Search Results - "Orlando, Sonia"

Chlorambucil plus rituximab as front-line therapy for elderly and/or unfit chronic lymphocytic leukemia patients: correlation with biologically-based risk stratification by Laurenti, Luca, Innocenti, Idanna, Autore, Francesco, Ciolli, Stefania, Mauro, Francesca Romana, Mannina, Donato, Del Poeta, Giovanni, D'Arena, Giovanni, Massaia, Massimo, Coscia, Marta, Molica, Stefano, Pozzato, Gabriele, Efremov, Dimitar G, Vannata, Barbara, Marasca, Roberto, Galieni, Pietro, Cuneo, Antonio, Orlando, Sonia, Piciocchi, Alfonso, Boncompagni, Riccardo, Vincelli, Donatella, Liberati, Anna Marina, Russo, Filomena, Foá, Robin

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Fludarabine, cyclophosphamide and lenalidomide in patients with relapsed/refractory chronic lymphocytic leukemia. A multicenter phase I-II GIMEMA trial by Mauro, Francesca R., Carella, Angelo M., Molica, Stefano, Paoloni, Francesca, Liberati, Anna M., Zaja, Francesco, Belsito, Valeria, Cortellezzi, Agostino, Rizzi, Rita, Tosi, Patrizia, Spriano, Mauro, Ferretti, Antonietta, Nanni, Mauro, Marinelli, Marilisa, De Propris, Maria S., Orlando, Sonia M., Vignetti, Marco, Cuneo, Antonio, Guarini, Anna R., Foà, Robin

“…The activity and safety of a regimen combining lenalidomide with fludarabine and cyclophosphamide (FC) was investigated in patients with relapsed/refractory…”
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Clinico-biological features of 5202 patients with acute lymphoblastic leukemia enrolled in the Italian AIEOP and GIMEMA protocols and stratified in age cohorts by Chiaretti, Sabina, Vitale, Antonella, Cazzaniga, Gianni, Orlando, Sonia Maria, Silvestri, Daniela, Fazi, Paola, Valsecchi, Maria Grazia, Elia, Loredana, Testi, Anna Maria, Mancini, Francesca, Conter, Valentino, te Kronnie, Geertruy, Ferrara, Felicetto, Di Raimondo, Francesco, Tedeschi, Alessandra, Fioritoni, Giuseppe, Fabbiano, Francesco, Meloni, Giovanna, Specchia, Giorgina, Pizzolo, Giovanni, Mandelli, Franco, Guarini, Anna, Basso, Giuseppe, Biondi, Andrea, Foà, Robin

“…The outcome of children and adults with acute lymphoblastic leukemia is markedly different. Since there is limited information on the distribution of…”
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The Added Value of Multi-State Modelling in Acute Myeloid Leukemia: The Gimema AML1310 Study Post-Hoc Analysis by Piciocchi, Alfonso, Arena, Valentina, Messina, Monica, Orlando, Sonia Maria, Palmieri, Raffaele, Maurillo, Luca, Del Principe, Maria Ilaria, Fazi, Paola, Vignetti, Marco, Buccisano, Francesco, Venditti, Adriano

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Level of activity of neonatal intensive care units and mortality among very preterm infants: a nationwide study in Italy by Corchia, Carlo, Orlando, Sonia Maria

“…Objectives: To investigate the relationships between mortality of infants <32 weeks gestation and neonatal intensive care units' (NICUs) volume of activity,…”
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On the Children Side. Overview of 194 Outcomes from Gimema Registry of Conception/Pregnancy in Chronic Myeloid Leukemia (CML) by Abruzzese, Elisabetta, Chiara, Elena, Castagnetti, Fausto, Annunziata, Mario, Gambacorti-Passerini, Carlo, Luciano, Luigiana, Russo Rossi, Antonella, Iurlo, Alessandra, Capodanno, Isabella, Giai, Valentina, D'Adda, Mariella, Stagno, Fabio, Gozzini, Antonella, Tiribelli, Mario, Sorà, Federica, Galimberti, Sara, Bocchia, Monica, Beltrami, Germana, Fava, Carmen, Miggiano, Maria Cristina, Breccia, Massimo, Cerrano, Marco, Scortechini, Anna Rita, Mulas, Olga, Caracciolo, Clementina, Impera, Stefana, Fozza, Claudio, Malato, Alessandra, Mastrullo, Lucia, Salvucci, Marzia, Lunghi, Monia, Gherlinzoni, Filippo, De Fabritiis, Paolo, Fazi, Paola, Orlando, Sonia Maria, Piciocchi, Alfonso, Pane, Fabrizio

“…Pregnancy in patients with chronic myeloid leukemia (CML) is no longer precluded. The literature published to date has mainly evaluated the management of CML…”
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Next-Generation Sequencing (NGS) in Childhood Myeloproliferative Diseases (MPD) by Santopietro, Michelina, Palumbo, Giovanna, Moleti, Maria Luisa, Testi, Anna Maria, Cardarelli, Luisa, Monaco, Nicola, Malaspina, Francesco, Presicce, Camilla, Orlando, Sonia Maria, Pancrazzi, Alessandro, Pacilli, Annalisa, Rotunno, Giada, Vannucchi, Alessandro M., Foà, Robin, Giona, Fiorina

“…Driver mutations of JAK2, CALR and MPL are found in >90% of adults with BCR-ABL1-negative myeloproliferative neoplasms (MPN). In children, the presence of…”
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Thrombocythemia and polycythemia in patients younger than 20 years at diagnosis: clinical and biologic features, treatment, and long-term outcome by Giona, Fiorina, Teofili, Luciana, Moleti, Maria Luisa, Martini, Maurizio, Palumbo, Giovanna, Amendola, Angela, Mazzucconi, Maria Gabriella, Testi, Anna Maria, Pignoloni, Patrizia, Orlando, Sonia Maria, Capodimonti, Sara, Nanni, Mauro, Leone, Giuseppe, Larocca, Luigi Maria, Foà, Robin

“…Sixty-four patients < 20 years of age, investigated for a suspicion of Philadelphia-negative myeloproliferative disease (MPD), were retrospectively evaluated…”
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Long-Term Outcome in Children and Adolescents with Chronic Myeloid Leukemia in Chronic Phase Treated with High-Dose Imatinib— the Italian Experience by Giona, Fiorina, Santopietro, Michelina, Menna, Giuseppe, Micalizzi, Concetta, Putti, Maria Caterina, Santoro, Nicola, Ziino, Ottavio, Mura, Rosamaria, Ladogana, Saverio, Iaria, Grazia, Sau, Antonella, Burnelli, Roberta, Vacca, Nadia, Nardi, Margherita, Consarino, Caterina, Miulli, Eleonora, Moleti, Maria Luisa, Petruzziello, Fara, Orlando, Sonia Maria, Biondi, Andrea, Locatelli, Franco, Saglio, Giuseppe, Foa, Robin

“…The availability of imatinib (IM) and thereafter of second-generation tyrosine kinase inhibitors (TKI2) has extended therapeutic options for childhood chronic…”
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Treatment of Acute Promyelocytic Leukemia by Miura, Yuji, Suyama, Koichi, Takano, Toshimi, Lo-Coco, Francesco, Orlando, Sonia M, Platzbecker, Uwe

“…To the Editor: Lo-Coco et al. (July 11 issue) 1 report that a combination of all- trans retinoic acid (ATRA) and arsenic trioxide as an induction and…”
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Chlorambucil PLUS Rituximab As FRONT-LINE Therapy for Elderly and/or Unfit CLL Patients. LONG-TERM Follow-up and Correlation with Biologic-Based Risk Stratification by Laurenti, Luca, Innocenti, Idanna, Autore, Francesco, Pasquale, Raffaella, Vannata, Barbara, Ciolli, Stefania, Mauro, Francesca Romana, Mannina, Donato, Del Poeta, Giovanni, D'Arena, Giovanni, Massaia, Massimo, Coscia, Marta, Molica, Stefano, Pozzato, Gabriele, Efremov, Dimitar G, Marasca, Roberto, Galieni, Piero, Cuneo, Antonio, Orlando, Sonia, Piciocchi, Alfonso, Boncompagni, Riccardo, Vincelli, Donatella Iolanda, Liberati, Anna Marina, Russo, Filomena, Foa, Robin

“…▪ Introduction. Elderly patients with chronic lymphocytic leukemia (CLL) and younger patients with comorbidities are often treated with chlorambucil (Chl),…”
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Can chronic myeloid leukaemia in children and adolescents be successfully treated without haematopoietic stem cell transplant? A single centre experience by Giona, Fiorina, Moleti, Maria L., De Benedittis, Daniela, Santopietro, Michelina, Nanni, Mauro, Testi, Anna M., Orlando, Sonia, Iori, Anna P., Piciocchi, Alfonso, Gottardi, Enrico, Barberi, Walter, Diverio, Daniela, Saglio, Giuseppe, Foà, Robin

“…Summary We analysed the long‐term outcome of 35 children and adolescents (<20 years at diagnosis) with chronic myeloid leukaemia (CML) in chronic phase: 20…”
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BIRC3 disruption and Copy Number Aberrations in Chronic Lymphocytic Leukemia (CLL) Patients with 11q Deletion by Del Giudice, Ilaria, Bonina, Silvia, Marinelli, Marilisa, Cafforio, Luciana, Raponi, Sara, Boldrini, Eloise, Bonafede, Alexia, Tavolaro, Simona, Ilari, Caterina, Messina, Monica, Chiaretti, Sabina, Mauro, Francesca Romana, Piciocchi, Alfonso, Orlando, Sonia Maria, Rigolin, Gian Matteo, Cuneo, Antonio, Rossi, Davide, Gaidano, Gianluca, Guarini, Anna, Foá, Robin

“…Introduction. Chronic lymphocytic leukemia (CLL) with 11q deletion has been associated to a poor prognosis, but the clinical course of patients carrying this…”
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Improved Outcome with ATRA-Arsenic Trioxide Compared to ATRA-Chemotherapy in Non-High Risk Acute Promyelocytic Leukemia – Updated Results of the Italian-German APL0406 Trial on the Extended Final Series by Platzbecker, Uwe, Avvisati, Giuseppe, Ehninger, Gerhard, Cicconi, Laura, Thiede, Christian, Ferrara, Felicetto, Orlando, Sonia Maria, Vignetti, Marco, Specchia, Giorgina, Sborgia, Marco, Di Bona, Eros, Breccia, Massimo, Cerqui, Elisa, Döhner, Konstanze, Fiedler, Walter, von Lilienfeld-Toal, Marie, Hertenstein, Bernd, Salih, Helmut R., Wattad, Mohammed, Lübbert, Michael, Brandts, Christian H., Hänel, Mathias, Schmitz, Norbert, Link, Hartmut, Divona, Mariadomenica, Frairia, Chiara, Pogliani, Enrico Maria, Fozza, Claudio, D’Arco, Alfonso Maria, Di Renzo, Nicola, Cortelezzi, Agostino, Fabbiano, Francesco, Fazi, Paola, Kullmer, Johannes, Aulitzky, Walter E., Krause, Stefan W., Salwender, Hans, Schäfer-Eckart, Kerstin, Radsak, Markus P., Ganser, Arnold, Döhner, Hartmut, Amadori, Sergio, Mandelli, Franco, Schlenk, Richard F., Lo-Coco, Francesco

“…▪ Background: We recently showed that the combination of ATRA and arsenic trioxide (ATO) is at least not inferior and possibly superior to standard ATRA and…”
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Retinoic Acid and Arsenic Trioxide for Acute Promyelocytic Leukemia by Lo-Coco, Francesco, Avvisati, Giuseppe, Vignetti, Marco, Thiede, Christian, Orlando, Sonia Maria, Iacobelli, Simona, Ferrara, Felicetto, Fazi, Paola, Cicconi, Laura, Di Bona, Eros, Specchia, Giorgina, Sica, Simona, Divona, Mariadomenica, Levis, Alessandro, Fiedler, Walter, Cerqui, Elisa, Breccia, Massimo, Fioritoni, Giuseppe, Salih, Helmut R, Cazzola, Mario, Melillo, Lorella, Carella, Angelo M, Brandts, Christian H, Morra, Enrica, von Lilienfeld-Toal, Marie, Hertenstein, Bernd, Wattad, Mohammed, Lübbert, Michael, Hänel, Matthias, Schmitz, Norbert, Link, Hartmut, Kropp, Maria Grazia, Rambaldi, Alessandro, La Nasa, Giorgio, Luppi, Mario, Ciceri, Fabio, Finizio, Olimpia, Venditti, Adriano, Fabbiano, Francesco, Döhner, Konstanze, Sauer, Michaela, Ganser, Arnold, Amadori, Sergio, Mandelli, Franco, Döhner, Hartmut, Ehninger, Gerhard, Schlenk, Richard F, Platzbecker, Uwe

“…All- trans retinoic acid (ATRA) plus arsenic trioxide was found to be noninferior to ATRA plus chemotherapy, and less toxic, in the treatment of acute…”
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Fludarabine, Cyclophosphamide and Lenalidomide (FCL) for Previously Treated Patients with Chronic Lymphocytic Leukemia (CLL): Results of the Dose-Finding Phase of the GIMEMA LLC606 Study by Mauro, Francesca Romana, Armiento, Daniele, Orlando, Sonia, Giudice, Ilaria Del, De Propriis, Maria Stefania, Nanni, Mauro, Marinelli, Marilisa, Matteo, Molica, Fazi, Paola, Paoloni, Francesca, Antonietta, Graziosi, Collada, Laura, Guarini, Anna, Foà, Robin

“…Abstract 1377 Targeting the CLL microenvironment with immunomodulatory agents like lenalidomide results in antileukemic activity. Addition of lenalidomide to…”
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ATRA and Arsenic Trioxide (ATO) Versus ATRA and Idarubicin (AIDA) for Newly Diagnosed, Non High-Risk Acute Promyelocytic Leukemia (APL): Results of the Phase III, Prospective, Randomized, Intergroup APL0406 Study by the Italian-German Cooperative Groups Gimema-SAL-AMLSG by Lo-Coco, Francesco, Avvisati, Giuseppe, Orlando, Sonia Maria, Ferrara, Felicetto, Vignetti, Marco, Fazi, Paola, Di Bona, Eros, Specchia, Giorgina, Sica, Simona, Divona, Mariadomenica, Levis, Alessandro, Fiedler, Walter, Cerqui, Elisa, Breccia, Massimo, Fioritoni, Giuseppe, Salih, Helmut R, Brandts, Christian H., Morra, Enrica, von Lilienfeld-Toal, Marie, Hertenstein, Bernd, Wattad, Mohammed, Lubbert, Michael, Hänel, Matthias, Schmitz, Norbert, Link, Hartmut, Kropp, Maria Grazia, Rambaldi, Alessandro, La Nasa, Giorgio, Luppi, Mario, Ciceri, Fabio, Sauer, Michaela, Dohner, Hartmut, Ganser, Arnold, Mandelli, Franco, Ehninger, Gerhard, Amadori, Sergio, Thiede, Christian, Schlenk, Richard F, Platzbecker, Uwe

“…Abstract 6 Simultaneous ATRA and chemotherapy (CHT) is the current gold standard for newly diagnosed APL resulting in ∼80% cure rates, while arsenic trioxide…”
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Clinical and Biological Features, Treatment and Long-Term Outcome of 65 Children with Ph- Myeloprolipherative Disorders (MPD) by Giona, Fiorina, Teofili, Luciana, Palumbo, Giovanna, Moleti, Maria Luisa, Rea, Massimiliano, Orlando, Sonia Maria, Nunes, Vittorio, Testi, Anna Maria, Cecinati, Valerio, Capodimonte, Sara, Nanni, Mauro, Larocca, Luigi Maria, Foà, Robin

“…Abstract 1889 Poster Board I-912 MPD rarely occur in children and published data of pediatric patients (pts) are limited. In adults, current diagnostic…”
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Acute Erythroid Leukemia: A Distinctive Subtype of AML? Outcome and Prognostic Factors in Comparison with Non-M6 AML. The Gimema Experience by Pulsoni, Alessandro, Breccia, Massimo, Orlando, Sonia Maria, Bernardi, Massimo, Borgia, Marco, Camera, Andrea, Cantore, Nicola, Raimondo, Francesco Di, Fazi, Paola, Ferrara, Felicetto, Bosi, Alberto, De Angelis, Federico, Mancini, Marco, Marmont, Filippo, Melillo, Lorella, Meloni, Giovanna, Mirto, Salvatore, Specchia, Giorgina, Venditti, Adriano, Amadori, Sergio, Leone, Giuseppe, Foa, Robin, Pagano, Livio

“…Abstract 1019 Poster Board I-41 Erythroleukemia is characterized by a peculiar marrow feature: a proliferation of erythroblasts greater than 50% and of…”
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