Search Results - "Orhant, Magali"

Recycling of the actin monomer pool limits the lifetime of network turnover by Colin, Alexandra, Kotila, Tommi, Guérin, Christophe, Orhant‐Prioux, Magali, Vianay, Benoit, Mogilner, Alex, Lappalainen, Pekka, Théry, Manuel, Blanchoin, Laurent

“…Intracellular organization is largely mediated by actin turnover. Cellular actin networks continuously assemble and disassemble, while maintaining their…”
Get full text

Actin network architecture can ensure robust centering or sensitive decentering of the centrosome by Yamamoto, Shohei, Gaillard, Jérémie, Vianay, Benoit, Guerin, Christophe, Orhant‐Prioux, Magali, Blanchoin, Laurent, Théry, Manuel

“…The orientation of cell polarity depends on the position of the centrosome, the main microtubule‐organizing center (MTOC). Microtubules (MTs) transmit pushing…”
Get full text

Structural and biochemical evidence for the emergence of a calcium-regulated actin cytoskeleton prior to eukaryogenesis by Akıl, Caner, Tran, Linh T., Orhant-Prioux, Magali, Baskaran, Yohendran, Senju, Yosuke, Takeda, Shuichi, Chotchuang, Phatcharin, Muengsaen, Duangkamon, Schulte, Albert, Manser, Edward, Blanchoin, Laurent, Robinson, Robert C.

“…Charting the emergence of eukaryotic traits is important for understanding the characteristics of organisms that contributed to eukaryogenesis. Asgard archaea…”
Get full text

New Automatized Method of 3D Multiculture Viability Analysis Based on Confocal Imagery: Application to Islets and Mesenchymal Stem Cells Co-Encapsulation by Chabert, Clovis, Laporte, Camille, Fertin, Arnold, Tubbs, Emily, Cottet-Rousselle, Cécile, Rivera, Florence, Orhant-Prioux, Magali, Moisan, Anaick, Fontaine, Eric, Benhamou, Pierre-Yves, Lablanche, Sandrine

“…Co-encapsulation of pancreatic islets with mesenchymal stem cells in a three-dimensional biomaterial's structure is a promising technique to improve…”
Get full text

Tyrosine phosphorylation of transcriptional coactivator WW‐domain binding protein 2 regulates estrogen receptor α function in breast cancer via the Wnt pathway by Lim, Shen Kiat, Orhant‐Prioux, Magali, Toy, Weiyi, Tan, Kah Yap, Lim, Yoon Pin

“…ABSTRACT WW‐binding protein 2 (WBP2) has been demonstrated in different studies to be a tyrosine kinase substrate, to activate estrogen receptor a…”
Get full text

Abstract 4971: WBP2: A novel phospho-oncoprotein in estrogen receptor-positive breast cancer by Lim, Shen Kiat, Prioux, Magali Orhant, Tan, Kah Yap, Lim, Yoon Pin

“…WBP2 (WW-domain Binding Protein 2) was first implicated in breast cancer through our previous phosphoproteomics screen on the MCF10AT xenograft-derived…”
Get full text

Insights into the evolution of regulated actin dynamics via characterization of primitive gelsolin/cofilin proteins from Asgard archaea by Akıl, Caner, Tran, Linh T., Orhant-Prioux, Magali, Baskaran, Yohendran, Manser, Edward, Blanchoin, Laurent, Robinson, Robert C.

“…Asgard archaea genomes contain potential eukaryotic-like genes that provide intriguing insight for the evolution of eukaryotes. The eukaryotic actin…”
Get full text

Microtubules under mechanical pressure can breach dense actin networks by Gélin, Matthieu, Schaeffer, Alexandre, Gaillard, Jérémie, Guérin, Christophe, Vianay, Benoit, Orhant-Prioux, Magali, Braun, Marcus, Leterrier, Christophe, Blanchoin, Laurent, Théry, Manuel

“…The crosstalk between the actin network and microtubules is essential for cell polarity. It orchestrates microtubule organization within the cell, driven by…”
Get full text

Friction patterns guide actin network contraction by Colin, Alexandra, Orhant-Prioux, Magali, Guérin, Christophe, Savinov, Mariya, Cao, Wenxiang, Vianay, Benoit, Scarfone, Ilaria, Roux, Aurélien, De La Cruz, Enrique M, Mogilner, Alex, Théry, Manuel, Blanchoin, Laurent

“…The shape of cells is the outcome of the balance of inner forces produced by the actomyosin network and the resistive forces produced by cell adhesion to their…”
Get full text

Differential expression of genes related to HFE and iron status in mouse duodenal epithelium by Abgueguen, Emmanuelle, Toutain, Bertrand, Bédrine, Hélène, Chicault, Céline, Orhant, Magali, Aubry, Marc, Monnier, Annabelle, Mottier, Stéphanie, Jouan, Hélène, Bahram, Seiamak, Mosser, Jean, Fergelot, Patricia

“…Iron absorption, distribution, use, and storage are thought to be tightly regulated since altered iron stores may lead to cellular damage and disease. HFE, the…”
Get full text

Iron Overload in Mice Expressing HFE Exclusively in the Intestinal Villi Provides Evidence That HFE Regulates a Functional Cross-Talk between Crypt and Villi Enterocytes by Fergelot, Patricia, Ropert-Bouchet, Martine, Abgueguen, Emmanuelle, Orhant, Magali, Radosavljevic, Mirjana, Grimber, Gisèle, Jouan, Hélène, Le Gall, Jean-Yves, Mosser, Jean, Gilfillan, Susan, Bahram, Seiamak

“…ABSTRACT Hereditary hemochromatosis (HH), a common autosomal recessive disorder due to a mutation in HFE, which encodes an atypical MHC class I glycoprotein,…”
Get full text

Over-expression of wild-type and mutant HFE in a human melanocytic cell line reveals an intracellular bridge between MHC class I pathway and transferrin iron uptake by Fergelot, Patricia, Orhant, Magali, Thénié, Agnès, Loyer, Pascal, Ropert-Bouchet, Martine, Lohyer, Stéphanie, Le Gall, Jean-Yves, Mosser, Jean

“…Hereditary hemochromatosis (HH) is a frequent recessive disorder of iron metabolism characterised by systemic iron overload. In Northern Europe, more than 90%…”
Get full text

The HFE Gene Undergoes Alternate Splicing Processes by Thénié, Agnès, Orhant, Magali, Gicquel, Isabelle, Fergelot, Patricia, Le Gall, Jean-Yves, David, Véronique, Mosser, Jean

“…ABSTRACT The MHC class I-related HFE gene appears to be involved in iron metabolism, but its pathogenic mechanism in hemochromatosis remains unknown…”
Get full text