Search Results - "Orndorff, Keely"

Structural Basis for the Interaction Between Yeast Chromatin Assembly Factor 1 and Proliferating Cell Nuclear Antigen by Orndorff, Keely S., Veltri, Evan J., Hoitsma, Nicole M., Williams, Ivy L., Hall, Ian, Jaworski, Grace E., Majeres, Grace E., Kallepalli, Samaya, Vito, Abigayle F., Struble, Lucas R., Borgstahl, Gloria E.O., Dieckman, Lynne M.

“…[Display omitted] •How does PCNA choose who to bind (via PIP motifs) at the replication fork?•Development of a novel method for determining structures of…”
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STEM-20. REGULATION OF GLIOMA STEM CELL MAINTENANCE AND THERAPEUTIC RESISTANCE BY EGFR MISSENSE MUTATIONS by Weaver, Sidney, Miller, Aunay, Blomquist, Mylan, McNamara, James, Orndorff, Keely, Kloss, Jean, Sereduk, Christopher, Loftus, Joseph, Mehta, Shwetal, Tran, Nhan

“…Abstract Glioblastoma (GBM) tumors contain a subpopulation of glioma stem cells (GSC) which can escape therapeutic effects through self-renewal and invasion…”
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EXTH-50. ACUTE AND LONG-TERM RESPONSES TO QUISINOSTAT TREATMENT IN PDX MODELS OF GLIOBLASTOMA by Orndorff, Keely, McNamara, James, LoCascio, Costanza, White, Connor, Stavnichuk, Mariya, Shaik, Kamal, Margaryan, Tigran, Tovmasyan, Artak, Sanai, Nader, Mehta, Shwetal

“…Abstract BACKGROUND Histone deacetylase inhibitors (HDACi) promote reactive oxygen species production, result in DNA damage, and trigger cell fate changes…”
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STEM-15. STAT5-OLIG2 TRANSCRIPTIONAL COMPLEX MEDIATES GLIOMA STEM CELL SELF RENEWAL AND INVASION by Miller, Aunay, Cascio, Costanza Lo, Blomquist, Mylan, McNamara, James, Orndorff, Keely, Dufault, Matthew, Sereduk, Christopher, Loftus, Joseph, Mehta, Shwetal, Tran, Nhan

“…Abstract Glioblastoma (GBM) is the most common and lethal primary brain tumor in adults, despite current treatment options. One of the major contributing…”
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Abstract 3222: Acute and long-term responses to treatment with the HDAC inhibitor quisinostat in preclinical models of glioblastoma by Orndorff, Keely, McNamara, James, Stavnichuk, Mariya, Cascio, Costanza Lo, White, Connor, Melendez, Ernesto Luna, Uzunalli, Gozde, Sanai, Nader, Mehta, Shwetal

“…Abstract Introduction: High expression of histone deacetylases (HDACs), particularly HDAC1, is strongly associated with poor prognosis for glioblastoma (GBM)…”
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Abstract 5444: EGFR missense mutation(s) induce OLIG2 expression to regulate glioma stem cells maintenance and therapeutic resistance by Weaver, Sidney, Miller, Aunay, Blomquist, Mylan, McNamara, James, Orndorff, Keely, Sereduk, Chris, Kloss, Jean, Loftus, Joseph, Mehta, Shwetal, Tran, Nhan L.

“…Abstract Glioblastoma (GBM) tumors contain a subpopulation of glioma stem cells (GSC) which can escape therapeutic effects through self-renewal and invasion…”
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Abstract 256: A novel transcriptional complex of OLIG2-STAT5 mediates glioma stem cell self renewal and invasion by Miller, Aunay, Lo Cascio, Costanza, Blomquist, Mylan, McNamara, James B., Orndorff, Keely, Dufault, Matthew, Sereduk, Christopher, Loftus, Joseph, Mehta, Shwetal, Tran, Nhan L.

“…Abstract Glioblastoma (GBM) is the most common and lethal primary brain tumor in adults, despite current treatment options. One of the major contributing…”
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