Search Results - "Ortega, Jose A."

GSK-3β, FYN, and DYRK1A: Master Regulators in Neurodegenerative Pathways by Demuro, Stefania, Di Martino, Rita M. C., Ortega, Jose A., Cavalli, Andrea

“…Protein kinases (PKs) have been recognized as central nervous system (CNS)-disease-relevant targets due to their master regulatory role in different signal…”
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Electroforming of Implantable Tubular Magnetic Microrobots for Wireless Ophthalmologic Applications by Chatzipirpiridis, George, Ergeneman, Olgaç, Pokki, Juho, Ullrich, Franziska, Fusco, Stefano, Ortega, José A., Sivaraman, Kartik M., Nelson, Bradley J., Pané, Salvador

“…Magnetic tubular implantable micro­robots are batch fabricated by electroforming. These microdevices can be used in targeted drug delivery and minimally…”
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Factors in the Pathophysiology of the Liver Ischemia-Reperfusion Injury by Montalvo-Jave, Eduardo E., M.D, Escalante-Tattersfield, Tomas, M.D, Ortega-Salgado, Jose A., M.D, Piña, Enrique, M.D., Ph.D, Geller, David A., M.D

“…Hepatic ischemia-reperfusion injury is commonplace in liver surgery, particularly in hepatic transplantation, hepatic resection, and trauma. The signaling…”
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Efficiency and lead uptake mechanism of a phosphonate functionalized mesoporous silica through P/Pb association ratio by Gutiérrez-Ortega, José A., Gómez-Salazar, Sergio, Shenderovich, Ilya G., Manríquez-González, Ricardo

“…Chemically stable phosphonate functionalized mesoporous silica material SGMP6 has been obtained by means of conventional sol-gel methodology. This material…”
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Structure-based design of CDC42 effector interaction inhibitors for the treatment of cancer by Jahid, Sohail, Ortega, Jose A., Vuong, Linh M., Acquistapace, Isabella Maria, Hachey, Stephanie J., Flesher, Jessica L., La Serra, Maria Antonietta, Brindani, Nicoletta, La Sala, Giuseppina, Manigrasso, Jacopo, Arencibia, Jose M., Bertozzi, Sine Mandrup, Summa, Maria, Bertorelli, Rosalia, Armirotti, Andrea, Jin, Rongsheng, Liu, Zheng, Chen, Chi-Fen, Edwards, Robert, Hughes, Christopher C.W., De Vivo, Marco, Ganesan, Anand K.

“…CDC42 family GTPases (RHOJ, RHOQ, CDC42) are upregulated but rarely mutated in cancer and control both the ability of tumor cells to invade surrounding tissues…”
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Multiscale structural and lithologic controls in the development of stream potholes on granite bedrock rivers by Ortega, Jose A., Gómez-Heras, Miguel, Perez-López, Raúl, Wohl, Ellen

“…Jointing, veins, dikes, and fracture patterns influence the genesis of potholes in bedrock rivers. We use measures of surface rock strength (Schmidt hammer…”
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Insights into deglaciation of the largest ice-free area in the South Shetland Islands (Antarctica) from quantitative analysis of the drainage system by Mink, Sandra, López-Martínez, Jerónimo, Maestro, Adolfo, Garrote, Julio, Ortega, José A., Serrano, Enrique, Durán, Juan José, Schmid, Thomas

“…A quantitative geomorphic analysis of the drainage system on Byers Peninsula, Livingston Island, has been carried out in order to study the relief evolution,…”
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Animal use of fence crossings in southwestern rangelands by Zoromski, Lisa D., DeYoung, Randy W., Goolsby, John A., Foley, Aaron M., Ortega‐Santos, Jose A., Hewitt, David G., Campbell, Tyler A.

“…Net‐wire fencing built to confine livestock is common on rangelands in the Southwestern USA, yet the impacts of livestock fencing on wildlife are largely…”
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Waterfalls on the eastern side of Rocky Mountain National Park, Colorado, USA by Ortega, Jose A., Wohl, Ellen, Livers, Bridget

“…We examined 30 waterfalls on the eastern side of Rocky Mountain National Park in Colorado, USA, to evaluate whether drainage area or bedrock properties as…”
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Interpolation of GPS and Geological Data Using InSAR Deformation Maps: Method and Application to Land Subsidence in the Alto Guadalentín Aquifer (SE Spain) by Bejar-Pizarro, Marta, Guardiola-Albert, Carolina, Garcia-Cardenas, Ramon P, Herrera, Gerardo, Barra, Anna, Molina, Antonio Lopez, Tessitore, Serena, Staller, Alejandra, Ortega-Becerril, Jose A, Garcia-Garcia, Ramon P

“…Land subsidence resulting from groundwater extractions is a global phenomenon adversely affecting many regions worldwide. Understanding the governing processes…”
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Interaction between the 5-HT system and the basal ganglia: functional implication and therapeutic perspective in Parkinson's disease by Miguelez, Cristina, Morera-Herreras, Teresa, Torrecilla, Maria, Ruiz-Ortega, Jose A, Ugedo, Luisa

“…The neurotransmitter serotonin (5-HT) has a multifaceted function in the modulation of information processing through the activation of multiple receptor…”
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Revised nomenclature for allergy for global use: Report of the Nomenclature Review Committee of the World Allergy Organization, October 2003 by Johansson, S.G.O, Bieber, Thomas, Dahl, Ronald, Friedmann, Peter S, Lanier, Bobby Q, Lockey, Richard F, Motala, Cassim, Ortega Martell, Jose A, Platts-Mills, Thomas A.E, Ring, Johannes, Thien, Frank, Van Cauwenberge, Paul, Williams, Hywel C

“…The nomenclature proposed in the October 2003 report of the Nomenclature Review Committee of the World Allergy Organization is an update of the European…”
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Sediment Response after Wildfires in Mountain Streams and Their Effects on Cultural Heritage: The Case of the 2021 Navalacruz Wildfire (Avila, Spain) by Ortega-Becerril, Jose A., Suarez, Clara, Vázquez-Tarrío, Daniel, Garrote, Julio, Gomez-Heras, Miguel

“…The 2021 Navalacruz wildfire occurred in a mountainous area in the Sistema Central (Spain). Despite having an average low severity index (dNBR), the loss of…”
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Microrobotics: Electroforming of Implantable Tubular Magnetic Microrobots for Wireless Ophthalmologic Applications (Adv. Healthcare Mater. 2/2015) by Chatzipirpiridis, George, Ergeneman, Olgaç, Pokki, Juho, Ullrich, Franziska, Fusco, Stefano, Ortega, José A., Sivaraman, Kartik M., Nelson, Bradley J., Pané, Salvador

“…The fabrication of implantable magnetic tubular microrobots for use in targeted drug delivery and minimally invasive surgery for ophthalmologic applications is…”
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CRISPR/Cas9 mutagenesis in Volvox carteri by Ortega‐Escalante, José A., Jasper, Robyn, Miller, Stephen M.

“…Summary Volvox carteri and other volvocine green algae comprise an excellent model for investigating developmental complexity and its origins. Here we describe…”
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Surface Mechanical Effects of Wildfires on Rocks in Climbing Areas by Yeste-Lizán, Pablo, Gomez-Heras, Miguel, García-Rodríguez, Manuel, Pérez-López, Raúl, Carcavilla, Luis, Ortega-Becerril, Jose A.

“…Wildfires are widely recognized as a cause of mechanical damage to rocks. Nevertheless, previous research has neglected how wildfires might impact sport…”
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As(V) removal from aqueous media using an environmentally friendly zwitterion L-cysteine functionalized silica adsorbent by Moran-Salazar, Rene G., Carbajal-Arizaga, Gregorio G., Gutierréz-Ortega, José A., Badillo-Camacho, Jessica, Manríquez-González, Ricardo, Shenderovich, Ilya G., Gómez-Salazar, Sergio

“…[Display omitted] •Novel L-cysteine hybrid adsorbent prepared by sol–gel route used in As(V) removal.•High As(V) uptakes by adsorbent and fast adsorption…”
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Galantamine-memantine hybrids for Alzheimer's disease: The influence of linker rigidity in biological activity and pharmacokinetic properties by Basagni, Filippo, Ortega, Jose A., Bertozzi, Sine M., Armirotti, Andrea, Summa, Maria, Bertorelli, Rosalia, Bartolini, Manuela, Mellor, Ian R., Bedeschi, Martina, Bottegoni, Giovanni, Lembo, Vittorio, Minarini, Anna, Cavalli, Andrea, Rosini, Michela

“…Neurodegenerative processes characterizing Alzheimer's disease (AD) are strictly related to the impairment of cholinergic and glutamatergic neurotransmitter…”
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Morphometric measurements of bedrock rivers at different spatial scales and applications to geomorphological heritage research by Gomez-Heras, Miguel, Ortega-Becerril, Jose A., Garrote, Julio, Fort, Rafael, Lopez-Gonzalez, Laura

“…Morphometric characterisation is particularly relevant in the study of geomorphological heritage. 3D modelling techniques have been proven as very useful tools…”
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ARN25068, a versatile starting point towards triple GSK-3β/FYN/DYRK1A inhibitors to tackle tau-related neurological disorders by Demuro, Stefania, Sauvey, Conall, Tripathi, Shailesh K., Di Martino, Rita M.C., Shi, Da, Ortega, Jose A., Russo, Debora, Balboni, Beatrice, Giabbai, Barbara, Storici, Paola, Girotto, Stefania, Abagyan, Ruben, Cavalli, Andrea

“…The human kinome plays a crucial role in several pathways. Its dysregulation has been linked to diverse central nervous system (CNS)-related disorders with a…”
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