Search Results - "Orhan, Ilkay E"

Natural Products and Extracts as Xantine Oxidase Inhibitors - A Hope for Gout Disease? by Orhan, Ilkay E, Deniz, Fatma S S

“…Xanthine oxidase (EC 1.17.3.2) (XO) is one of the main enzymatic sources that create reactive oxygen species (ROS) in the living system. It is a dehydrogenase…”
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Deciphering Neuroprotective Effect of Rosmarinus officinalis L. (syn. Salvia rosmarinus Spenn.) through Preclinical and Clinical Studies by Oresanya, Ibukun O, Orhan, Ilkay E

“…L. (RO, rosemary) is a well-known medicinal, aromatic, and culinary herb with traditional use in European folk medicine against memory deficits and…”
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Dual Monoamine Oxidase and Cholinesterase Inhibitors with Different Heterocyclic Scaffolds by Gulcan, Hayrettin O, Orhan, Ilkay E

“…For the last two decades, there has been research interest on the design of molecules possessing dual inhibitory potential on cholinesterase and monoamine…”
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Norditerpenoids with Selective Anti-Cholinesterase Activity from the Roots of Perovskia atriplicifolia Benth by Ślusarczyk, Sylwester, Senol Deniz, F Sezer, Abel, Renata, Pecio, Łukasz, Pérez-Sánchez, Horacio, Cerón-Carrasco, José P, den-Haan, Helena, Banerjee, Priyanka, Preissner, Robert, Krzyżak, Edward, Oleszek, Wiesław, E Orhan, Ilkay, Matkowski, Adam

“…Inhibition of cholinesterases remains one of a few available treatment strategies for neurodegenerative dementias such as Alzheimer's disease and related…”
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Naringenin and atherosclerosis: a review of literature by Orhan, Ilkay E, Nabavi, Seyed F, Daglia, Maria, Tenore, Gian C, Mansouri, Kowsar, Nabavi, Seyed M

“…Atherosclerosis is a multifactorial disease mainly caused by deposition of low-density lipoprotein (LD) cholesterol in macrophages of arterial walls…”
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Chemical and molecular aspects on interactions of galanthamine and its derivatives with cholinesterases by Gulcan, Hayrettin O, Orhan, Ilkay E, Sener, Bilge

“…Dual action of galanthamine as potent cholinesterase inhibitor and nicotinic modulator has attracted a great attention to be used in the treatment of AD…”
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Spiro Heterocyclic Compounds as Potential Anti-Alzheimer Agents (Part 2): Their Metal Chelation Capacity, POM Analyses and DFT Studies by Hadda, Taibi B, Deniz, Fatma S S, Orhan, Ilkay E, Zgou, Hsaine, Rauf, Abdur, Mabkhot, Yahia N, Bennani, Brahim, Emam, Dalia R, Kheder, Nabila A, Asayari, Abdulrhman, Muhsinah, Abdullatif B, Maalik, Aneela

“…One of the best methods to treat Alzheimer disease (AD) is through the effective use of cholinesterase inhibitors as vital drugs due to the identification of…”
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Selective cholinesterase inhibitors from Buxus sempervirens L. and their molecular docking studies by Orhan, Ilkay E, Khan, Mahmud T H, Erdem, Sinem A, Kartal, Murat, Sener, Bilge

“…In this work, two alkaloids namely (+)-buxabenzamidienine (1) and (+)-buxamidine (2) were isolated from Buxus sempervirens, using bioassay-guided fractionation…”
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Implications of some selected flavonoids towards Alzheimer's disease with the emphasis on cholinesterase inhibition and their bioproduction by metabolic engineering by Orhan, Ilkay E

“…Flavonoids are one of the most abundant secondary metabolites having a polyphenolic structure in plant and animal species with various desired pharmacological…”
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Phytochemical and Pharmacological Activity Profile of Crataegus oxyacantha L. (Hawthorn) - A Cardiotonic Herb by Orhan, Ilkay Erdogan

“…Crataegus oxyacantha L. (syn. C. rhipidophylla Gand.) (Rosac-eae) is one of the two medicinally recognized hawthorn species in European Pharmacopeia…”
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Blessings in disguise: a review of phytochemical composition and antimicrobial activity of plants belonging to the genus Eryngium by Erdem, Sinem Aslan, Nabavi, Seyed Fazel, Orhan, Ilkay Erdogan, Daglia, Maria, Izadi, Morteza, Nabavi, Seyed Mohammad

“…Medicinal and edible plants play a crucial role in the prevention and/or mitigation of different human diseases from ancient times to today. In folk medicine,…”
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Outstanding effect of the conformational restriction of isoquinolines: hints for the development of optimized antimicrobial agents by Ozcelik, Berrin, Sheikh, Javed, Orhan, Ilkay E., Juneja, Harjeet, Bennani, Brahim, Kerbal, Abdelali, Cavalcanti, S. M. T., Leite, Ana C. L., Ben Hadda, Taibi

“…Conformational restriction constitutes a useful strategy of molecular modification for the design of new potential drug candidates. Herein we present the…”
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