Search Results - "Ornella Parolini"

Is Immune Modulation the Mechanism Underlying the Beneficial Effects of Amniotic Cells and Their Derivatives in Regenerative Medicine? by Silini, Antonietta R., Magatti, Marta, Cargnoni, Anna, Parolini, Ornella

“…Regenerative medicine aims to repair and regenerate damaged cells, tissues, and organs in order to restore function. Regeneration can be obtained either by…”
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Human Amniotic Membrane-Derived Mesenchymal and Epithelial Cells Exert Different Effects on Monocyte-Derived Dendritic Cell Differentiation and Function by Magatti, Marta, Caruso, Maddalena, De Munari, Silvia, Vertua, Elsa, De, Debashree, Manuelpillai, Ursula, Parolini, Ornella

“…We previously demonstrated that mesenchymal cells from human amniotic membrane (hAMTCs) inhibit the generation and maturation of monocyte-derived dendritic…”
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Characterization of the conditioned medium from amniotic membrane cells: prostaglandins as key effectors of its immunomodulatory activity by Rossi, Daniele, Pianta, Stefano, Magatti, Marta, Sedlmayr, Peter, Parolini, Ornella

“…We previously demonstrated that cells isolated from the mesenchymal region of the human amniotic membrane (human amniotic mesenchymal tissue cells, hAMTC)…”
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Shaping modern human skull through epigenetic, transcriptional and post-transcriptional regulation of the RUNX2 master bone gene by Di Pietro, Lorena, Barba, Marta, Palacios, Daniela, Tiberio, Federica, Prampolini, Chiara, Baranzini, Mirko, Parolini, Ornella, Arcovito, Alessandro, Lattanzi, Wanda

“…RUNX2 encodes the master bone transcription factor driving skeletal development in vertebrates, and playing a specific role in craniofacial and skull…”
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Fibrin Scaffolds Perfused with Transforming Growth Factor-β1 as an In Vitro Model to Study Healthy and Tendinopathic Human Tendon Stem/Progenitor Cells by Ciardulli, Maria Camilla, Lovecchio, Joseph, Parolini, Ornella, Giordano, Emanuele, Maffulli, Nicola, Della Porta, Giovanna

“…A limited understanding of tendon cell biology in healthy and pathological conditions has impeded the development of effective treatments, necessitating in…”
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Altered Expression of Autophagy Biomarkers in Hippocampal Neurons in a Multiple Sclerosis Animal Model by Ceccariglia, Sabrina, Sibilia, Diego, Parolini, Ornella, Michetti, Fabrizio, Di Sante, Gabriele

“…Multiple Sclerosis (MS) is a chronic inflammatory disease that affects the brain and spinal cord. Inflammation, demyelination, synaptic alteration, and…”
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In Utero Hematopoietic Stem-Cell Transplantation — A Match for Mom by Parolini, Ornella

“…Engraftment of transplanted hematopoietic stem cells in the developing fetus is achieved with variable rates of success. A recent study suggests that immune…”
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Nano-Immunomodulation: A New Strategy for Skeletal Muscle Diseases and Aging? by Millozzi, Francesco, Papait, Andrea, Bouché, Marina, Parolini, Ornella, Palacios, Daniela

“…The skeletal muscle has a very remarkable ability to regenerate upon injury under physiological conditions; however, this regenerative capacity is strongly…”
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Transplantation of allogeneic and xenogeneic placenta-derived cells reduces bleomycin-induced lung fibrosis by Cargnoni, Anna, Gibelli, Lucia, Tosini, Alessandra, Signoroni, Patrizia Bonassi, Nassuato, Claudia, Arienti, Davide, Lombardi, Guerino, Albertini, Alberto, Wengler, Georg S, Parolini, Ornella

“…Fetal membranes (amnion and chorion) have recently raised significant attention as potential sources of stem cells. We have recently demonstrated that cells…”
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B Lymphocytes as Targets of the Immunomodulatory Properties of Human Amniotic Mesenchymal Stromal Cells by Magatti, Marta, Masserdotti, Alice, Bonassi Signoroni, Patrizia, Vertua, Elsa, Stefani, Francesca Romana, Silini, Antonietta Rosa, Parolini, Ornella

“…Mesenchymal stromal cells (MSC) from the amniotic membrane of human term placenta (hAMSC), and the conditioned medium generated from their culture (CM-hAMSC)…”
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Clinical Application of Adipose Derived Stem Cells for the Treatment of Aseptic Non-Unions: Current Stage and Future Perspectives-Systematic Review by Smakaj, Amarildo, De Mauro, Domenico, Rovere, Giuseppe, Pietramala, Silvia, Maccauro, Giulio, Parolini, Ornella, Lattanzi, Wanda, Liuzza, Francesco

“…Fracture non-union is a challenging orthopaedic issue and a socio-economic global burden. Several biological therapies have been introduced to improve…”
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Graphene Quantum Dots' Surface Chemistry Modulates the Sensitivity of Glioblastoma Cells to Chemotherapeutics by Perini, Giordano, Palmieri, Valentina, Ciasca, Gabriele, D'Ascenzo, Marcello, Gervasoni, Jacopo, Primiano, Aniello, Rinaldi, Monica, Fioretti, Daniela, Prampolini, Chiara, Tiberio, Federica, Lattanzi, Wanda, Parolini, Ornella, De Spirito, Marco, Papi, Massimiliano

“…Recent evidence has shown that graphene quantum dots (GQDs) are capable of crossing the blood-brain barrier, the barrier that reduces cancer therapy efficacy…”
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The evolution of in vitro models of lung fibrosis: promising prospects for drug discovery by Kolanko, Emanuel, Cargnoni, Anna, Papait, Andrea, Silini, Antonietta Rosa, Czekaj, Piotr, Parolini, Ornella

“…Lung fibrosis is a complex process, with unknown underlying mechanisms, involving various triggers, diseases and stimuli. Different cell types (epithelial…”
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Amniotic membrane‐mesenchymal stromal cells secreted factors and extracellular vesicle‐miRNAs: Anti‐inflammatory and regenerative features for musculoskeletal tissues by Ragni, Enrico, Papait, Andrea, Perucca Orfei, Carlotta, Silini, Antonietta Rosa, Colombini, Alessandra, Viganò, Marco, Libonati, Francesca, Parolini, Ornella, Girolamo, Laura

“…Human amniotic membrane‐derived mesenchymal stromal cells (hAMSCs) are easily obtained in large quantities and free from ethical concerns. Promising…”
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Placental Cells and Derivatives by Silini, Antonietta R, Parolini Ornella

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Mesenchymal Stromal Cells and Their Secretome: New Therapeutic Perspectives for Skeletal Muscle Regeneration by Sandonà, Martina, Di Pietro, Lorena, Esposito, Federica, Ventura, Alessia, Silini, Antonietta Rosa, Parolini, Ornella, Saccone, Valentina

“…Mesenchymal stromal cells (MSCs) are multipotent cells found in different tissues: bone marrow, peripheral blood, adipose tissues, skeletal muscle, perinatal…”
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Amniotic mesenchymal tissue cells inhibit dendritic cell differentiation of peripheral blood and amnion resident monocytes by Magatti, Marta, De Munari, Silvia, Vertua, Elsa, Nassauto, Claudia, Albertini, Alberto, Wengler, Georg S, Parolini, Ornella

“…Cells derived from the amniotic membranes of human term placenta have drawn much interest for their characteristics of multipotency and low immunogenicity,…”
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Amniotic Membrane-Derived Stromal Cells Release Extracellular Vesicles That Favor Regeneration of Dystrophic Skeletal Muscles by Sandonà, Martina, Esposito, Federica, Cargnoni, Anna, Silini, Antonietta, Romele, Pietro, Parolini, Ornella, Saccone, Valentina

“…Duchenne muscular dystrophy (DMD) is a muscle disease caused by mutations in the dystrophin gene characterized by myofiber fragility and progressive muscle…”
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Concise Review: Isolation and Characterization of Cells from Human Term Placenta: Outcome of the First International Workshop on Placenta Derived Stem Cells by Parolini, Ornella, Alviano, Francesco, Bagnara, Gian Paolo, Bilic, Grozdana, Bühring, Hans‐Jörg, Evangelista, Marco, Hennerbichler, Simone, Liu, Bing, Magatti, Marta, Mao, Ning, Miki, Toshio, Marongiu, Fabio, Nakajima, Hideaki, Nikaido, Toshio, Portmann‐Lanz, C. Bettina, Sankar, Venkatachalam, Soncini, Maddalena, Stadler, Guido, Surbek, Daniel, Takahashi, Tsuneo A., Redl, Heinz, Sakuragawa, Norio, Wolbank, Susanne, Zeisberger, Steffen, Zisch, Andreas, Strom, Stephen C.

“…Placental tissue draws great interest as a source of cells for regenerative medicine because of the phenotypic plasticity of many of the cell types isolated…”
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Comparison of EV-free fraction, EVs, and total secretome of amniotic mesenchymal stromal cells for their immunomodulatory potential: a translational perspective by Papait, Andrea, Ragni, Enrico, Cargnoni, Anna, Vertua, Elsa, Romele, Pietro, Masserdotti, Alice, Perucca Orfei, Carlotta, Signoroni, Patrizia Bonassi, Magatti, Marta, Silini, Antonietta R., De Girolamo, Laura, Parolini, Ornella

“…Amniotic mesenchymal stromal cells (hAMSCs) have unique immunomodulatory properties demonstrated in vitro and in vivo in various diseases in which the…”
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