijacking upregulated E-selectin while boosting SDF-1α sensing rewires infused NK cells to the AML-perturbed bone marrow
Published in Journal for immunotherapy of cancer (01-11-2023)“…BackgroundInfusion of natural killer (NK) cells can induce anti-tumor responses in patients. Currently, most efforts to further improve the efficacy focuses on…”
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T cells loaded with magnetic nanoparticles are retained in peripheral lymph nodes by the application of a magnetic field
Published in Journal of nanobiotechnology (22-01-2019)“…T lymphocytes are highly dynamic elements of the immune system with a tightly regulated migration. T cell-based transfer therapies are promising therapeutic…”
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Magnetic targeting of adoptively transferred tumour-specific nanoparticle-loaded CD8 + T cells does not improve their tumour infiltration in a mouse model of cancer but promotes the retention of these cells in tumour-draining lymph nodes
Published in Journal of nanobiotechnology (06-08-2019)“…Adoptive T cell-transfer (ATC) therapy is a highly promising cancer-treatment approach. However, in vivo-administered T cells tend to disperse, with only a…”
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Reflective based learning for nursing ethical competency during clinical practices
Published in Nursing ethics (01-06-2023)“…Background A combination of theoretical and practical approaches is required to learn and acquire ethical competencies in caring. Occasionally, reflection on…”
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Improving Tumor Retention of Effector Cells in Adoptive Cell Transfer Therapies by Magnetic Targeting
Published in Pharmaceutics (27-08-2020)“…Adoptive cell transfer therapy is a promising anti-tumor immunotherapy in which effector immune cells are transferred to patients to treat tumors. However, one…”
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Redirecting NK cells to the lymph nodes to augment their lymphoma-targeting capacity
Published in NPJ precision oncology (20-05-2024)“…CAR-NK cells can induce remission in lymphoma patients. We speculate that the full potential of adoptive NK cell immunotherapy against lymphoma is restricted…”
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PI3K p85 β regulatory subunit deficiency does not affect NK cell differentiation and increases NKG2D‐mediated activation
Published in Journal of leukocyte biology (01-12-2016)“…Deficiency of the p85β regulatory subunit of PI3K does not affect NK cell differentiation and increases NK cell activity. Activation of NK cells depends on a…”
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Harnessing upregulated E-selectin while enhancing SDF-1α sensing redirects infused NK cells to the AML-perturbed bone marrow
Published in Leukemia (01-03-2024)“…Increased bone marrow (BM) homing of NK cells is associated with positive outcome in patients with acute myeloid leukemia (AML) treated within adoptive NK cell…”
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Polyethylenimine-coated superparamagnetic iron oxide nanoparticles impair in vitro and in vivo angiogenesis
Published in Nanomedicine (01-10-2019)“…Endothelial cells are essential to tumor vascularization and impairing their activity can potentially limit tumor growth. Since polyethylenimine (PEI)-coated…”
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Superparamagnetic iron oxide nanoparticle uptake alters M2 macrophage phenotype, iron metabolism, migration and invasion
Published in Nanomedicine (01-05-2016)“…Abstract Superparamagnetic iron oxide nanoparticles (SPIONs) have shown promise as contrast agents and nanocarriers for drug delivery. Their impact on…”
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Iron Oxide Nanoparticle Coatings Dictate Cell Outcomes Despite the Influence of Protein Coronas
Published in ACS applied materials & interfaces (24-02-2021)“…A critical issue in nanomedicine is to understand the complex dynamics that dictate the interactions of nanoparticles (NPs) with their biological milieu. The…”
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Time-course assessment of the aggregation and metabolization of magnetic nanoparticles
Published in Acta biomaterialia (01-08-2017)“…[Display omitted] To successfully develop biomedical applications for magnetic nanoparticles, it is imperative that these nanoreagents maintain their magnetic…”
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KIR2DS1 and KIR2DL1-C245 Dominantly Repress NK Cell Degranulation Triggered by Monoclonal or Bispecific Antibodies, whereas Education by Uptuning Inhibitory Killer Ig-related Receptors Exerts No Advantage in Ab-dependent Cellular Cytotoxicity
Published in The Journal of immunology (1950) (01-03-2024)“…NK cell responsiveness to target cells is tuned by interactions between inhibitory NK cell receptors and their cognate HLA class I ligands in a process termed…”
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Contraceptive counselling experiences in Spain in the process of creating a web-based contraceptive decision support tool: a qualitative study
Published in Reproductive health (27-11-2021)“…The choice of contraceptive method is a complex decision, and professionals should offer counselling based on the preferences, values and personal situation of…”
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Contraceptive counselling experiences in Spain in the process of creating a web-based contraceptive decision support tool: a qualitative study
Published in Reproductive health (01-11-2021)“…Resumen sencillo en Español En España, la población puede utilizar una gran variedad de métodos anticonceptivos. Los profesionales, implicados en el…”
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