Search Results - "Ornoy, A"

Valproic acid in pregnancy: How much are we endangering the embryo and fetus? by Ornoy, Asher

“…Valproic acid (VPA) is a known human teratogen. Exposure in pregnancy is associated with approximately three-fold increase in the rate of major anomalies,…”
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Prenatal factors associated with autism spectrum disorder (ASD) by Ornoy, A., Weinstein-Fudim, L., Ergaz, Z.

“…Autism spectrum disorder (ASD) affecting about 1% of all children is associated, in addition to complex genetic factors, with a variety of prenatal, perinatal…”
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The impact of intrauterine exposure versus postnatal environment in neurodevelopmental toxicity: long-term neurobehavioral studies in children at risk for developmental disorders by Ornoy, A

“…Various investigators have shown that enriched environment may positively affect the early brain development of experimental animals. Environment was also…”
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Integrin α2β1 plays a critical role in osteoblast response to micron-scale surface structure and surface energy of titanium substrates by Olivares-Navarrete, R, Raz, P, Zhao, G, Chen, J, Wieland, M, Cochran, D.L, Chaudhri, R.A, Ornoy, A, Boyan, B.D, Schwartz, Z

“…Efforts to improve bone response to biomaterials have focused on ligands that bind α5β1 integrins. However, antibodies to α5β1 reduce osteoblast proliferation…”
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Integrin alpha 2 beta 1 plays a critical role in osteoblast response to micron-scale surface structure and surface energy of titanium substrates by Olivares-Navarrete, R, Raz, P, Zhao, G, Chen, J, Wieland, M, Cochran, D L, Chaudhri, R A, Ornoy, A, Boyan, B D, Schwartz, Z

“…Efforts to improve bone response to biomaterials have focused on ligands that bind alpha 5 beta 1 integrins. However, antibodies to alpha 5 beta 1 reduce…”
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Fetal effects of primary and secondary cytomegalovirus infection in pregnancy by Ornoy, Asher, Diav-Citrin, Orna

“…Seroconversion to cytomegalovirus (CMV) occurs in 1–4% of pregnant women. The majority of these women are seropositive prior to pregnancy. In 0.2–2.5% of the…”
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Expert consensus on neurodevelopmental outcomes in pregnancy pharmacovigilance studies by Bromley, R L, Bickle Graz, M, Bluett-Duncan, M, Chambers, C, Damkier, P, Dietrich, K, Dolk, H, Grant, K, Mattson, S, Meador, K J, Nordeng, H, Oberlander, T F, Ornoy, A, Revet, A, Richardson, J, Rovet, J, Schuler-Faccini, L, Smearman, E, Simms, V, Vorhees, C, Wide, K, Wood, A, Yates, L, Ystrom, E, Supraja, T A, Adams, J

“…Exposure to certain medications can disrupt processes of fetal development, including brain development, leading to a continuum of neurodevelopmental…”
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Postpartum depression and infant development up to 24 months: A nationwide population-based study by Lubotzky-Gete, S., Ornoy, A., Grotto, I, Calderon-Margalit, R.

“…•Only few studies have investigated the associations between postpartum depression (PPD) and child development. Most of these studies were limited in size,…”
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Pregnancy outcome following infections by coxsackie, echo, measles, mumps, hepatitis, polio and encephalitis viruses by Ornoy, Asher, Tenenbaum, Alexander

“…Women may be infected during pregnancy with infectious agents that are often passed unnoticed; however, the causative agent may still traverse the placenta and…”
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The teratogenic effect of carbamazepine: a meta-analysis of 1255 exposures by Matalon, S, Schechtman, S, Goldzweig, G, Ornoy, A

“…Maternal use of antiepileptic drugs during pregnancy has been associated with an increased risk of major congenital abnormalities in the fetus. Carbamazepine…”
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Genetic and teratogenic effects of cancer treatments on gametes and embryos by Arnon, J., Meirow, D., Lewis-Roness, H., Ornoy, A.

“…Male and female germ cells vary in their sensitivity to the mutagenic effects of chemotherapy and radiotherapy, depending on their stage of maturation and the…”
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The safety of proton pump inhibitors in pregnancy: a multicentre prospective controlled study by Diav‐Citrin, O., Arnon, J., Shechtman, S., Schaefer, C., Tonningen, M. R., Clementi, M., Santis, M., Robert‐Gnansia, E., Valti, E., Malm, H., Ornoy, A.

“…Summary Background : Proton pump inhibitors are used to treat gastro‐oesophageal reflux and peptic ulcers. Gastro‐oesophageal reflux is a common condition in…”
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Outcome of children born to epileptic mothers treated with carbamazepine during pregnancy by Ornoy, A, Cohen, E

“…AIM: The purpose of the study was to assess whether there was an increased rate of congenital anomalies or significant developmental delay in infants of women…”
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The Role of heat shock protein 27 in extravillous trophoblast differentiation by Matalon, S. Tartakover, Drucker, L., Fishman, A., Ornoy, A., Lishner, M.

“…Trophoblast cells from placental explants differentiate in culture to extravillous trophoblast cells (EVT cells). During trophoblast differentiation…”
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Is carbamazepine teratogenic? A prospective controlled study of 210 pregnancies by DIAV-CITRIN, Orna, SHECHTMAN, Svetlana, ARNON, Judy, ORNOY, Asher

“…The Israeli Teratogen Information Service prospectively followed up 210 pregnancies with first trimester carbamazepine exposure. Pregnancy outcome was compared…”
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Intrauterine infections: Introductory comments by ORNOY, A

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The Association Between Anti-Thyroid Antibodies and Pregnancy Loss by MATALON, S. T., BLANK, M., ORNOY, A., SHOENFELD, Y.

“…The incidence of thyroid autoantibodies in women with recurrent fetal loss, infertility or women who miscarried appears to be increased compared with controls…”
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Embryonic oxidative stress as a mechanism of teratogenesis with special emphasis on diabetic embryopathy by Ornoy, Asher

“…Reactive oxygen species (ROS) are involved in the etiology of numerous diseases including cardio-vascular diseases and diabetes mellitus. There is evidence…”
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School-age children born to diabetic mothers and to mothers with gestational diabetes exhibit a high rate of inattention and fine and gross motor impairment by Ornoy, A, Ratzon, N, Greenbaum, C, Wolf, A, Dulitzky, M

“…To study the neurobehavioral effects that pregestational and gestational diabetes might have on offspring at school age. We studied neurobehavioral function at…”
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The pathogenic role of anti‐thyroglobulin antibody on pregnancy: evidence from an active immunization model in mice by Matalon, Shelly Tartakover, Blank, Miri, Levy, Yair, Carp, Howard J.A., Arad, Ayala, Burek, Lynne, Grunebaum, Eyal, Sherer, Yaniv, Ornoy, Asher, Refetoff, Samuel, Weiss, Roy E., Rose, Noel R., Shoenfeld, Yehuda

“…BACKGROUND: The presence of antibodies to thyroglobulin (Tg) is associated with fetal loss even in the absence of thyroid dysfunction. The aim of this study…”
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