Search Results - "Ortega, Hugo H"

Developmental programming: prenatal androgen excess disrupts ovarian steroid receptor balance by Ortega, Hugo H, Salvetti, Natalia R, Padmanabhan, Vasantha

“…Steroid hormones play an important role in reproduction and the receptors through which they signal change in a developmental time, follicle stage, and…”
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Non-clinical safety assessment and in vivo biodistribution of CoviFab, an RBD-specific F(ab′)2 fragment derived from equine polyclonal antibodies by Salinas, Facundo, Marelli, Belkis E., Sanguineti, Santiago, Goldbaum, Fernando, Muñoz, Luciana, Etchevers, Lucas, Silvestrini, Paula, Notaro, Ulises S., Salvetti, Natalia R., Zylberman, Vanesa, Ortega, Hugo H.

“…The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has required the urgent development of new therapies, among which passive immunotherapy is…”
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Molecular aspects of bovine cystic ovarian disease pathogenesis by Ortega, Hugo H, Marelli, Belkis E, Rey, Florencia, Amweg, Ayelen N, Díaz, Pablo U, Stangaferro, Matías L, Salvetti, Natalia R

“…Cystic ovarian disease (COD) is one of the main causes of reproductive failure in cattle and causes severe economic loss to the dairy farm industry because it…”
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Biocompatible Hydrogel for Intra-Articular Implantation Comprising Cationic and Anionic Polymers of Natural Origin: In Vivo Evaluation in a Rabbit Model by Bierbrauer, Karina L, Alasino, Roxana V, Barclay, Fernando E, Belotti, Eduardo M, Ortega, Hugo H, Beltramo, Dante M

“…We describe the functional capability of a cross-linked hydrogel composed of sulfated glycosaminoglycans and a cationic cellulose by conducting trials on…”
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Alpha-mannosidosis caused by toxic plants in ruminants of Argentina by CHOLICH, LUCIANA A., MARTINEZ, AGUSTÍN, MICHELOUD, JUAN F., PISTÁN, MARÍA E., GARCÍA, ENRIQUE N., ROBLES, CARLOS A., ORTEGA, HUGO H., GIMENO, EDUARDO J.

“…Abstract It is well known that several of the swainsonine-containing plant species found widespread around the world have a negative economic impact in each…”
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Follicular Cysts: A Single Sign and Different Diseases. A View from Comparative Medicine by Ortega, Hugo H, Díaz, Pablo U, Salvetti, Natalia R, Hein, Gustavo J, Marelli, Belkis E, Rodríguez, Fernanda M, Stassi, Antonela F, Rey, Florencia

“…Ovarian cystic follicles are the sign of important causes of reproductive failure in numerous species. In this review, some morphological, endocrinological and…”
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mRNA expression pattern of gonadotropin receptors in bovine follicular cysts by Marelli, Belkis E, Diaz, Pablo U, Salvetti, Natalia R, Rey, Florencia, Ortega, Hugo H

“…Abstract Follicular growth and steroidogenesis are dependent on gonadotropin binding to their receptors in granulosa and theca cells of ovarian follicles. The…”
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Cross-protection and cross-neutralization capacity of ancestral and VOC-matched SARS-CoV-2 adenoviral vector-based vaccines by Vinzón, Sabrina E., Lopez, María V., Cafferata, Eduardo G. A., Soto, Ariadna S., Berguer, Paula M., Vazquez, Luciana, Nusblat, Leonora, Pontoriero, Andrea V., Belotti, Eduardo M., Salvetti, Natalia R., Viale, Diego L., Vilardo, Ariel E., Avaro, Martin M., Benedetti, Estefanía, Russo, Mara L., Dattero, María E., Carobene, Mauricio, Sánchez-Lamas, Maximiliano, Afonso, Jimena, Heitrich, Mauro, Cristófalo, Alejandro E., Otero, Lisandro H., Baumeister, Elsa G., Ortega, Hugo H., Edelstein, Alexis, Podhajcer, Osvaldo L.

“…COVID-19 vaccines were originally designed based on the ancestral Spike protein, but immune escape of emergent Variants of Concern (VOC) jeopardized their…”
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Microscopic Characterization of Follicular Structures in Letrozole-induced Polycystic Ovarian Syndrome in the Rat by Baravalle, Celina, Salvetti, Natalia R., Mira, Gustavo A., Pezzone, Natalia, Ortega, Hugo H.

“…Our objective was to characterize the tissular distribution of relevant cytoskeletal proteins, cellular adhesion molecules and proliferation markers and…”
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Comparison of complement system activity amongst wild and domestic animals by Moleón, María S, Merchant, Mark E, Ortega, Hugo H, Siroski, Pablo A

“…[...]unsensitized sheep red blood cell hemolysis can be successfully used for the evaluation of innate immune system activities in non-mammalian species;…”
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A Single Dose of a Hybrid hAdV5-Based Anti-COVID-19 Vaccine Induces a Long-Lasting Immune Response and Broad Coverage against VOC by López, M Verónica, Vinzón, Sabrina E, Cafferata, Eduardo G A, Núñez, Felipe J, Soto, Ariadna, Sanchez-Lamas, Maximiliano, Afonso, M Jimena, Aguilar-Cortes, Diana, Ríos, Gregorio D, Maricato, Juliana T, Braconi, Carla T, Silveira, Vanessa B, Andrad, Tatiane M, Bonetti, Tatiana C S, Ramos Janini, Luiz M, Girão, Manoel J B C, Llera, Andrea S, Gomez, Karina A, Ortega, Hugo H, Berguer, Paula M, Podhajcer, Osvaldo L

“…Most approved vaccines against COVID-19 have to be administered in a prime/boost regimen. We engineered a novel vaccine based on a chimeric human adenovirus 5…”
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An imbalance between apoptosis and proliferation contributes to follicular persistence in polycystic ovaries in rats by Salvetti, Natalia R, Panzani, Carolina G, Gimeno, Eduardo J, Neme, Leandro G, Alfaro, Natalia S, Ortega, Hugo H

“…Cystic ovarian disease is an important cause of infertility that affects bovine, ovine, caprine and porcine species and even human beings. Alterations in the…”
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Parametrial Adipose Tissue and Metabolic Dysfunctions Induced by Fructose-rich Diet in Normal and Neonatal-androgenized Adult Female Rats by Alzamendi, Ana, Castrogiovanni, Daniel, Ortega, Hugo H, Gaillard, Rolf C, Giovambattista, Andres, Spinedi, Eduardo

“…Hyperandrogenemia predisposes an organism toward developing impaired insulin sensitivity. The aim of our study was to evaluate endocrine and metabolic effects…”
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Sympathetic nerve activity in normal and cystic follicles from isolated bovine ovary: local effect of beta-adrenergic stimulation on steroid secretion by Paredes, Alfonso H, Salvetti, Natalia R, Diaz, Ariel E, Dallard, Bibiana E, Ortega, Hugo H, Lara, Hernan E

“…Cystic ovarian disease (COD) is an important cause of abnormal estrous behavior and infertility in dairy cows. COD is mainly observed in high-yielding dairy…”
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Developmental Programming: Effect of Prenatal Steroid Excess on Intraovarian Components of Insulin Signaling Pathway and Related Proteins in Sheep1 by Ortega, Hugo H, Rey, Florencia, Velazquez, Melisa M.L, Padmanabhan, Vasantha

“…Prenatal testosterone (T) excess increases ovarian follicular recruitment, follicular persistence, insulin resistance, and compensatory hyperinsulinemia…”
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Effect of Parenteral Supplementation of Minerals and Vitamins on Oxidative Stress Biomarkers and Hepatic Fatty Acid Metabolism in Dairy Cows During the Transition Period by Barcarolo, Daiana, Angeli, Emmanuel, Etchevers, Lucas, Ribas, Lucas E., Matiller, Valentina, Rey, Florencia, Ortega, Hugo H., Hein, Gustavo J.

“…In the present work we aimed to study the effects of parenteral vitamin and mineral supplementation on hepatic fatty acid metabolism as well as on the…”
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Developmental Programming: Prenatal Steroid Excess Disrupts Key Members of Intraovarian Steroidogenic Pathway in Sheep by Padmanabhan, Vasantha, Salvetti, Natalia R, Matiller, Valentina, Ortega, Hugo H

“…Prenatal testosterone (T) excess disrupts ovarian cyclicity and increases circulating estradiol levels as well as follicular recruitment and persistence…”
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Anti-echinococcal effect of metformin in advanced experimental cystic echinococcosis: reprogrammed intermediary carbon metabolism in the parasite by Loos, Julia A, Negro, Perla S, Ortega, Hugo H, Salinas, Facundo J, Arán, Martín, Pellizza, Leonardo, Salerno, Graciela L, Cumino, Andrea C

“…Metformin, a safe biguanide derivative with antiproliferative properties, has shown antiparasitic efficacy against the larval stage. Hence, we assessed the…”
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New inhibitor targeting Acyl-CoA synthetase 4 reduces breast and prostate tumor growth, therapeutic resistance and steroidogenesis by Castillo, Ana F., Orlando, Ulises D., Maloberti, Paula M., Prada, Jesica G., Dattilo, Melina A., Solano, Angela R., Bigi, María M., Ríos Medrano, Mayra A., Torres, María T., Indo, Sebastián, Caroca, Graciela, Contreras, Hector R., Marelli, Belkis E., Salinas, Facundo J., Salvetti, Natalia R., Ortega, Hugo H., Lorenzano Menna, Pablo, Szajnman, Sergio, Gomez, Daniel E., Rodríguez, Juan B., Podesta, Ernesto J.

“…Acyl-CoA synthetase 4 (ACSL4) is an isoenzyme of the fatty acid ligase-coenzyme-A family taking part in arachidonic acid metabolism and steroidogenesis. ACSL4…”
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PEGylation of Chrysin Improves Its Water Solubility while Preserving the In Vitro Biological Activity by Oggero, Julia, Gasser, Fátima B., Zacarías, Silvia M., Burns, Patricia, Baravalle, María E., Renna, Maria Sol, Ortega, Hugo H., Vaillard, Santiago E., Vaillard, Victoria A.

“…Chrysin is a natural flavonoid that despite having numerous biological properties, its therapeutic value is limited due to its very low solubility in aqueous…”
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