Search Results - "Ornatsky, Olga I"

Imaging Mass Cytometry by Chang, Qing, Ornatsky, Olga I., Siddiqui, Iram, Loboda, Alexander, Baranov, Vladimir I., Hedley, David W.

“…Imaging Mass Cytometry (IMC) is an expansion of mass cytometry, but rather than analyzing single cells in suspension, it uses laser ablation to generate plumes…”
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Mass Cytometry: Technique for Real Time Single Cell Multitarget Immunoassay Based on Inductively Coupled Plasma Time-of-Flight Mass Spectrometry by Bandura, Dmitry R, Baranov, Vladimir I, Ornatsky, Olga I, Antonov, Alexei, Kinach, Robert, Lou, Xudong, Pavlov, Serguei, Vorobiev, Sergey, Dick, John E, Tanner, Scott D

“…A novel instrument for real time analysis of individual biological cells or other microparticles is described. The instrument is based on inductively coupled…”
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Single-Cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum by Bendall, Sean C., Simonds, Erin F., Qiu, Peng, Amir, El-ad D., Krutzik, Peter O., Finck, Rachel, Bruggner, Robert V., Melamed, Rachel, Trejo, Angelica, Ornatsky, Olga I., Balderas, Robert S., Plevritis, Sylvia K., Sachs, Karen, Pe'er, Dana, Tanner, Scott D., Nolan, Garry P.

“…Flow cytometry is an essential tool for dissecting the functional complexity of hematopoiesis. We used single-cell "mass cytometry" to examine healthy human…”
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An introduction to mass cytometry: fundamentals and applications by Tanner, Scott D., Baranov, Vladimir I., Ornatsky, Olga I., Bandura, Dmitry R., George, Thaddeus C.

“…Mass cytometry addresses the analytical challenges of polychromatic flow cytometry by using metal atoms as tags rather than fluorophores and atomic mass…”
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Biodistribution of cisplatin revealed by imaging mass cytometry identifies extensive collagen binding in tumor and normal tissues by Chang, Qing, Ornatsky, Olga I., Siddiqui, Iram, Straus, Rita, Baranov, Vladimir I., Hedley, David W.

“…Imaging mass cytometry was used for direct visualization of platinum localization in tissue sections from tumor and normal tissues of cisplatin-treated mice…”
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Enabling Indium Channels for Mass Cytometry by Using Reinforced Cyclam-Based Chelating Polylysine by Grenier, Laura, Beyler, Maryline, Closson, Taunia, Zabinyakov, Nick, Bouzekri, Alexandre, Zhang, Yefeng, Pichaandi, Jothir Mayanantham, Winnik, Mitchell A, Liu, Peng, Ornatsky, Olga I, Baranov, Vladimir, Tripier, Raphaël

“…The synthesis of a polylysine polymer functionalized with the previously reported astonishingly inert [In­(cb-te2pa)]+ chelate was performed. A biotin end…”
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Highly Stable and Inert Complexation of Indium(III) by Reinforced Cyclam Dipicolinate and a Bifunctional Derivative for Bead Encoding in Mass Cytometry by Grenier, Laura, Beyler, Maryline, Platas‐Iglesias, Carlos, Closson, Taunia, Gómez, David Esteban, Seferos, Dwight S., Liu, Peng, Ornatsky, Olga I., Baranov, Vladimir, Tripier, Raphaël

“…H2cb‐te2pa, a cross‐bridged cyclam functionalized by two picolinate arms, was used for the formation of an incredible inert InIII chelate. The inertness of the…”
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Single‐cell measurement of the uptake, intratumoral distribution and cell cycle effects of cisplatin using mass cytometry by Chang, Qing, Ornatsky, Olga I., Koch, Cameron J., Chaudary, Naz, Marie‐Egyptienne, Delphine T., Hill, Richard P., Tanner, Scott D., Hedley, David W.

“…Although of fundamental importance to the treatment of cancer patients, the quantitative study of drug distribution and action in vivo at the single cell level…”
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A Dominant-Negative Form of Transcription Factor MEF2 Inhibits Myogenesis by Ornatsky, Olga I., Andreucci, John J., McDermott, John C.

“…A biological role for MEF2 (myocyteenhancer factor 2) activity during mammalian myogenesis has been inferred but not directly proven because of its role in the…”
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Post-translational control of the MEF2A transcriptional regulatory protein by Ornatsky, Olga I., Cox, David M., Tangirala, Padma, Andreucci, John J., Quinn, Zoë A., Wrana, Jeffrey L., Prywes, Ron, Yu, Yie-Teh, McDermott, John C.

“…Myocyte enhancer factor 2 (MEF2) transcriptional regulatory proteins are key regulators of muscle-specific gene expression and also play a general role in the…”
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MEF2 Protein Expression, DNA Binding Specificity and Complex Composition, and Transcriptional Activity in Muscle and Non-muscle Cells by Ornatsky, O I, McDermott, J C

“…Tissue-specific gene expression can be mediated by complex transcriptional regulatory mechanisms. Based on the dichotomy of the ubiquitous distribution of the…”
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Abstract 1667: A robust human immune profiling assay using CyTOF technology and automated data analysis software by Li, Stephen K., Majonis, Daniel, Bagwell, C. Bruce, Hunsberger, Benjamin C., Baranov, Vladimir I., Ornatsky, Olga I.

“…Immune monitoring is an essential method for quantifying changes in immune cell population numbers and states over time in health and disease. A cornerstone in…”
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Messenger RNA Detection in Leukemia Cell lines by Novel Metal-Tagged in situ Hybridization using Inductively Coupled Plasma Mass Spectrometry by Ornatsky, Olga I, Baranov, Vladimir I, Bandura, Dmitry R, Tanner, Scott D, Dick, John

“…Conventional gene expression profiling relies on using fluorescent detection of hybridized probes. Physical characteristics of fluorophores impose limitations…”
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Mitochondrial biogenesis during pressure overload induced cardiac hypertrophy in adult rats by Nishio, M L, Ornatsky, O I, Craig, E E, Hood, D A

“…Existing literature provides an equivocal picture of the behavior of mitochondrial synthesis during the time course of cardiac hypertrophy. Therefore, we…”
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Mass Cytometry: Technique for Real Time Single Cell Multitarget Immunoassay Based on Inductively Coupled Plasma Time-of-Flight Mass Spectrometry by Bandura, Dmitry R, Baranov, Vladimir I, Ornatsky, Olga I, Antonov, Alexei, Kinach, Robert, Lou, Xudong, Pavlov, Serguei, Vorobiev, Sergey, Dick, John E, Tanner, Scott D

“…A novel instrument for real time analysis of individual biological cells or other microparticles is described. The instrument is based on inductively coupled…”
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Interaction of myocyte enhancer factor 2 (MEF2) with a mitogen-activated protein kinase, ERK5/BMK1 by Yang, Chih-Chin, Ornatsky, Olga I., McDermott, John C., Cruz, Tony F., Prody, Catherine A.

“…Myocyte enhancer factor 2 (MEF2) has been implicated in the complex hierarchical regulation of muscle-specific gene expression and differentiation. While the…”
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Multiplex Biomarker Detection by ICP‐MS by Ornatsky, Olga I, Baranov, Vladimir, Bandura, Dmitry, Tanner, Scott, Dick, John

“…A novel application of ICP‐MS to cell biology is presented. This work details a method of multiplex cellular antigen determination using ICP‐MS‐linked…”
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Molecular cloning of up-regulated cytoskeletal genes from regenerating skeletal muscle: potential role of myocyte enhancer factor 2 proteins in the activation of muscle-regeneration-associated genes by Akkila, W M, Chambers, R L, Ornatsky, O I, McDermott, J C

“…A subtractive hybridization and cloning strategy was used to identify genes that are up-regulated in regenerating compared with normal skeletal muscle. The…”
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Modulation of Human Aorta Smooth Muscle Cell Phenotype: A Study of Muscle-Specific Variants of Vinculin, Caldesmon, and Actin Expression by Glukhova, Marina A., Kabakov, Alexander E., Frid, Maria G., Ornatsky, Olga I., Belkin, Alexey M., Mukhin, Dmitry N., Orekhov, Alexander N., Koteliansky, Victor E., Smirnov, Vladimir N.

“…Vinculin- and caldesmon-immunoreactive forms and actin isoform patterns were studied in samples of normal and atherosclerotic human aorta. After removal of…”
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Dystrophin, vinculin, and aciculin in skeletal muscle subject to chronic use and disuse by REZVANI, M, ORNATSKY, O. I, CONNOR, M. K, EISENBERG, H. A, HOOD, D. A

“…Dystrophin is a subsarcolemmal protein that interacts with cytoskeletal actin and a glycoprotein complex in the plasma membrane. One potential function of…”
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