Search Results - "Orji, O. U."

Molecular docking as a tool for the discovery of molecular targets of nutraceuticals in diseases management by Agu, P. C., Afiukwa, C. A., Orji, O. U., Ezeh, E. M., Ofoke, I. H., Ogbu, C. O., Ugwuja, E. I., Aja, P. M.

“…Molecular docking is a computational technique that predicts the binding affinity of ligands to receptor proteins. Although it has potential uses in…”
Get full text

Cucumeropsis mannii seed oil (CMSO) restores testicular mitochondrial dysfunctions by modulating the activities of dysregulated testicular mitochondrial enzymes in male albino rats exposed to bisphenol A by Ogwoni, H. A., Aja, P. M., Eze, Ejike Daniel, Agu, P. C., Moyosore, Afodun Adam, Ale, B. A., Ekpono, E. U., Awoke, J. N., Ogbu, Patience N., Ukachi, O. U., Orji, O. U., Nweke, P. C., Egwu, C. O., Ekpono, E. U., Ewa, G. O., Igwenyi, I. O., Alum, E. U., Chukwu, D. C., Aja, Lucy, Ani, G. O., Offor, C. E., Yakubu, O. E., Maduagwuna, E., Akobi, J. B., Noreen, Sana, Awuchi, Chinaza Godswill

“…Bisphenol A, a traditional endocrine disruptor, has been implicated in male infertility. This study investigated the effect of Cucumeropsis mannii seed oil…”
Get full text

Hesperidin abrogates bisphenol A endocrine disruption through binding with fibroblast growth factor 21 (FGF-21), α-amylase and α-glucosidase: an in silico molecular study by Aja, P.M., Awoke, J.N., Agu, P.C., Adegboyega, A.E., Ezeh, E.M., Igwenyi, I.O., Orji, O.U., Ani, O.G., Ale, B.A., Ibiam, U.A.

“…Abstract Background Fibroblast growth factor 21 (FGF-21), alpha-amylase, and alpha-glucosidase are key proteins implicated in metabolic dysregulations…”
Get full text

Assessment of Levels and Health Risks of Trace Metals in Soils and Food Crops Cultivated on Farmlands Near Enyigba Mining Sites, Ebonyi State, Nigeria by Orji, O U, Ibiam, U A, Awoke, J N, Obasi, O D, Uraku, A J, Alum, E U, Eze, A G

“…In most developing countries, mining is one of the major sources of toxic heavy metals, some of which are a major health concern to the surrounding populace…”
Get more information

Toxic metals bioremediation potentials of Paenibacillus sp. strain SEM1 and Morganella sp. strain WEM7 isolated from Enyigba Pb-Zn mining site, Ebonyi State Nigeria by Orji, O. U., Awoke, J. N., Aloke, C., Obasi, O. D., Oke, B., Njoku, M., Ezeani, N. N.

“…Heavy metal contamination is a serious environmental and ecological problem currently facing many countries. Discovering a novel biological means of…”
Get full text

Anti-arthritic potential of ethanol and aqueous extracts of stem bark of Cleistopholis patens on complete Freund's adjuvant-induced rheumatoid arthritis in rats by Aloke, C., Ibiam, U.A., Orji, O.U., Ugwuja, E.I., Ezeani, N.N., Aja, P.M., Obasi, N.A.

“…Traditional medicine intervention has been used in rheumatoid arthritis (RA) treatment due to limitations of conventional drugs. This study aimed at evaluating…”
Get full text

Halotolerant and metalotolerant bacteria strains with heavy metals biorestoration possibilities isolated from Uburu Salt Lake, Southeastern, Nigeria by Orji, O.U., Awoke, J.N., Aja, P.M., Aloke, C., Obasi, O.D., Alum, E.U., Udu-Ibiam, O.E., Oka, G.O.

“…Environmental contaminations by heavy metals are currently an increasing public health concern globally. One key challenge of these toxic metals is the…”
Get full text

Hesperidin ameliorates hepatic dysfunction and dyslipidemia in male Wistar rats exposed to cadmium chloride by Aja, P.M., Ekpono, E.U., Awoke, J.N., Famurewa, A.C., Izekwe, F.I., Okoro, E.J., Okorie, C.F., Orji, C.L., Nwite, F., Ale, B.A., Aku, A.F., Igwenyi, I.O., Nwali, B.U., Orji, O.U., Ani, O.G., Ozoemena, C.R., Anizoba, G.C.

“…[Display omitted] •Exposure of rats to CdCl2 led to hepatic dysfunction and dyslipidemia.•CdCl2 caused abnormal rapid weight reduction in rats.•Hesperidin…”
Get full text

Cucumeropsis mannii seed oil (CMSO) attenuates alterations in testicular biochemistry and histology against Bisphenol a-induced toxicity in male Wister albino rats by Agu, P.C., Aja, P.M., Ekpono Ugbala, Ezebuilo, Ogwoni, H.A., Ezeh, E.M., Oscar-Amobi, P.C., Asuk Atamgba, Agbor, Ani, O.G., Awoke, J.N., Nwite, F.E., Ukachi, O.U., Orji, O.U., Nweke, P.C., Ekpono Ugbala, Ejike, Ewa, G.O., Igwenyi, I.O., Egwu, C.O., Alum, E.U., Chukwu, D.C., Famurewa, A.C.

“…Male reproductive health has deteriorated in recent years as a result of industrialization, which has led to the use of desirable chemicals, like Bisphenol A…”
Get full text

Ethanol leaf extract of Psychotria microphylla rich in quercetin restores heavy metal induced redox imbalance in rats by Orji, O.U., Awoke, J.N., Harbor, C., Igwenyi, I.O., Obasi, O.D., Ezeani, N.N., Aloke, C.

“…Psychotria microphylla is a plant found in Africa and many parts of the world where the leaves are locally used in folk medicine for the treatment of toxicity…”
Get full text

Hesperidin abrogates bisphenol A endocrine disruption through binding with fibroblast growth factor 21 , [alpha]-amylase and [alpha]-glucosidase: an in silico molecular study by Aja, P. M, Awoke, J. N, Agu, P. C, Adegboyega, A. E, Ezeh, E. M, Igwenyi, I. O, Orji, O. U

“…Background Fibroblast growth factor 21 (FGF-21), alpha-amylase, and alpha-glucosidase are key proteins implicated in metabolic dysregulations. Bisphenol A…”
Get full text

Ethanol leaf extract of Ruspolia hypocrateriformis abrogated hepatic redox imbalance and oxidative damage induced by heavy metal toxicity in rats by Awoke, J.N., Orji, O.U., Aja, P.M., Ezeani, N.N., Aloke, C., Obasi, O.D.

“…•Heavy metal exposure causes hepatic redox imbalance and oxidative damage in rats.•Leaf extract of Ruspolia hypocrateriformis is highly rich in phenolic…”
Get full text

Potentials of Afzelia Africana Vegetable Oil in Biodiesel Production by Igwenyi, I.O., Offor, C.E., Aja, P.M., Aloh, G.S., Orji, O.U., Afiukwa, C.A.

Get full text