Search Results - "Orlova, Nadezhda"
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High-level expression of the monomeric SARS-CoV-2 S protein RBD 320-537 in stably transfected CHO cells by the EEF1A1-based plasmid vector
Published in PloS one (02-02-2021)“…The spike (S) protein is one of the three proteins forming the coronaviruses' viral envelope. The S protein of the Severe Acute Respiratory Syndrome…”
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High-level expression of biologically active human follicle stimulating hormone in the Chinese hamster ovary cell line by a pair of tricistronic and monocistronic vectors
Published in PloS one (05-07-2019)“…Recombinant human follicle stimulating hormone (FSH), produced in Chinese hamster ovary (CHO) cells, is widely used for treatment of fertility disorders and is…”
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3
Dimeric ACE2-FC Is Equivalent to Monomeric ACE2 in the Surrogate Virus Neutralization Test
Published in Biochemistry (Moscow) (01-09-2023)“…Angiotensin-converting enzyme 2 (ACE2) is the main cellular receptor for the dangerous sarbecoviruses SARS-CoV and SARS-CoV-2. Its recombinant extracellular…”
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4
Promoter from Chinese hamster elongation factor-1a gene and Epstein-Barr virus terminal repeats concatemer fragment maintain stable high-level expression of recombinant proteins
Published in PeerJ (San Francisco, CA) (24-10-2023)“…Background The Chinese hamster ovary (CHO) cell line is the main host for the high-titer production of therapeutic and diagnostic proteins in the…”
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5
Russian agricultural innovations prospects in the context of global challenges: Agriculture 4.0
Published in Russian journal of economics (Moskva) (25-03-2022)“…For the last 10–15 years, Russia has become the key player in the world agricultural market. Increasing export volume up to $45 billion by 2025 is the…”
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6
Location and Orientation of the Genetic Toxin–Antitoxin Element hok/sok in the Plasmid Affect Expression of Pharmaceutically Significant Proteins in Bacterial Cells
Published in Biochemistry (Moscow) (01-09-2023)“…Genetic toxin–antitoxin element hok / sok from the natural Escherichia coli R1 plasmid ensures segregational stability of plasmids. Bacterial cells that have…”
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7
Key trends of rural development in the world and their projection on Russia
Published in Russian journal of economics (Moskva) (20-12-2023)“…This article is the first attempt by the authors to formulate key trends in the field of rural development. The main tool is a bibliometric analysis based on…”
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8
Geoecological situation in the region of the Erdenet mining and processing facility (Mongolia)
Published in E3S web of conferences (01-01-2023)“…The Erdenet mining and processing facility (Mongolia) develops a large copper-molybdenum deposit. The volume of waste in the tailings dump of the enterprise…”
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Journal Article Conference Proceeding -
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New Infestin-4 Mutants with Increased Selectivity against Factor XIIa
Published in PloS one (15-12-2015)“…Factor XIIa (fXIIa) is a serine protease that triggers the coagulation contact pathway and plays a role in thrombosis. Because it interferes with coagulation…”
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10
Drug Transport System Based on Phospholipid Nanoparticles: Production Technology and Characteristics
Published in Pharmaceutics (01-11-2022)“…One of the current trends in modern pharmaceuticals is the supply of drugs by transport systems. The use of delivery systems allows to increase the therapeutic…”
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11
Purification Process of a Recombinant Human Follicle Stimulating Hormone Biosimilar (Primapur ® ) to Yield a Pharmaceutical Product with High Batch-to-Batch Consistency
Published in Pharmaceutics (01-01-2022)“…Recombinant human follicle stimulating hormone (r-hFSH) is widely used for infertility treatment and is subject to the development of biosimilars. There are…”
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12
Antigenic properties of the SARS-CoV-2 nucleoprotein are altered by the RNA admixture
Published in PeerJ (San Francisco, CA) (07-01-2022)“…Determining the presence of antibodies to the SARS-CoV-2 antigens is the best way to identify infected people, regardless of the development of symptoms of…”
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13
Chlorin e6 Phospholipid Delivery System Featuring APN/CD13 Targeting Peptides: Cell Death Pathways, Cell Localization, In Vivo Biodistribution
Published in Pharmaceutics (01-10-2022)“…We have previously designed a phospholipid delivery system for chlorin e6 to increase the efficacy of photodynamic therapy involving a second-generation…”
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14
Fast and Accurate Surrogate Virus Neutralization Test Based on Antibody-Mediated Blocking of the Interaction of ACE2 and SARS-CoV-2 Spike Protein RBD
Published in Diagnostics (Basel) (03-02-2022)“…The humoral response to the SARS-CoV-2 S protein determines the development of protective immunity against this infection. The standard neutralizing antibodies…”
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15
Stable high-level expression of factor VIII in Chinese hamster ovary cells in improved elongation factor-1 alpha-based system
Published in BMC biotechnology (24-03-2017)“…Recombinant factor VIII (FVIII), used for haemophilia A therapy, is one of the most challenging among the therapeutic proteins produced in heterologous…”
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16
The Use of Mesenchymal Stem Cells in the Complex Treatment of Kidney Tuberculosis (Experimental Study)
Published in Biomedicines (28-11-2022)“…In recent years, the application of mesenchymal stem cells (MSCs) has been recognized as a promising method for treatment of different diseases associated with…”
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Experimental bladder regeneration using a poly-l-lactide/silk fibroin scaffold seeded with nanoparticle-labeled allogenic bone marrow stromal cells
Published in International journal of nanomedicine (01-01-2016)“…In the present study, a poly-l-lactide/silk fibroin (PL-SF) bilayer scaffold seeded with allogenic bone marrow stromal cells (BMSCs) was investigated as a…”
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Semantic Structure and Dynamics of Precedential Situation of Bible Cradle
Published in Vestnik Volgogradskogo gosudarstvennogo universiteta. Serii͡a︡ 2, I͡A︡zykoznanie. (01-09-2015)“…The article deals with the issues connected with the Bible text as a precedential phenomenon in the Russian and European literature and culture. The Old…”
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Journal Article -
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Bible and Small Literary Genres: Russian Proverbs, Sayings, and Quotations
Published in Zhanry rechi (01-03-2020)“…The article considers genre aspects of set phrases of different type such as proverbs, sayings and quotations (aphorisms), going back to the Bible. The author…”
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20
Improved elongation factor-1 alpha-based vectors for stable high-level expression of heterologous proteins in Chinese hamster ovary cells
Published in BMC biotechnology (14-06-2014)“…Establishing highly productive clonal cell lines with constant productivity over 2-3 months of continuous culture remains a tedious task requiring the…”
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