Search Results - "Orrenius, C"

Formation and reduction of glutathione-protein mixed disulfides during oxidative stress. A study with isolated hepatocytes and menadione (2-methyl-1,4-naphthoquinone) by Bellomo, G, Mirabelli, F, DiMonte, D, Richelmi, P, Thor, H, Orrenius, C, Orrenius, S

“…Incubation of isolated rat hepatocytes with menadione (2-methyl-1,4-naphthoquinone) resulted in a dose-dependent depletion of intracellular reduced glutathione…”
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Simple conformation space search protocols for the evaluation of enantioselectivity of lipases by Orrenius, C, van Heusden, C, van Ruiten, J, Overbeeke, P L, Kierkels, H, Duine, J A, Jongejan, J A

“…Two computational protocols have been evaluated regarding their ability to reproduce the enthalpic part of lipase enantioselectivity by forcefield potential…”
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Second-harmonic generation in a novel crosslinked pyroelectric liquid crystal polymer (PLCP) by HERMANN, D. S., RUDQUIST, P., LAGERWALL, S. T., KOMITOV, L., STEBLER, B., LINDGREN, M., TROLLSAS, M., SAHLEN, F., HULT, A., GEDDE, U. W., ORRENIUS, C., NORIN, T.

“…We report second-harmonic generation in samples with a pyroelectric liquid crystal polymer (PLCP) prepared from the ferroelectric liquid crystalline acrylate…”
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Influence of Molecular Flexibility and Polar Surface Area Metrics on Oral Bioavailability in the Rat by Lu, Jing J, Crimin, Kimberly, Goodwin, Jay T, Crivori, Patrizia, Orrenius, Christian, Xing, Li, Tandler, Peter J, Vidmar, Thomas J, Amore, Benny M, Wilson, Alan G. E, Stouten, Pieter F. W, Burton, Philip S

“…The relationship of rotatable bond count (N rot) and polar surface area (PSA) with oral bioavailability in rats was examined for 434 Pharmacia compounds and…”
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Enantioselective preparation of the stereoisomers of 4-methylheptan-3-ol using Candida antarctica lipase B by Unelius, C. Rikard, Sandell, J., Orrenius, C.

“…The four stereoisomers of 4-methylheptan-3-ol were prepared through fractional crystallization of a mixture of their racemic 4-methylhept-3-yl…”
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Linear and Nonlinear Methods in Modeling the Aqueous Solubility of Organic Compounds by Catana, Cornel, Gao, Hua, Orrenius, Christian, Stouten, Pieter F. W

“…Solubility data for 930 diverse compounds have been analyzed using linear Partial Least Square (PLS) and nonlinear PLS methods, Continuum Regression (CR), and…”
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Molecular recognition of sec-alcohol enantiomers by Candida antarctica lipase B by Rotticci, Didier, Hæffner, Fredrik, Orrenius, Christian, Norin, Torbjörn, Hult, Karl

“…A model to explain the enantioselectivity of Candida antarctica lipase B towards sec-alcohols based on structure activity and molecular modelling is presented…”
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Model based on GRID-derived descriptors for estimating CYP3A4 enzyme stability of potential drug candidates by Crivori, Patrizia, Zamora, Ismael, Speed, Bill, Orrenius, Christian, Poggesi, Italo

“…A number of computational approaches are being proposed for an early optimization of ADME (absorption, distribution, metabolism and excretion) properties to…”
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The Candida antarctica lipase B catalysed kinetic resolution of seudenol in non-aqueous media of controlled water activity by Orrenius, Christian, Norin, Torbjörn, Hult, Karl, Carrea, Giacomo

“…For further investigation of the kinetic resolutions in transesterification reactions with the highly enantioselective Candida antarctica lipase B, an easy to…”
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Kinetic resolutions of amine and thiol analogues of secondary alcohols catalyzed by the Candida antarctica lipase B by Öhrner, Niklas, Orrenius, Christian, Mattson, Anders, Norin, Torbjörn, Hult, Karl

“…Chiral amine and thiol analogues of secondary alcohols were tested as substrates for the Candida antarctica lipase B with emphasis on lipase enantioselectivity…”
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Preparation of a Novel Cross-Linked Polymer for Second-Order Nonlinear Optics by Trollsås, Mikael, Orrenius, Christian, Sahlén, Fredrik, Gedde, Ulf W, Norin, Torbjörn, Hult, Anders, Hermann, David, Rudquist, Per, Komitov, Lachezar, Lagerwall, Sven T, Lindström, Jan

“…A novel cross-linked pyroelectric polymer with pronounced second-order nonlinear optical properties has been prepared. A multistep synthesis with several…”
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Model based on GRID-derived descriptors for estimating CYP3A4 enzyme stability of potential drug candidates by Crivori, Patrizia, Zamora, Ismael, Speed, Bill, Orrenius, Christian, Poggesi, Italo

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Enantiomerically enriched bifunctional sec-alcohols prepared by Candida antarctica lipase B catalysis. Evidence of non-steric interactions by Rotticci, Didier, Orrenius, Christian, Hult, Karl, Norin, Torbjörn

“…Transesterification catalysed by Candida antarctica lipase B was used for the preparation of enantiomerically enriched bifunctional sec-alcohols. The…”
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Candida antarctica lipase B catalysed kinetic resolutions: Substrate structure requirements for the preparation of enantiomerically enriched secondary alcanols by Orrenius, Christian, Öhrner, Niklas, Rotticci, Didier, Mattson, Anders, Hult, Karl, Norin, Torbjörn

“…The lipase B of the Candida antarctica yeast displays high enantioselectivity in transesterification reactions with chiral secondary alcohols in non-aqueous…”
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Enthalpic and entropic contributions to lipase enantioselectivity by Overbeeke, P.L.Antoine, Orrenius, S.Christian, Jongejan, Jaap A, Duine, Johannis A

“…The enantioselective properties of lipases in the kinetic resolution of chiral substrates are conveniently expressed as the enantiomeric ratio, E. It has been…”
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