Search Results - "Orfanó, Alessandra"

Structure-guided insights into potential function of novel genetic variants in the malaria vaccine candidate PfRh5 by Mangou, Khadidiatou, Moore, Adam J., Thiam, Laty Gaye, Ba, Aboubacar, Orfanó, Alessandra, Desamours, Ife, Ndegwa, Duncan Ndungu, Goodwin, Justin, Guo, Yicheng, Sheng, Zizhang, Patel, Saurabh D., Diallo, Fatoumata, Sene, Seynabou D., Pouye, Mariama N., Faye, Awa Thioub, Thiam, Alassane, Nunez, Vanessa, Diagne, Cheikh Tidiane, Sadio, Bacary Djilocalisse, Shapiro, Lawrence, Faye, Ousmane, Mbengue, Alassane, Bei, Amy K.

“…The recent stall in the global reduction of malaria deaths has made the development of a highly effective vaccine essential. A major challenge to developing an…”
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Growth arrested live-attenuated Leishmania infantum KHARON1 null mutants display cytokinesis defect and protective immunity in mice by Santi, Ana Maria Murta, Lanza, Juliane Sousa, Tunes, Luiza Guimarães, Fiuza, Jacqueline Araújo, Roy, Gaétan, Orfanó, Alessandra da Silva, de Carvalho, Andréa Teixeira, Frézard, Frédéric, Barros, André Luís Branco de, Murta, Silvane Maria Fonseca, do Monte-Neto, Rubens Lima

“…There is no safe and efficacious vaccine against human leishmaniasis available and live attenuated vaccines have been used as a prophylactic alternative…”
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Differential responses of epithelial cells from urinary and biliary tract to eggs of Schistosoma haematobium and S. mansoni by Nacif-Pimenta, Rafael, da Silva Orfanó, Alessandra, Mosley, Ilana A., Karinshak, Shannon E., Ishida, Kenji, Mann, Victoria H., Coelho, Paulo Marcos Zech, da Costa, José M. Correia, Hsieh, Michael H., Brindley, Paul J., Rinaldi, Gabriel

“…Chronic urogenital schistosomiasis can lead to squamous cell carcinoma of the bladder. The International Agency for Research on Cancer classifies the infection…”
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Phenotypic traits of individuals in a long-term colony of Anopheles (Nyssorhynchus) aquasalis (Diptera: Culicidae) show variable susceptibility to Plasmodium and suggest cryptic speciation by Rodrigues, Nilton Barnabé, Villegas, Luís Eduardo Martinez, Duarte, Ana Paula Marques, Orfanó, Alessandra Silva, dos Anjos Costa, Breno, Nacif Pimenta, Rafael, Lacerda, Marcus V.G., Monteiro, Wuelton M., Secundino, Nágila Francinete Costa, Pimenta, Paulo Filemon Paolucci

“…•An. Aquasalis mosquitoes of a 25 year-established colony keep two phenotypes (30BS and 50BS) based on their 2nd hind-tarsomere scaling patterns.•Transcribed…”
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Schistosoma mansoni in susceptible and resistant snail strains Biomphalaria tenagophila: in vivo tissue response and in vitro hemocyte interactions by Nacif-Pimenta, Rafael, de Mattos, Ana Carolina Alves, Orfanó, Alessandra da Silva, Barbosa, Luciene, Pimenta, Paulo Filemon Paolucci, Coelho, Paulo Marcos Zech

“…Schistosomiasis is a parasitic disease that is highly prevalent, especially in developing countries. Biomphalaria tenagophila is an important invertebrate host…”
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Bacterial diversity of wild-caught Lutzomyia longipalpis (a vector of zoonotic visceral leishmaniasis in Brazil) under distinct physiological conditions by metagenomics analysis by Pires, Ana Clara Araújo Machado, Villegas, Luís Eduardo Martinez, Campolina, Thaís Bonifácio, Orfanó, Alessandra Silva, Pimenta, Paulo Filemon Paolucci, Secundino, Nágila Francinete Costa

“…The leishmaniases are a group of diseases caused by protozoans of the genus Leishmania, which are transmitted by the bite of phlebotomine sand flies. In the…”
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Promising approach to reducing Malaria transmission by ivermectin: Sporontocidal effect against Plasmodium vivax in the South American vectors Anopheles aquasalis and Anopheles darlingi by Pinilla, Yudi T, C P Lopes, Stefanie, S Sampaio, Vanderson, Andrade, Francys S, Melo, Gisely C, Orfanó, Alessandra S, Secundino, Nágila F C, Guerra, Maria G V B, Lacerda, Marcus V G, Kobylinski, Kevin C, Escobedo-Vargas, Karin S, López-Sifuentes, Victor M, Stoops, Craig A, Baldeviano, G Christian, Tarning, Joel, Vasquez, Gissella M, Pimenta, Paulo F P, Monteiro, Wuelton M

“…The mosquito resistance to the insecticides threatens malaria control efforts, potentially becoming a major public health issue. Alternative methods like…”
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Zika virus infection modulates the bacterial diversity associated with Aedes aegypti as revealed by metagenomic analysis by Villegas, Luis E M, Campolina, Thais B, Barnabe, Nilton R, Orfano, Alessandra S, Chaves, Barbara A, Norris, Douglas E, Pimenta, Paulo F P, Secundino, Nagila F C

“…Zika is a re-emerging infection that has been considered a major threat to global public health. Currently at least 100 countries are at risk of Zika virus…”
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The role of the peritrophic matrix and red blood cell concentration in Plasmodium vivax infection of Anopheles aquasalis by Baia-da-Silva, Djane Clarys, Alvarez, Luis Carlos Salazar, Lizcano, Omaira Vera, Costa, Fabio Trindade Maranhão, Lopes, Stefanie Costa Pinto, Orfanó, Alessandra Silva, Pascoal, Denner Oliveira, Nacif-Pimenta, Rafael, Rodriguez, Iria Cabral, Guerra, Maria das Graças Vale Barbosa, Lacerda, Marcus Vinicius Guimarães, Secundino, Nagila Francinete Costa, Monteiro, Wuelton Marcelo, Pimenta, Paulo Filemon Paolucci

“…Plasmodium vivax is predominant in the Amazon region, and enhanced knowledge of its development inside a natural vector, Anopheles aquasalis, is critical for…”
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Ultrastructure of the Antennae and Sensilla of Nyssomyia intermedia (Diptera: Psychodidae), Vector of American Cutaneous Leishmaniasis by de Freitas Fernandes, Fernando, Barletta, Ana Beatriz F., Orfanó, Alessandra S., Pinto, Luciana C., Nacif-Pimenta, Rafael, Miranda, Jose Carlos, Secundino, Nágila F. C., Bahia, Ana Cristina, Pimenta, Paulo F. P.

“…The antennal sensilla and the antenna of females Nyssomyia intermedia, one of the main vectors of American cutaneous leishmaniasis, were studied by scanning…”
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The JAK-STAT pathway controls Plasmodium vivax load in early stages of Anopheles aquasalis infection by Bahia, Ana C, Kubota, Marina S, Tempone, Antonio J, Araújo, Helena R C, Guedes, Bruno A M, Orfanó, Alessandra S, Tadei, Wanderli P, Ríos-Velásquez, Claudia M, Han, Yeon S, Secundino, Nágila F C, Barillas-Mury, Carolina, Pimenta, Paulo F P, Traub-Csekö, Yara M

“…Malaria affects 300 million people worldwide every year and 450,000 in Brazil. In coastal areas of Brazil, the main malaria vector is Anopheles aquasalis, and…”
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Morphological Characterization of the Antennal Sensilla of the Afrotropical Sand Fly, Phlebotomus duboscqi (Diptera: Psychodidae) by Bahia, Ana Cristina, Barletta, Ana Beatriz F., Pinto, Luciana Conceição, Orfanó, Alessandra S., Nacif-Pimenta, Rafael, Volfova, Vera, Petr, Volf, Costa Secundino, Nágila Francinete, Freitas Fernandes, Fernando de, Pimenta, Paulo Filemon P.

“…We investigated by scanning electron microscopy the morphology, distribution, and abundance of antennal sensilla of females Phlebotomus duboscqi sand fly, an…”
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Plasmodium yoelii nigeriensis (N67) Is a Robust Animal Model to Study Malaria Transmission by South American Anopheline Mosquitoes by Orfano, Alessandra S, Duarte, Ana Paula M, Molina-Cruz, Alvaro, Pimenta, Paulo F, Barillas-Mury, Carolina

“…Malaria is endemic in the American continent and the Amazonian rainforest is the region with the highest risk of transmission. However, the lack of suitable…”
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Paratransgenic manipulation of a tsetse microRNA alters the physiological homeostasis of the fly's midgut environment by Yang, Liu, Weiss, Brian L, Williams, Adeline E, Aksoy, Emre, de Silva Orfano, Alessandra, Son, Jae Hak, Wu, Yineng, Vigneron, Aurelien, Karakus, Mehmet, Aksoy, Serap

“…Tsetse flies are vectors of parasitic African trypanosomes, the etiological agents of human and animal African trypanosomoses. Current disease control methods…”
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Microanatomy of the American Malaria Vector Anopheles aquasalis (Diptera: Culicidae: Anophelinae) Midgut: Ultrastructural and Histochemical Observations by Baia-da-Silva, Djane C., Orfanó, Alessandra S., Nacif-Pimenta, Rafael, de Melo, Fabricio F., Guerra, Maria G. V. B., Lacerda, Marcus V. G., Monteiro, Wuelton M., Pimenta, Paulo F. P.

“…The mosquito gut is divided into foregut, midgut, and hindgut. The midgut functions in storage and digestion of the bloodmeal. This study used light, scanning…”
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Dengue and Zika virus infection patterns vary among Aedes aegypti field populations from Belo Horizonte, a Brazilian endemic city by Godoy, Raquel Soares Maia, Felix, Luiza Dos Santos, Orfanó, Alessandra da Silva, Chaves, Bárbara Aparecida, Nogueira, Paula Monalisa, Costa, Breno Dos Anjos, Soares, Aline Silva, Oliveira, Cinthia Catharina Azevedo, Nacif-Pimenta, Rafael, Silva, Breno Mello, Duarte, Ana Paula, Lacerda, Marcus Vinicius Guimarães de, Monteiro, Wuelton Marcelo, Secundino, Nágila Francinete Costa, Pimenta, Paulo Filemon Paolucci

“…Dengue virus (DENV) and Zika virus (ZIKV) belong to the same viral family, the Flaviviridae. They cause recurring threats to the public health systems of…”
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Corrigendum to: Morphological Characterization of the Antennal Sensilla of the Afrotropical Sand Fly, Phlebotomus duboscqi (Diptera: Psychodidae) by Bahia, Ana Cristina, Barletta, Ana Beatriz F, Pinto, Luciana Conceição, Orfanó, Alessandra S, Nacif-Pimenta, Rafael, Volfova, Vera, Petr, Volf, Costa Secundino, Nágila Francinete, de Freitas Fernandes, Fernando, P. Pimenta, Paulo Filemon

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The Midgut Muscle Network of Anopheles aquasalis (Culicidae, Anophelinae): Microanatomy and Structural Modification After Blood Meal and Plasmodium vivax (Haemosporida, Plasmodiidae) Infection by Baia-da-Silva, Djane C., Orfanó, Alessandra S., Nacif-Pimenta, Rafael, Melo, Fabrício Freire de, Simões, Suzan, Cabral, Iria, Lacerda, Marcus Vinicíus Guimarães, Guerra, Maria das Graças Barbosa, Monteiro, Wuelton M., Secundino, Nagila F. C., Pimenta, Paulo F. P.

“…The mosquito midgut is divided into two regions named anterior midgut (AMG) and posterior midgut (PMG). The midgut expands intensely after the blood ingestion…”
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Species-specific escape of Plasmodium sporozoites from oocysts of avian, rodent, and human malarial parasites by Orfano, Alessandra S, Nacif-Pimenta, Rafael, Duarte, Ana P M, Villegas, Luis M, Rodrigues, Nilton B, Pinto, Luciana C, Campos, Keillen M M, Pinilla, Yudi T, Chaves, Bárbara, Barbosa Guerra, Maria G V, Monteiro, Wuelton M, Smith, Ryan C, Molina-Cruz, Alvaro, Lacerda, Marcus V G, Secundino, Nágila F C, Jacobs-Lorena, Marcelo, Barillas-Mury, Carolina, Pimenta, Paulo F P

“…Malaria is transmitted when an infected mosquito delivers Plasmodium sporozoites into a vertebrate host. There are many species of Plasmodium and, in general,…”
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Brazilian Aedes aegypti as a Competent Vector for Multiple Complex Arboviral Coinfections by Rodrigues, Nilton Barnabé, Godoy, Raquel Soares Maia, Orfano, Alessandra Silva, Chaves, Barbara Aparecida, Campolina, Thais Bonifácio, Costa, Breno dos Anjos, Félix, Luíza dos Santos, Silva, Breno Melo, Norris, Douglas Eric, Pimenta, Paulo Filemon Paolucci, Secundino, Nagila Francinete Costa

“…Abstract Background Aedes aegypti is a highly competent vector in the transmission of arboviruses, such as chikungunya, dengue, Zika, and yellow fever viruses,…”
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