Search Results - "Orengo, M A"

The role of CEA, CYFRA21-1 and NSE in monitoring tumor response to Nivolumab in advanced non-small cell lung cancer (NSCLC) patients by Dal Bello, M G, Filiberti, R A, Alama, A, Orengo, A M, Mussap, M, Coco, S, Vanni, I, Boccardo, S, Rijavec, E, Genova, C, Biello, F, Barletta, G, Rossi, G, Tagliamento, M, Maggioni, C, Grossi, F

“…CEA, CYFRA21-1 and NSE are tumor markers used for monitoring the response to chemotherapy in advanced adenocarcinoma, squamous cell carcinoma and small-cell…”
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A multi-DNA preventive vaccine for p53/Neu-driven cancer syndrome by De Giovanni, C, Nicoletti, G, Palladini, A, Croci, S, Landuzzi, L, Antognoli, A, Murgo, A, Astolfi, A, Ferrini, S, Fabbi, M, Orengo, A M, Amici, A, Penichet, M L, Aurisicchio, L, Iezzi, M, Musiani, P, Nanni, P, Lollini, P-L

“…The highly aggressive cancer syndrome of female mice carrying a p53 knockout allele and a rat HER-2/neu (Neu) transgene (BALB-p53Neu) can be prevented by a…”
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P58 molecules as putative receptors for major histocompatibility complex (MHC) class I molecules in human natural killer (NK) cells. Anti-p58 antibodies reconstitute lysis of MHC class I-protected cells in NK clones displaying different specificities by MORETTA, A, VITALE, M, BOTTINO, C, ORENGO, A. M, MORELLI, L, AUGUGLIARO, R, BARBARESI, M, CICCONE, E, MORETTA, L

“…Human CD3-16+56+ natural killer (NK) cells have been shown to display a clonally distributed ability to recognize major histocompatibility complex (MHC) class…”
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Establishment of four new mesothelioma cell lines: characterization by ultrastructural and immunophenotypic analysis by Orengo, AM, Spoletini, L, Procopio, A, Favoni, RE, De Cupis, A, Ardizzoni, A, Castagneto, B, Ribotta, M, Betta, PG, Ferrini, S, Mutti, L

“…The aim of this study was to assess the biological characteristics of four new malignant mesothelioma (MM) cell lines. Since simian virus (SV)40 sequences have…”
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Socioeconomic status and survival of gastric cancer patients by FONTANA, V, DECENSI, A, ORENGO, M. A, PARODI, S, TORRISI, R, PUNTONI, R

“…Survival differences in cancer patients according to socioeconomic status (SES) have been reported for several organs, but the relationship with gastric cancer…”
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Involvement of HLA class I alleles in natural killer (NK) cell-specific functions : expression of HLA-Cw3 confers selective protection from lysis by alloreactive NK clones displaying a defined specificity (specificity 2) by CICCONE, E, PENDE, D, MORETTA, L, VIALE, O, THAN, A, DI DONATO, C, ORENGO, A. M, BIASSONI, R, VERDIANI, S, AMOROSO, A, MORETTA, A

“…This study was designed to identify the target molecules of the natural killer (NK) cell-mediated recognition of normal allogeneic target cells. As previously…”
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Bcl2, p53 and clinical outcome in a series of 138 operable breast cancer patients by Castiglione, F, Sarotto, I, Fontana, V, Destefanis, M, Venturino, A, Ferro, S, Cardaropoli, S, Orengo, M A, Porcile, G

“…Medical oncologists are increasingly interested in identifying reliable prognostic factors for breast cancer in order to distinguish subsets of breast cancer…”
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Reciprocal expression of CD70 and of its receptor, CD27, in human long term-activated T and natural killer (NK) cells : inverse regulation by cytokines and role in induction of cytotoxicity by ORENGO, A. M, CANTONI, C, NEGLIA, F, BIASSONI, R, FERRINI, S

“…By transfection of COS cells with an expression vector containing CD70 cDNA we demonstrate that two previously described MoAbs (ED6 and LD6) recognize CD70. By…”
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Long-term effects of fenretinide on retinal function by Decensi, A., Fontana, V., Fioretto, M., Rondanina, G., Torrisi, R., Orengo, M.A., Costa, A.

“…The long-term effects of the synthetic retinoid fenretinide (4-HPR) on retinal function were studied by electroretinogram (ERG) in 24 women treated for a…”
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IL-21 induces tumor rejection by specific CTL and IFN-gamma-dependent CXC chemokines in syngeneic mice by Di Carlo, Emma, Comes, Alberto, Orengo, Anna Maria, Rosso, Ombretta, Meazza, Raffaella, Musiani, Piero, Colombo, Mario P, Ferrini, Silvano

“…IL-21 is an immune-stimulatory four alpha helix cytokine produced by activated T cells. To study the in vivo antitumor activities of IL-21, TS/A murine mammary…”
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Primary human mesothelioma cells express class II MHC, ICAM‐1 and B7–2 and can present recall antigens to autologous blood lymphocytes by Mutti, Luciano, Valle, Maria T., Balbi, Bruno, Orengo, Anna M., Lazzaro, Antonio, Alciato, Paolo, Gatti, Emiliano, Betta, Pier G., Pozzi, Ernesto

“…Mesothelioma cells (MMc) are considered to be weakly immunogenic and the experimental approaches attempting to induce an immune response against these cells…”
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Analysis of IL-2 receptor expression and of the biological effects of IL-2 gene transfection in small-cell lung cancer by MEAZZA, R, MARCIANO, S, SFORZINI, S, ORENGO, A. M, COPPOLECCHIA, M, MUSIANI, P, ARDIZZONI, A, SANTI, L, AZZARONE, B, FERRINI, S

“…We have analysed the expression of interleukin-2 receptor (IL-2R) on a panel of small-cell lung cancer (SCLC) cell lines. None of the 11 SCLC cell lines…”
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The synthetic retinoid fenretinide lowers plasma insulin-like growth factor I levels in breast cancer patients by TORRISI, R, PENSA, F, ORENGO, M. A, CATSAFADOS, E, PONZANI, P, BOCCARDO, F, COSTA, A, DECENSI, A

“…We studied the effect of fenretinide [N-(4-hydroxyphenyl)retinamide (4-HPR)], a synthetic analogue of retinoic acid, on plasma insulin-like growth factor I…”
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Effect of the synthetic retinoid fenretinide on dark adaptation and the ocular surface by Decensi, A, Torrisi, R, Polizzi, A, Gesi, R, Brezzo, V, Rolando, M, Rondanina, G, Orengo, M A, Formelli, F, Costa, A

“…Fenretinide, a synthetic derivative of retinoic acid, is under study in clinical trials for the prevention of breast, skin basal cell, bladder, and oral cancer…”
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The Natural Killer-Related Receptor for HLA-C Expressed on T Cells From CD3+ Lymphoproliferative Disease of Granular Lymphocytes Displays Either Inhibitory or Stimulatory Function by Cambiaggi, Anna, Orengo, Anna Maria, Meazza, Raffaella, Sforzini, Sabrina, Tazzari, Pier Luigi, Lauria, Francesco, Raspadori, Donatella, Zambello, Renato, Semenzato, Gianpietro, Moretta, Lorenzo, Ferrini, Silvano

“…Four patients with lymphoproliferative disease of granular lymphocytes (LDGL) coexpressing CD3 and the natural killer (NK)-related “p58” receptor for HLA-C…”
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Tumor rejection by gene transfer of the MHC class II transactivator in murine mammary adenocarcinoma cells by Meazza, Raffaella, Comes, Alberto, Orengo, Anna M., Ferrini, Silvano, Accolla, Roberto S.

“…The murine mammary adenocarcinoma cell line TS/A is a highly malignant MHC class II‐negative tumor. We show that transfection of TS/A cells with the MHC class…”
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AIDS Related Neoplasms in Genoa, Italy by Gabutti, Giovanni, Vercelli, Marina, De Rosa, Maria-Grazia, Orengo, Maria-Antonietta, Casella, Claudia, Garrone, Elsa, Orlandini, Cinzia, Piersantelli, Nicolò, Torresin, Augusta, Rizzo, Fortunato, Morandi, Norberto, Crovari, Pietro

“…The study defines the epidemiological characteristics of HIV-infection in the population of Genoa and estimates the entity of AIDS-cancer association. The…”
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Evidence of a natural killer (NK) cell repertoire for (allo) antigen recognition : definition of five distinct NK-determined allospecificities in humans by CICCONE, E, PENDE, D, VIALE, O, DI DONATO, C, TRIPODI, G, ORENGO, A. M, GUARDIOLA, J, MORETTA, A, MORETTA, L

“…Previous studies indicated that CD3-CD16+ natural killer (NK) cells are capable of specific alloantigen recognition. Thus, alloreactive NK clones lysed normal…”
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CD69-mediated pathway of lymphocyte activation : anti-CD69 monoclonal antibodies trigger the cytolytic activity of different lymphoid effector cells with the exception of cytolytic T lymphocytes expressing T cell receptor α/β by MORETTA, A, POGGI, A, PENDE, D, TRIPODI, G, ORENGO, A. M, PELLA, N, AUGUGLIARO, R, BOTTINO, C, CICCONE, E, MORETTA, L

“…The effect of anti-CD69 monoclonal antibodies (mAbs) on the induction of the cytolytic activity in different types of lymphoid effector cells has been…”
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Tumor Cells Engineered with IL-12 and IL-15 Genes Induce Protective Antibody Responses in Nude Mice by Orengo, Anna Maria, Di Carlo, Emma, Comes, Alberto, Fabbi, Marina, Piazza, Tiziana, Cilli, Michele, Musiani, Piero, Ferrini, Silvano

“…IL-12 and IL-15 stimulate T, B, and NK cell functions through independent mechanisms, and cooperative effects of these cytokines have been reported. The human…”
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