Search Results - "Ori, M"
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ReMAPping the microtubule landscape: How phosphorylation dictates the activities of microtubule‐associated proteins
Published in Developmental dynamics (01-01-2018)“…Classical microtubule‐associated proteins (MAPs) were originally identified based on their co‐purification with microtubules assembled from mammalian brain…”
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Golgi Outposts Shape Dendrite Morphology by Functioning as Sites of Acentrosomal Microtubule Nucleation in Neurons
Published in Neuron (Cambridge, Mass.) (06-12-2012)“…Microtubule nucleation is essential for proper establishment and maintenance of axons and dendrites. Centrosomes, the primary site of nucleation in most cells,…”
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3
Psychedelics Promote Structural and Functional Neural Plasticity
Published in Cell reports (Cambridge) (12-06-2018)“…Atrophy of neurons in the prefrontal cortex (PFC) plays a key role in the pathophysiology of depression and related disorders. The ability to promote…”
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Competition between microtubule-associated proteins directs motor transport
Published in Nature communications (16-04-2018)“…Within cells, motor and non-motor microtubule-associated proteins (MAPs) simultaneously converge on the microtubule. How the binding activities of non-motor…”
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Tau oligomerization on microtubules in health and disease
Published in Cytoskeleton (Hoboken, N.J.) (01-01-2024)Get full text
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A Combinatorial MAP Code Dictates Polarized Microtubule Transport
Published in Developmental cell (06-04-2020)“…Many eukaryotic cells distribute their intracellular components asymmetrically through regulated active transport driven by molecular motors along microtubule…”
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Synergistic autoinhibition and activation mechanisms control kinesin-1 motor activity
Published in Cell reports (Cambridge) (31-05-2022)“…Kinesin-1 activity is regulated by autoinhibition. Intramolecular interactions within the kinesin heavy chain (KHC) are proposed to be one facet of motor…”
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Effects of fitspiration on believability and intention to exercise
Published in Frontiers in psychology (20-02-2023)“…Although Fitspiration is purportedly intended to motivate people to be fit and healthy, a body of research has demonstrated negative effects of these media in…”
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A cytoplasmic dynein tail mutation impairs motor processivity
Published in Nature cell biology (01-12-2010)“…Mutations in the tail of the cytoplasmic dynein molecule have been reported to cause neurodegenerative disease in mice. The mutant mouse strain Legs at odd…”
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Autoregulatory control of microtubule binding in doublecortin-like kinase 1
Published in eLife (26-07-2021)“…The microtubule-associated protein, doublecortin-like kinase 1 (DCLK1), is highly expressed in a range of cancers and is a prominent therapeutic target for…”
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High-resolution imaging reveals indirect coordination of opposite motors and a role for LIS1 in high-load axonal transport
Published in The Journal of cell biology (17-10-2011)“…The specific physiological roles of dynein regulatory factors remain poorly understood as a result of their functional complexity and the interdependence of…”
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The short-term effects of a mass reach physical activity campaign: an evaluation using hierarchy of effects model and intention profiles
Published in BMC public health (27-11-2018)“…Mass reach physical activity campaigns are designed to deliver physical-activity related messages to a large population across different media including print,…”
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A Systematic Review of Community-wide Media Physical Activity Campaigns: An Update From 2010
Published in Journal of physical activity & health (01-07-2017)“…Mass media campaign is an integral tool to influence physical activity participant behaviors. The purpose of the systematic review was to identify the…”
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14
Diagnostic Capability of Comprehensive Handheld vs Transthoracic Echocardiography
Published in Mayo Clinic proceedings (01-06-2014)“…Abstract Objective To assess the diagnostic capability of handheld echocardiography (HHE) compared with transthoracic echocardiography (TTE) performed and…”
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A general implementation of TMLE for longitudinal data applied to causal inference in survival analysis
Published in The international journal of biostatistics (18-09-2012)“…In many randomized controlled trials the outcome of interest is a time to event, and one measures on each subject baseline covariates and time-dependent…”
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Ectopic Hoxa2 induction after neural crest migration results in homeosis of jaw elements in Xenopus
Published in Development (Cambridge) (15-12-2000)“…Hox genes are required to pattern neural crest (NC) derived craniofacial and visceral skeletal structures. However, the temporal requirement of Hox patterning…”
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Leveraging Professional Sports Teams to Encourage Healthy Behavior: A Review of 4 Years of Calgary Flames Health Training Camp Events
Published in Frontiers in public health (20-11-2020)“…Professional sporting teams may be well-positioned to act as promoters of health behaviors given their fixture within a community, and association with…”
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Collaborative targeted maximum likelihood for time to event data
Published in The international journal of biostatistics (01-01-2010)“…Current methods used to analyze time to event data either rely on highly parametric assumptions which result in biased estimates of parameters which are purely…”
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Serotonin signaling contribution to an evolutionary success: the jaw joint of vertebrates
Published in European zoological journal (2017)“…Serotonin (5-HT) is an ancient molecule that appeared very early during evolution, and it is present in different phyla. The 5-HT signaling system includes…”
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RHAMM mRNA expression in proliferating and migrating cells of the developing central nervous system
Published in Gene Expression Patterns (01-02-2010)“…Extracellular matrix components can influence cell behaviour by modulating a wide variety of events. In particular, the glycosaminoglycan hyaluronan is…”
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