Search Results - "Orlova, Nadezhda"

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  1. 1

    High-level expression of the monomeric SARS-CoV-2 S protein RBD 320-537 in stably transfected CHO cells by the EEF1A1-based plasmid vector by Sinegubova, Maria V, Orlova, Nadezhda A, Kovnir, Sergey V, Dayanova, Lutsia K, Vorobiev, Ivan I

    Published in PloS one (02-02-2021)
    “…The spike (S) protein is one of the three proteins forming the coronaviruses' viral envelope. The S protein of the Severe Acute Respiratory Syndrome…”
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    Journal Article
  2. 2

    High-level expression of biologically active human follicle stimulating hormone in the Chinese hamster ovary cell line by a pair of tricistronic and monocistronic vectors by Orlova, Nadezhda A, Kovnir, Sergey V, Khodak, Yulia A, Polzikov, Mikhail A, Nikitina, Victoria A, Skryabin, Konstantin G, Vorobiev, Ivan I

    Published in PloS one (05-07-2019)
    “…Recombinant human follicle stimulating hormone (FSH), produced in Chinese hamster ovary (CHO) cells, is widely used for treatment of fertility disorders and is…”
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    Journal Article
  3. 3

    Dimeric ACE2-FC Is Equivalent to Monomeric ACE2 in the Surrogate Virus Neutralization Test by Kolesov, Denis E., Gaiamova, Elizaveta A., Orlova, Nadezhda A., Vorobiev, Ivan I.

    Published in Biochemistry (Moscow) (01-09-2023)
    “…Angiotensin-converting enzyme 2 (ACE2) is the main cellular receptor for the dangerous sarbecoviruses SARS-CoV and SARS-CoV-2. Its recombinant extracellular…”
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    Journal Article
  4. 4

    Promoter from Chinese hamster elongation factor-1a gene and Epstein-Barr virus terminal repeats concatemer fragment maintain stable high-level expression of recombinant proteins by Sinegubova, Maria V, Orlova, Nadezhda A, Vorobiev, Ivan I

    Published in PeerJ (San Francisco, CA) (24-10-2023)
    “…Background The Chinese hamster ovary (CHO) cell line is the main host for the high-titer production of therapeutic and diagnostic proteins in the…”
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    Journal Article
  5. 5

    Russian agricultural innovations prospects in the context of global challenges: Agriculture 4.0 by Orlova, Nadezhda V., Nikolaev, Dmitry V.

    Published in Russian journal of economics (Moskva) (25-03-2022)
    “…For the last 10–15 years, Russia has become the key player in the world agricultural market. Increasing export volume up to $45 billion by 2025 is the…”
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    Journal Article
  6. 6

    Location and Orientation of the Genetic Toxin–Antitoxin Element hok/sok in the Plasmid Affect Expression of Pharmaceutically Significant Proteins in Bacterial Cells by Khodak, Yulia A., Shaifutdinov, Rolan R., Khasanov, Danila S., Orlova, Nadezhda A., Vorobiev, Ivan I.

    Published in Biochemistry (Moscow) (01-09-2023)
    “…Genetic toxin–antitoxin element hok / sok from the natural Escherichia coli R1 plasmid ensures segregational stability of plasmids. Bacterial cells that have…”
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    Journal Article
  7. 7

    Key trends of rural development in the world and their projection on Russia by Petukhova, Marina S., Rudoy, Evgeny V., Orlova, Nadezhda V.

    Published in Russian journal of economics (Moskva) (20-12-2023)
    “…This article is the first attempt by the authors to formulate key trends in the field of rural development. The main tool is a bibliometric analysis based on…”
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    Journal Article
  8. 8

    Geoecological situation in the region of the Erdenet mining and processing facility (Mongolia) by Jargalsaihan, Bolortuya, Orlova, Nadezhda Al, Suzdaleva, Antonina L.

    Published in E3S web of conferences (01-01-2023)
    “…The Erdenet mining and processing facility (Mongolia) develops a large copper-molybdenum deposit. The volume of waste in the tailings dump of the enterprise…”
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    Journal Article Conference Proceeding
  9. 9

    New Infestin-4 Mutants with Increased Selectivity against Factor XIIa by Kolyadko, Vladimir N, Lushchekina, Sofya V, Vuimo, Tatiana A, Surov, Stepan S, Ovsepyan, Ruzanna A, Korneeva, Vera A, Vorobiev, Ivan I, Orlova, Nadezhda A, Minakhin, Leonid, Kuznedelov, Konstantin, Severinov, Konstantin V, Ataullakhanov, Fazoil I, Panteleev, Mikhail A

    Published in PloS one (15-12-2015)
    “…Factor XIIa (fXIIa) is a serine protease that triggers the coagulation contact pathway and plays a role in thrombosis. Because it interferes with coagulation…”
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    Journal Article
  10. 10

    Drug Transport System Based on Phospholipid Nanoparticles: Production Technology and Characteristics by Tikhonova, Elena G, Sanzhakov, Maxim A, Tereshkina, Yulia A, Kostryukova, Lyubov V, Khudoklinova, Yulia Yu, Orlova, Nadezhda A, Bobrova, Daria V, Ipatova, Olga M

    Published in Pharmaceutics (01-11-2022)
    “…One of the current trends in modern pharmaceuticals is the supply of drugs by transport systems. The use of delivery systems allows to increase the therapeutic…”
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    Journal Article
  11. 11

    Purification Process of a Recombinant Human Follicle Stimulating Hormone Biosimilar (Primapur ® ) to Yield a Pharmaceutical Product with High Batch-to-Batch Consistency by Sinegubova, Maria, Vorobiev, Ivan, Klishin, Anatoly, Eremin, Dmitry, Orlova, Nadezhda, Orlova, Natalya, Polzikov, Mikhail

    Published in Pharmaceutics (01-01-2022)
    “…Recombinant human follicle stimulating hormone (r-hFSH) is widely used for infertility treatment and is subject to the development of biosimilars. There are…”
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    Journal Article
  12. 12

    Antigenic properties of the SARS-CoV-2 nucleoprotein are altered by the RNA admixture by Kolesov, Denis E, Sinegubova, Maria V, Safenkova, Irina V, Vorobiev, Ivan I, Orlova, Nadezhda A

    Published in PeerJ (San Francisco, CA) (07-01-2022)
    “…Determining the presence of antibodies to the SARS-CoV-2 antigens is the best way to identify infected people, regardless of the development of symptoms of…”
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    Journal Article
  13. 13

    Chlorin e6 Phospholipid Delivery System Featuring APN/CD13 Targeting Peptides: Cell Death Pathways, Cell Localization, In Vivo Biodistribution by Tereshkina, Yulia A, Kostryukova, Lyubov V, Tikhonova, Elena G, Khudoklinova, Yulia Yu, Orlova, Nadezhda A, Gisina, Alisa M, Morozevich, Galina E, Melnikov, Pavel A, Pokrovsky, Vadim S

    Published in Pharmaceutics (01-10-2022)
    “…We have previously designed a phospholipid delivery system for chlorin e6 to increase the efficacy of photodynamic therapy involving a second-generation…”
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    Journal Article
  14. 14

    Fast and Accurate Surrogate Virus Neutralization Test Based on Antibody-Mediated Blocking of the Interaction of ACE2 and SARS-CoV-2 Spike Protein RBD by Kolesov, Denis E, Sinegubova, Maria V, Dayanova, Lutsia K, Dolzhikova, Inna V, Vorobiev, Ivan I, Orlova, Nadezhda A

    Published in Diagnostics (Basel) (03-02-2022)
    “…The humoral response to the SARS-CoV-2 S protein determines the development of protective immunity against this infection. The standard neutralizing antibodies…”
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    Journal Article
  15. 15

    Stable high-level expression of factor VIII in Chinese hamster ovary cells in improved elongation factor-1 alpha-based system by Orlova, Nadezhda A, Kovnir, Sergey V, Gabibov, Alexandre G, Vorobiev, Ivan I

    Published in BMC biotechnology (24-03-2017)
    “…Recombinant factor VIII (FVIII), used for haemophilia A therapy, is one of the most challenging among the therapeutic proteins produced in heterologous…”
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    Journal Article
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    Semantic Structure and Dynamics of Precedential Situation of Bible Cradle by Orlova, Nadezhda

    “…The article deals with the issues connected with the Bible text as a precedential phenomenon in the Russian and European literature and culture. The Old…”
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    Journal Article
  19. 19

    Bible and Small Literary Genres: Russian Proverbs, Sayings, and Quotations by Orlova, Nadezhda Mikhailovna

    Published in Zhanry rechi (01-03-2020)
    “…The article considers genre aspects of set phrases of different type such as proverbs, sayings and quotations (aphorisms), going back to the Bible. The author…”
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    Journal Article
  20. 20

    Improved elongation factor-1 alpha-based vectors for stable high-level expression of heterologous proteins in Chinese hamster ovary cells by Orlova, Nadezhda A, Kovnir, Sergey V, Hodak, Julia A, Vorobiev, Ivan I, Gabibov, Alexandre G, Skryabin, Konstantin G

    Published in BMC biotechnology (14-06-2014)
    “…Establishing highly productive clonal cell lines with constant productivity over 2-3 months of continuous culture remains a tedious task requiring the…”
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    Journal Article