Search Results - "Orozco, Natalia"

Inhibition of the B7-H3 immune checkpoint limits tumor growth by enhancing cytotoxic lymphocyte function by Lee, Young-hee, Martin-Orozco, Natalia, Zheng, Peilin, Li, Jing, Zhang, Peng, Tan, Haidong, Park, Hyun Jung, Jeong, Mira, Chang, Seon Hee, Kim, Byung-Seok, Xiong, Wei, Zang, Wenjuan, Guo, Li, Liu, Yang, Dong, Zhong-jun, Overwijk, Willem W, Hwu, Patrick, Yi, Qing, Kwak, Larry, Yang, Zhiying, Mak, Tak W, Li, Wei, Radvanyi, Laszlo G, Ni, Ling, Liu, Dongfang, Dong, Chen

“…The interaction between tumor and the immune system is still poorly understood. Significant clinical responses have been achieved in cancer patients treated…”
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Th17 cells promote pancreatic inflammation but only induce diabetes efficiently in lymphopenic hosts after conversion into Th1 cells by Martin-Orozco, Natalia, Chung, Yeonseok, Chang, Seon Hee, Wang, Yi-Hong, Dong, Chen

“…IDDM is characterized by leukocyte invasion to the pancreatic tissues followed by immune destruction of the islets. Despite the important function of Th17…”
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The self-association equilibrium of DNAJA2 regulates its interaction with unfolded substrate proteins and with Hsc70 by Velasco-Carneros, Lorea, Cuéllar, Jorge, Dublang, Leire, Santiago, César, Maréchal, Jean-Didier, Martín-Benito, Jaime, Maestro, Moisés, Fernández-Higuero, José Ángel, Orozco, Natalia, Moro, Fernando, Valpuesta, José María, Muga, Arturo

“…J-domain proteins tune the specificity of Hsp70s, engaging them in precise functions. Despite their essential role, the structure and function of many J-domain…”
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Author Correction: The self-association equilibrium of DNAJA2 regulates its interaction with unfolded substrate proteins and with Hsc70 by Velasco-Carneros, Lorea, Cuéllar, Jorge, Dublang, Leire, Santiago, César, Maréchal, Jean-Didier, Martín-Benito, Jaime, Maestro, Moisés, Fernández-Higuero, José Ángel, Orozco, Natalia, Moro, Fernando, Valpuesta, José María, Muga, Arturo

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Prevalence and genotype of Toxoplasma gondii in stranded Hawaiian cetaceans by Landrau-Giovannetti, N, Waltzek, TB, López-Orozco, N, Su, C, Rotstein, D, Levine, G, Rodrigues, TCS, Silva-Krott, I, Humann, C, West, K

“…Toxoplasma gondii is a significant threat to endangered Hawaiian wildlife including birds and marine mammals. To estimate the prevalence of T. gondii in…”
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Truncation-Driven Lateral Association of α-Synuclein Hinders Amyloid Clearance by the Hsp70-Based Disaggregase by Franco, Aitor, Cuéllar, Jorge, Fernández-Higuero, José Ángel, de la Arada, Igor, Orozco, Natalia, Valpuesta, José M, Prado, Adelina, Muga, Arturo

“…The aggregation of α-synuclein is the hallmark of a collective of neurodegenerative disorders known as synucleinopathies. The tendency to aggregate of this…”
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T-cell tolerance or function is determined by combinatorial costimulatory signals by Nurieva, Roza, Thomas, Sunil, Nguyen, Thang, Martin-Orozco, Natalia, Wang, Ying, Kaja, Murali-Krishna, Yu, Xue-Zhong, Dong, Chen

“…Activated in immune responses, T lymphocytes differentiate into effector cells with potent immune function. CD28 is the most prominent costimulatory receptor…”
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An overview of seventy years of research (1944-2014) on toxoplasmosis in Colombia, South America by Cañón-Franco, William Alberto, López-Orozco, Natalia, Gómez-Marín, Jorge Enrique, Dubey, Jitender P

“…This paper summarizes prevalence of Toxoplasma gondii in humans and animals and associated correlates of infection, clinical spectrum of disease in humans, and…”
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Preclinical evaluation of a SARS-CoV-2 mRNA vaccine PTX-COVID19-B by Liu, Jun, Budylowski, Patrick, Samson, Reuben, Griffin, Bryan D, Babuadze, Giorgi, Rathod, Bhavisha, Colwill, Karen, Abioye, Jumai A, Schwartz, Jordan A, Law, Ryan, Yip, Lily, Ahn, Sang Kyun, Chau, Serena, Naghibosadat, Maedeh, Arita, Yuko, Hu, Queenie, Yue, Feng Yun, Banerjee, Arinjay, Hardy, W Rod, Mossman, Karen, Mubareka, Samira, Kozak, Robert A, Pollanen, Michael S, Martin Orozco, Natalia, Gingras, Anne-Claude, Marcusson, Eric G, Ostrowski, Mario A

“…Safe and effective vaccines are needed to end the COVID-19 pandemic. Here, we report the preclinical development of a lipid nanoparticle–formulated SARS-CoV-2…”
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Experimental assessment of the integration of in situ removal of ethanol by pervaporation with a simultaneous saccharification-fermentation process by Orozco-González, Natalia, Bustamante, Felipe, Acosta-Cárdenas, Alejandro

“…ABSTRACT BACKGROUND The effect of process integration in bioethanol productivity was experimentally evaluated by coupling an ethanol‐selective pervaporation…”
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Unzipping the Secrets of Amyloid Disassembly by the Human Disaggregase by Franco, Aitor, Velasco-Carneros, Lorea, Alvarez, Naiara, Orozco, Natalia, Moro, Fernando, Prado, Adelina, Muga, Arturo

“…Neurodegenerative diseases (NDs) are increasingly positioned as leading causes of global deaths. The accelerated aging of the population and its strong…”
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Deletion of TAK1 in the myeloid lineage results in the spontaneous development of myelomonocytic leukemia in mice by Lamothe, Betty, Lai, Yunju, Hur, Lana, Orozco, Natalia Martin, Wang, Jing, Campos, Alejandro D, Xie, Min, Schneider, Michael D, Lockworth, Cynthia R, Jakacky, Jared, Tran, Diep, Ho, Michael, Dawud, Sity, Dong, Chen, Lin, Hui-Kuan, Hu, Peter, Estrov, Zeev, Bueso-Ramos, Carlos E, Darnay, Bryant G

“…Previous studies of the conditional ablation of TGF-β activated kinase 1 (TAK1) in mice indicate that TAK1 has an obligatory role in the survival and/or…”
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Comparable safety and non-inferior immunogenicity of the SARS-CoV-2 mRNA vaccine candidate PTX-COVID19-B and BNT162b2 in a phase 2 randomized, observer-blinded study by Reiter, Lawrence, Greffrath, Johann, Zidel, Bian, Ostrowski, Mario, Gommerman, Jennifer, Madhi, Shabir A., Tran, Richard, Martin-Orozco, Natalia, Panicker, Rajesh Krishnan Gopalakrishna, Cooper, Curtis, Pastrak, Aleksandra

“…In the aftermath of the COVID-19 pandemic, the evolution of the SARS-CoV-2 into a seasonal pathogen along with the emergence of new variants, underscores the…”
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CD226 and TIGIT Cooperate in the Differentiation and Maturation of Human Tfh Cells by Yasutomi, Motoko, Christiaansen, Allison F, Imai, Naoko, Martin-Orozco, Natalia, Forst, Christian V, Chen, Gang, Ueno, Hideki

“…Costimulation pathways play an essential role in T cell activation, differentiation, and regulation. CD155 expressed on antigen-presenting cells (APCs)…”
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Phase I randomized, observer-blinded, placebo-controlled study of a SARS-CoV-2 mRNA vaccine PTX-COVID19-B by Martin-Orozco, Natalia, Vale, Noah, Mihic, Alan, Amor, Talya, Reiter, Lawrence, Arita, Yuko, Samson, Reuben, Hu, Queenie, Gingras, Anne-Claude, Sorenson, Bradley Thomas, Marcusson, Eric Gates, Patel, Piyush

“…Access to vaccines against SARS-CoV-2 virus was limited in poor countries during the COVID-19 pandemic. Therefore, a low-cost mRNA vaccine, PTX-COVID19-B, was…”
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Molecular and morphologic characterization of Sarcocystis felis (Apicomplexa: Sarcocystidae) in South American wild felids from Brazil by Cañón-Franco, William Alberto, López-Orozco, Natalia, Christoff, Alexandre Uarth, de Castilho, Camila Schlieper, de Araújo, Flavio Antônio Pacheco, Verma, Shiv Kumar, Dubey, J.P., Soares, Rodrigo Martins, Gennari, Solange Maria

“…•Sarcocystis felis DNA was detected in tissue of five small wild felids species; Puma yagouaroundi, Leopardus colocolo, L. geoffroyi, L. guttulus, and L…”
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Proton Pump Inhibitors. Investigating Their Role in Small Intestinal Bacterial Overgrowth by Kruszewski, Adrian, Szyszka, Monika, Kucharska, Maja, Przybysz, Paulina, Kwiliński, Kacper, Wawrzyńska, Barbara, Rydlakowska-Orozco, Natalia

“…Proton pump inhibitors (PPIs) are widely used medications known for their effectiveness in reducing gastric acid production and their overall safety profile…”
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Defective positive selection results in T cell lymphopenia and increased autoimmune diabetes in ADAP-deficient BDC2.5-C57BL/6 mice by Zou, Liangxing, Mendez, Felipe, Martin-Orozco, Natalia, Peterson, Erik J

“…Adhesion and degranulation promoting adapter protein (ADAP), a positive regulator of T cell receptor (TCR) signaling, is required for thymocyte development and…”
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Reflexiones trans para la educación descolonizadora de / mediante los estudios literarios en la educación general by Santos Orozco, Natalia

“…En este artículo se explora la función de los estudios literarios en y para la educación general desde la perspectiva de una pedagogía crítica y…”
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Phoretic mites identified on Andean hummingbirds (Trochilidae) of Caldas, Colombia by López-Orozco, Natalia, Cañón-Franco, William Alberto

“…Within the bird-plant-mite system, the relationship between hummingbirds, flowers, and mites remains poorly understood. In this study, we evaluated the degree…”
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