Search Results - "Orom, Ulf Andersson"

Gene Expression Profiling Reveals a Signaling Role of Glutathione in Redox Regulation by Fratelli, Maddalena, Goodwin, Leslie O., Ørom, Ulf Andersson, Lombardi, Sarah, Tonelli, Rossella, Mengozzi, Manuela, Ghezzi, Pietro, Dinarello, Charles A.

“…Proteins can form reversible mixed disulfides with glutathione (GSH). It has been hypothesized that protein glutathionylation may represent a mechanism of…”
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Long Noncoding RNAs Usher In a New Era in the Biology of Enhancers by Ørom, Ulf Andersson, Shiekhattar, Ramin

“…Enhancer-associated long noncoding RNAs act over long distances and across chromosomes to activate transcription at distal promoters. Here, we address the…”
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Recent progress in miRNA biogenesis and decay by Bofill-De Ros, Xavier, Vang Ørom, Ulf Andersson

“…MicroRNAs are a class of small regulatory RNAs that mediate regulation of protein synthesis by recognizing sequence elements in mRNAs. MicroRNAs are processed…”
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Microprocessor Activity Controls Differential miRNA Biogenesis In Vivo by Conrad, Thomas, Marsico, Annalisa, Gehre, Maja, Ørom, Ulf Andersson

“…In miRNA biogenesis, pri-miRNA transcripts are converted into pre-miRNA hairpins. The in vivo properties of this process remain enigmatic. Here, we determine…”
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Serial interactome capture of the human cell nucleus by Conrad, Thomas, Albrecht, Anne-Susann, de Melo Costa, Veronica Rodrigues, Sauer, Sascha, Meierhofer, David, Ørom, Ulf Andersson

“…Novel RNA-guided cellular functions are paralleled by an increasing number of RNA-binding proteins (RBPs). Here we present ‘serial RNA interactome capture’…”
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Noncoding RNAs and enhancers: complications of a long-distance relationship by Ørom, Ulf Andersson, Shiekhattar, Ramin

“…Spatial and temporal regulation of gene expression is achieved through instructions provided by the distal transcriptional regulatory elements known as…”
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LincRNA H19 protects from dietary obesity by constraining expression of monoallelic genes in brown fat by Schmidt, Elena, Dhaouadi, Ines, Gaziano, Isabella, Oliverio, Matteo, Klemm, Paul, Awazawa, Motoharu, Mitterer, Gerfried, Fernandez-Rebollo, Eduardo, Pradas-Juni, Marta, Wagner, Wolfgang, Hammerschmidt, Philipp, Loureiro, Rute, Kiefer, Christoph, Hansmeier, Nils R., Khani, Sajjad, Bergami, Matteo, Heine, Markus, Ntini, Evgenia, Frommolt, Peter, Zentis, Peter, Ørom, Ulf Andersson, Heeren, Jörg, Blüher, Matthias, Bilban, Martin, Kornfeld, Jan-Wilhelm

“…Increasing brown adipose tissue (BAT) thermogenesis in mice and humans improves metabolic health and understanding BAT function is of interest for novel…”
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Predicting nuclear G-quadruplex RNA-binding proteins with roles in transcription and phase separation by Luige, Johanna, Armaos, Alexandros, Tartaglia, Gian Gaetano, Ørom, Ulf Andersson Vang

“…RNA-binding proteins are central for many biological processes and their characterization has demonstrated a broad range of functions as well as a wide…”
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Isolation of microRNA targets using biotinylated synthetic microRNAs by Ørom, Ulf Andersson, Lund, Anders H.

“…MicroRNAs are small regulatory RNAs found in multicellular organisms where they post-transcriptionally regulate gene expression. In animals, microRNAs bind…”
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Long ncRNA A-ROD activates its target gene DKK1 at its release from chromatin by Ntini, Evgenia, Louloupi, Annita, Liz, Julia, Muino, Jose M., Marsico, Annalisa, Ørom, Ulf Andersson Vang

“…Long ncRNAs are often enriched in the nucleus and at chromatin, but whether their dissociation from chromatin is important for their role in transcription…”
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miR-200b mediates post-transcriptional repression of ZFHX1B by Christoffersen, Nanna Rønbjerg, Silahtaroglu, Asli, Orom, Ulf Andersson, Kauppinen, Sakari, Lund, Anders H

“…MicroRNAs have important functions during animal development and homeostasis through post-transcriptional regulation of their cognate mRNA targets. ZFHX1B is a…”
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Bidirectional expression of long ncRNA/protein-coding gene pairs in cancer by Albrecht, Anne-Susann, Ørom, Ulf Andersson

“…Bidirectional initiation of transcription by RNA polymerase II occurs prevalently at active promoters during protein-coding gene (PCG) expression. Upstream,…”
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Microprocessor Activity Controls Differential miRNA Biogenesis In Vivo by Conrad, Thomas, Marsico, Annalisa, Gehre, Maja, Ørom, Ulf Andersson

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MicroRNA-203 regulates caveolin-1 in breast tissue during caloric restriction by Ørom, Ulf Andersson, Lim, Meng K., Savage, Jason E., Jin, Lianjin, Saleh, Anthony D., Lisanti, Michael P., Simone, Nicole L.

“…Caloric restriction has been shown to increase lifespan in several organisms and to delay onset of age-related diseases. The transcriptional response to…”
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MicroRNA-10a Binds the 5′UTR of Ribosomal Protein mRNAs and Enhances Their Translation by Ørom, Ulf Andersson, Nielsen, Finn Cilius, Lund, Anders H.

“…MicroRNAs (miRNAs) are small RNAs that function as posttranscriptional regulators of gene expression. miRNAs affect a variety of signaling pathways, and…”
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Long non-coding RNAs and enhancers by Ørom, Ulf Andersson, Shiekhattar, Ramin

“…Long non-coding RNAs (ncRNAs) are emerging as important regulatory factors in mammalian genomics. A number of reports within the last 2 years have identified…”
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Long Noncoding RNAs with Enhancer-like Function in Human Cells by Ørom, Ulf Andersson, Derrien, Thomas, Beringer, Malte, Gumireddy, Kiranmai, Gardini, Alessandro, Bussotti, Giovanni, Lai, Fan, Zytnicki, Matthias, Notredame, Cedric, Huang, Qihong, Guigo, Roderic, Shiekhattar, Ramin

“…While the long noncoding RNAs (ncRNAs) constitute a large portion of the mammalian transcriptome, their biological functions has remained elusive. A few long…”
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Cellular Fractionation and Isolation of Chromatin-Associated RNA by Conrad, Thomas, Ørom, Ulf Andersson

“…In eukaryotic cells, the synthesis, processing, and functions of RNA molecules are confined to distinct subcellular compartments. Biochemical fractionation of…”
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N4-acetylcytidine (ac4C) promotes mRNA localization to stress granules by Kudrin, Pavel, Singh, Ankita, Meierhofer, David, Kuśnierczyk, Anna, Ørom, Ulf Andersson Vang

“…Stress granules are an integral part of the stress response that are formed from non-translating mRNAs aggregated with proteins. While much is known about…”
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The Non-Coding RNA Journal Club: Highlights on Recent Papers-7 by Xiao, Hua, Shiu, Patrick K T, Gabryleska, Marta, Conn, Simon J, Dey, Abhishek, Chakrabarti, Kausik, Regouc, Manuel, Pichler, Martin, Ørom, Ulf Andersson Vang, Santulli, Gaetano, Nishiwada, Satoshi, Goel, Ajay, Nagarajan, Vaishnavi, Timmons, Lisa, Alahari, Suresh K, Laprovitera, Noemi, Ferracin, Manuela, Hu, Po, Jin, Hailing

“…We are delighted to share with you our seventh Journal Club and highlight some of the most interesting papers published recently [...]…”
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