Search Results - "Orens, J. B."

High‐Quality CMV‐Specific CD4+ Memory Is Enriched in the Lung Allograft and Is Associated With Mucosal Viral Control by Akulian, J. A., Pipeling, M. R., John, E. R., Orens, J. B., Lechtzin, N., McDyer, J. F.

“…The maintenance of CMV‐specific T cell memory in lung transplant recipients (LTRs) is critical for host defense and allograft durability, particularly in…”
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Lung transplant outcomes: a review of survival, graft function, physiology, health-related quality of life and cost-effectiveness by Studer, S.M, Levy, R.D, McNeil, K, Orens, J.B

“…The success of lung transplantation has improved over time as evidenced by better long-term survival and functional outcomes. Despite the success of this…”
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Patterns and significance of exhaled-breath biomarkers in lung transplant recipients with acute allograft rejection by Studer, S M, Orens, J B, Rosas, I, Krishnan, J A, Cope, K A, Yang, S, Conte, J V, Becker, P B, Risby, T H

“…Obliterative bronchiolitis (OB) remains one of the leading causes of death in lung transplant recipients after 2 years, and acute rejection (AR) of lung…”
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Dysfunctional voltage-gated K+ channels in pulmonary artery smooth muscle cells of patients with primary pulmonary hypertension by YUAN, J. X.-J, ALDINGER, A. M, JUHASZOVA, M, JIAN WANG, CONTE, J. V, GAINE, S. P, ORENS, J. B, RUBIN, L. J

“…Primary pulmonary hypertension (PPH) is a rare disease of unknown cause. Although PPH and secondary pulmonary hypertension (SPH) share many clinical and…”
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CD154 Deficiency Uncouples Allograft CD8+ T‐Cell Effector Function from Proliferation and Inhibits Murine Airway Obliteration by Shah, P. D., West, E. E., Whitlock, A. B., Orens, J. B., McDyer, J. F.

“…Obliterative bronchiolitis (OB) limits the long‐term success of lung transplantation, while T‐cell effector mechanisms in this process remain incompletely…”
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The sensitivity of high-resolution CT in detecting idiopathic pulmonary fibrosis proved by open lung biopsy. A prospective study by Orens, J B, Kazerooni, E A, Martinez, F J, Curtis, J L, Gross, B H, Flint, A, Lynch, 3rd, J P

“…To assess the sensitivity of high-resolution chest computed tomography (HRCT) in detecting idiopathic pulmonary fibrosis proved by biopsy specimen. To…”
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Thoracic Organ Transplantation in the United States, 1995–2004 by Orens, J. B., Shearon, T. H., Freudenburger, R. S., Conte, J. V., Bhorade, S. M., Ardehali, A.

“…This article reviews trends in thoracic organ transplantation based on OPTN/SRTR data from 1995 to 2004. The number of active waiting list patients for heart…”
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The influence of continuous intravenous prostacyclin therapy for primary pulmonary hypertension on the timing and outcome of transplantation by Conte, J V, Gaine, S P, Orens, J B, Harris, T, Rubin, L J

“…Primary pulmonary hypertension (PPH) is a progressive disease with a median survival of less than 3 years from diagnosis. Medical management has typically…”
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The Effect of the Cystic Fibrosis Care Center on Lung Transplant Outcomes by Krishnan, A., Bush, E.L., Chidi, A., Nolley, E., Agbor-Enoh, S., West, N.E., Tallarico, E., Orens, J.B., Ha, J., Shah, P., Segev, D., Massie, A., Higgins, R.S., Merlo, C.A.

“…Since 1961 the Cystic Fibrosis Foundation has designated certain institutions devoted to treating cystic fibrosis (CF) as Cystic Fibrosis Care Centers (CFCC)…”
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Simulated Regionalization of Heart and Lung Transplantation in the United States by Magruder, J. T., Shah, A. S., Crawford, T. C., Grimm, J. C., Kim, B., Orens, J. B., Bush, E. L., Higgins, R. S., Merlo, C. A.

“…We simulated the impact of regionalization of isolated heart and lung transplantation within United Network for Organ Sharing (UNOS) regions. Overall, 12 594…”
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Splenic Irradiation for the Treatment of Severe Antibody‐Mediated Rejection by Orandi, B. J., Lonze, B. E., Jackson, A., Terezakis, S., Kraus, E. S., Alachkar, N., Bagnasco, S. M., Segev, D. L., Orens, J. B., Montgomery, R. A.

“…Patients requiring desensitization prior to renal transplantation are at risk for developing severe antibody‐mediated rejection (AMR) refractory to treatment…”
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Allograft Injury and Outcomes in African American Lung Transplant Recipients by Agbor-Enoh, S., Charya, A., Jang, M., Luikart, H., Shah, P., Matthews, J., Brown, A.W., Timofte, I., Fideli, U., Kong, H., Bhatti, K., Marishta, A., Yang, Y., Tunc, I., Berry, G., Marboe, C., Iacono, A., Nathan, S., Khush, K., Orens, J.B., Valantine, H.

“…African American patients (AA) have poorer outcomes than White patients (W) after heart and kidney transplant. Little is known about differential outcomes in…”
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Impaired beta-adrenergic receptor stimulation of cyclic adenosine monophosphate in human septic shock: association with myocardial hyporesponsiveness to catecholamines by Silverman, H J, Penaranda, R, Orens, J B, Lee, N H

“…To determine whether myocardial hyporesponsiveness to administered catecholamines occurs in human sepsis and whether this phenomenon is associated with…”
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Clinical Outcomes after Pediatric Lung Transplantation at Cystic Fibrosis Care Centers by Chidi, A.P., Krishnan, A., Nolley, E., Agbor-Enoh, S., West, N.E., Tallarico, E., Thaxton, A., Orens, J.B., Ha, J., Shah, P.D., Segev, D., Massie, A., Higgins, R.S., Merlo, C.A., Bush, E.L.

“…Clinical outcomes remain extremely poor for children with cystic fibrosis undergoing lung transplantation. Since 1961, the Cystic Fibrosis Foundation has…”
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Improved Survival after Repeat Lung Transplantation at Cystic Fibrosis Care Centers by Chidi, A.P., Krishnan, A., Nolley, E., Agbor-Enoh, S., West, N.E., Tallarico, E., Thaxton, A., Orens, J.B., Ha, J.S., Shah, P.D., Segev, D., Massie, A., Higgins, R.S., Merlo, C.A., Bush, E.L.

“…Patients who undergo repeat lung transplantation (LT) are at high risk for perioperative complications. The complexity of their care requires specialized…”
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Pleuropulmonary manifestations of systemic lupus erythematosus by Orens, J B, Martinez, F J, Lynch, 3rd, J P

“…The pleuropulmonary manifestation of systemic lupus erythematous (SLE) are pleuritis, acute lupus pneumonitis, chronic interstitial lung disease with fibrosis,…”
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Endobronchial ultrasound-guided needle aspiration of mediastinal adenopathy by Shannon, J J, Bude, R O, Orens, J B, Becker, F S, Whyte, R I, Rubin, J M, Quint, L E, Martinez, F J

“…We conducted a randomized, controlled trial to prospectively confirm that ultrasound-directed transbronchial needle aspiration (USTBNA) results in: (1)…”
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Lung transplantation for pulmonary hypertension by Orens, J B

“…Lung transplantation is an accepted therapeutic intervention for patients with pulmonary arterial hypertension (PAH) who fail medical therapy. Highly selected…”
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High dose rate brachytherapy to prevent recurrent benign hyperplasia in lung transplant bronchi: theoretical and clinical considerations by Kennedy, A S, Sonett, J R, Orens, J B, King, K

“…Significant anastomotic stenosis and malacia is reported to affect 7% to 15% of lung transplant recipients. Laser debridement, dilation and stenting can be…”
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Recurrence of sarcoidosis following bilateral allogeneic lung transplantation by Martinez, F J, Orens, J B, Deeb, M, Brunsting, L A, Flint, A, Lynch, 3rd, J P

“…We report the first case of recurrent sarcoidosis manifested by clinical symptoms, radiographic abnormalities, and pathologic changes in a patient following…”
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