Search Results - "Orlanski, Shari"

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  1. 1

    Detecting cell-of-origin and cancer-specific methylation features of cell-free DNA from Nanopore sequencing by Katsman, Efrat, Orlanski, Shari, Martignano, Filippo, Fox-Fisher, Ilana, Shemer, Ruth, Dor, Yuval, Zick, Aviad, Eden, Amir, Petrini, Iacopo, Conticello, Silvestro G, Berman, Benjamin P

    Published in Genome Biology (15-07-2022)
    “…The Oxford Nanopore (ONT) platform provides portable and rapid genome sequencing, and its ability to natively profile DNA methylation without complex sample…”
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    Journal Article
  2. 2

    Tissue-specific DNA demethylation is required for proper B-cell differentiation and function by Orlanski, Shari, Labi, Verena, Reizel, Yitzhak, Spiro, Adam, Lichtenstein, Michal, Levin-Klein, Rena, Koralov, Sergei B., Skversky, Yael, Rajewsky, Klaus, Cedar, Howard, Bergman, Yehudit

    “…There is ample evidence that somatic cell differentiation during development is accompanied by extensive DNA demethylation of specific sites that vary between…”
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    Journal Article
  3. 3

    Aberrant DNA methylation in ES cells by Ludwig, Guy, Nejman, Deborah, Hecht, Merav, Orlanski, Shari, Abu-Remaileh, Monther, Yanuka, Ofra, Sandler, Oded, Marx, Amichai, Roberts, Douglas, Benvenisty, Nissim, Bergman, Yehudit, Mendelsohn, Monica, Cedar, Howard

    Published in PloS one (22-05-2014)
    “…Both mouse and human embryonic stem cells can be differentiated in vitro to produce a variety of somatic cell types. Using a new developmental tracing…”
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    Journal Article
  4. 4

    Bright/Arid3A Acts as a Barrier to Somatic Cell Reprogramming through Direct Regulation of Oct4, Sox2, and Nanog by Popowski, Melissa, Templeton, Troy D., Lee, Bum-Kyu, Rhee, Catherine, Li, He, Miner, Cathrine, Dekker, Joseph D., Orlanski, Shari, Bergman, Yehudit, Iyer, Vishwanath R., Webb, Carol F., Tucker, Haley

    Published in Stem cell reports (14-01-2014)
    “…We show here that singular loss of the Bright/Arid3A transcription factor leads to reprograming of mouse embryonic fibroblasts (MEFs) and enhancement of…”
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  6. 6

    Using nucleosome levels, copy number alterations, and DNA methylation to profile disease state through liquid biopsy by Harrison, Sarah, Poplawski, Shane G., Orlanski, Shari, Wei, Melvin, Atteberry, Brandi, Berman, Benjamin P., Kelly, Terry

    Published in Journal of clinical oncology (01-06-2022)
    “…e15014 Background: Nucleosomes are the repeating unit of chromatin that contain important signals for proper genomic function and transcriptional activity…”
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  8. 8

    Sex of the cell dictates its response: differential gene expression and sensitivity to cell death inducing stress in male and female cells by Penaloza, Carlos, Estevez, Brian, Orlanski, Shari, Sikorska, Marianna, Walker, Roy, Smith, Catherine, Smith, Brandon, Lockshin, Richard A, Zakeri, Zahra

    Published in The FASEB journal (01-06-2009)
    “…Sexual dimorphisms are typically attributed to the hormonal differences arising once sex differentiation has occurred. However, in some sexually dimorphic…”
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  9. 9

    Epigenetic mechanism of FMR1 inactivation in Fragile X syndrome by Hecht, Merav, Tabib, Amalia, Kahan, Tamar, Orlanski, Shari, Gropp, Michal, Tabach, Yuval, Yanuka, Ofra, Benvenisty, Nissim, Keshet, Ilana, Cedar, Howard

    “…Fragile X syndrome is the most frequent cause of inherited intellectual disability. The primary molecular defect in this disease is the expansion of a CGG…”
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  10. 10

    Aberrant DNA Methylation in ES Cells: e96090 by Ludwig, Guy, Nejman, Deborah, Hecht, Merav, Orlanski, Shari, Abu-Remaileh, Monther, Yanuka, Ofra, Sandler, Oded, Marx, Amichai, Roberts, Douglas, Benvenisty, Nissim

    Published in PloS one (01-05-2014)
    “…Both mouse and human embryonic stem cells can be differentiated in vitro to produce a variety of somatic cell types. Using a new developmental tracing…”
    Get full text
    Journal Article