Search Results - "Orlow, I."

A risk prediction model for the development of subsequent primary melanoma in a population‐based cohort by Cust, A.E., Badcock, C., Smith, J., Thomas, N.E., Haydu, L.E., Armstrong, B.K., Law, M.H., Thompson, J.F., Kanetsky, P.A., Begg, C.B., Shi, Y., Kricker, A., Orlow, I., Sharma, A., Yoo, S., Leong, S.F., Berwick, M., Ollila, D.W., Lo, S.

“…Summary Background Guidelines for follow‐up of patients with melanoma are based on limited evidence. Objectives To guide skin surveillance, we developed a risk…”
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Association of IRF4 single‐nucleotide polymorphism rs12203592 with melanoma‐specific survival by Ward, S.V., Gibbs, D.C., Orlow, I., Thomas, N.E., Kanetsky, P.A., Luo, L., Cust, A.E., Anton‐Culver, H., Gruber, S.B., Gallagher, R.P., Rosso, S., Zanetti, R., Dwyer, T., Begg, C.B., Berwick, M.

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A pilot study of neuropsychological functions, APOE and amyloid imaging in patients with gliomas by Correa, D. D., Kryza-Lacombe, M., Zhou, X., Baser, R. E., Beattie, B. J., Beiene, Z., Humm, J., DeAngelis, L. M., Orlow, I., Weber, W., Osborne, J.

“…Brain tumor patients treated with radiotherapy (RT) often develop cognitive dysfunction, and recent studies suggest that the APOE ε-4 allele may influence…”
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Functional melanoma‐risk variant IRF4 rs12203592 associated with Breslow thickness: a pooled international study of primary melanomas by Gibbs, D.C., Ward, S.V., Orlow, I., Cadby, G., Kanetsky, P.A., Luo, L., Busam, K.J., Kricker, A., Armstrong, B.K., Cust, A.E., Anton‐Culver, H., Gallagher, R.P., Zanetti, R., Rosso, S., Sacchetto, L., Ollila, D.W., Begg, C.B., Berwick, M., Thomas, N.E.

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Genetic factors associated with naevus count and dermoscopic patterns: preliminary results from the Study of Nevi in Children (SONIC) by Orlow, I., Satagopan, J.M., Berwick, M., Enriquez, H.L., White, K.A.M., Cheung, K., Dusza, S.W., Oliveria, S.A., Marchetti, M.A., Scope, A., Marghoob, A.A., Halpern, A.C.

“…Summary Background Melanocytic naevi are an important risk factor for melanoma. Naevi with distinct dermoscopic patterns can differ in size, distribution and…”
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Deletion of the p16 and p15 genes in human bladder tumors by Orlow, I, Lacombe, L, Hannon, G J, Serrano, M, Pellicer, I, Dalbagni, G, Reuter, V E, Zhang, Z F, Beach, D, Cordon-Cardo, C

“…Two genes, p16 (also known as CDKN2, INK4A, or MTS1) and p15 (also described as INK4B or MTS2), are found in tandem at chromosome 9p21. These genes are…”
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Altered patterns of MDM2 and TP53 expression in human bladder cancer by Lianes, P, Orlow, I, Zhang, Z F, Oliva, M R, Sarkis, A S, Reuter, V E, Cordon-Cardo, C

“…The TP53 gene maps to the short arm of chromosome 17 (17p13.1) and encodes for a nuclear phosphoprotein of 53 kd (p53) involved in cell cycle control. The MDM2…”
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Alterations of INK4A and INK4B Genes in Adult Soft Tissue Sarcomas: Effect on Survival by Orlow, Irene, Drobnjak, Marija, Zhang, Zuo-Feng, Lewis, Jonathan, Woodruff, James M., Brennan, Murray F., Cordon-Cardo, Carlos

“…BACKGROUND: The INK4A and INK4B genes map to chromosome 9p21, with the INK4A gene encoding two protein products, p16 and p19ARF. Alterations of the INK4A and…”
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Evaluation of alterations in the tumor suppressor genes INK4A and INK4B in human bladder tumors by Orlow, I, Cordon-Cardo, C

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523 ANRIL inherited variants associated with primary melanoma TIL grade by Davari, D.R., Orlow, I., Kanetsky, P.A., Luo, L., Busam, K.J., Cust, A.E., Begg, C.B., Berwick, M., Thomas, N.E.

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526 Functional, inherited vitamin D-binding protein variants associated with mortality among melanoma patients by Gibbs, D.C., Thomas, N.E., Orlow, I., Kanetsky, P.A., Luo, L., Cust, A.E., Begg, C.B., Berwick, M., Ward, S.

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Validation of Denaturing High Performance Liquid Chromatography as a Rapid Detection Method for the Identification of Human INK4A Gene Mutations by Orlow, Irene, Roy, Pampa, Barz, Allison, Canchola, Rebecca, Song, Yan, Berwick, Marianne

“…The incidence of melanoma is increasing rapidly in western countries. Genetic predisposition in familial and in some sporadic melanomas has been associated…”
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Estimating the relative risk of developing melanoma in INK4A carriers by Berwick, M, Orlow, I, Mahabir, S, Myskowski, P, Coit, D, Brady, M S, Roy, P, Song, Y, Canchola, R, Barz, A, Halpern, A, Bolognia, J, Eng, S, Elahi, A, Begg, C B

“…Estimation of the relative risk of cancer due to rare germline mutations using population-based epidemiological techniques is challenging, since studies with…”
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163 Associations of phenotypic characteristics, MC1R variants, and prior amelanotic melanoma with incident amelanotic melanoma by Vernali, S., Kanetsky, P.A., Orlow, I., Luo, L., Berwick, M., Thomas, N.E.

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Previous lung diseases and lung cancer risk: a pooled analysis from the International Lung Cancer Consortium by Brenner, Darren R, Boffetta, Paolo, Duell, Eric J, Bickeböller, Heike, Rosenberger, Albert, McCormack, Valerie, Muscat, Joshua E, Yang, Ping, Wichmann, H-Erich, Brueske-Hohlfeld, Irene, Schwartz, Ann G, Cote, Michele L, Tjønneland, Anne, Friis, Søren, Le Marchand, Loic, Zhang, Zuo-Feng, Morgenstern, Hal, Szeszenia-Dabrowska, Neonila, Lissowska, Jolanta, Zaridze, David, Rudnai, Peter, Fabianova, Eleonora, Foretova, Lenka, Janout, Vladimir, Bencko, Vladimir, Schejbalova, Miriam, Brennan, Paul, Mates, Ioan N, Lazarus, Philip, Field, John K, Raji, Olaide, McLaughlin, John R, Liu, Geoffrey, Wiencke, John, Neri, Monica, Ugolini, Donatella, Andrew, Angeline S, Lan, Qing, Hu, Wei, Orlow, Irene, Park, Bernard J, Hung, Rayjean J

“…To clarify the role of previous lung diseases (chronic bronchitis, emphysema, pneumonia, and tuberculosis) in the development of lung cancer, the authors…”
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Association of IRF 4 single‐nucleotide polymorphism rs12203592 with melanoma‐specific survival by Ward, S.V., Gibbs, D.C., Orlow, I., Thomas, N.E., Kanetsky, P.A., Luo, L., Cust, A.E., Anton‐Culver, H., Gruber, S.B., Gallagher, R.P., Rosso, S., Zanetti, R., Dwyer, T., Begg, C.B., Berwick, M.

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Association of IRF4 SNP rs12203592 with melanoma-specific survival by Ward, S. V., Gibbs, D. C., Orlow, I., Thomas, N. E., Kanetsky, P. A., Luo, L., Cust, A. E., Anton-Culver, H., Gruber, S. B., Gallagher, R. P., Rosso, S., Zanetti, R., Dwyer, T., Begg, C. B., Berwick, M.

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Mutagen sensitivity as an indicator of soft tissue sarcoma risk by Berwick, M., Song, Y., Jordan, R., Brady, M. S., Orlow, I.

“…The etiology of soft tissue sarcoma is poorly understood. Exposure to environmental chemicals may play a role, but the data are not clear. We compared a group…”
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Functional melanoma‐risk variant IRF 4 rs12203592 associated with Breslow thickness: a pooled international study of primary melanomas by Gibbs, D.C., Ward, S.V., Orlow, I., Cadby, G., Kanetsky, P.A., Luo, L., Busam, K.J., Kricker, A., Armstrong, B.K., Cust, A.E., Anton‐Culver, H., Gallagher, R.P., Zanetti, R., Rosso, S., Sacchetto, L., Ollila, D.W., Begg, C.B., Berwick, M., Thomas, N.E.

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Cigarette smoking and chromosome 9 alterations in bladder cancer by Zhang, Z F, Shu, X M, Cordon-Cardo, C, Orlow, I, Lu, M L, Millon, T V, Cao, P Q, Connolly-Jenks, C, Dalbagni, G, Lianes, P, Lacombe, L, Reuter, V E, Scher, H

“…Epidemiological studies suggest that bladder cancer may be caused by carcinogens in tobacco and certain occupational exposures. Molecular studies have shown…”
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