Search Results - "Orem, Ben C."

IP3R-mediated intra-axonal Ca2+ release contributes to secondary axonal degeneration following contusive spinal cord injury by Orem, Ben C., Rajaee, Arezoo, Stirling, David P.

“…Secondary axonal loss contributes to the persistent functional disability following trauma. Consequently, preserving axons following spinal cord injury (SCI)…”
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Inhibiting store-operated calcium entry attenuates white matter secondary degeneration following SCI by Orem, Ben C., Partain, Steven B., Stirling, David P.

“…Axonal degeneration plays a key role in the pathogenesis of numerous neurological disorders including spinal cord injury. After the irreversible destruction of…”
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Intracellular calcium release through IP3R or RyR contributes to secondary axonal degeneration by Orem, Ben C., Pelisch, Nicolas, Williams, Joshua, Nally, Jacqueline M., Stirling, David P.

“…Severed CNS axons often retract or dieback away from the injury site and fail to regenerate. The precise mechanisms underlying acute axonal dieback and…”
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Direct Ryanodine Receptor-2 Knockout in Primary Afferent Fibers Modestly Affects Neurological Recovery after Contusive Spinal Cord Injury by Orem, Ben C., Morehouse, Johnny R., Ames, Spencer, Burke, Darlene A., Magnuson, David S.K., Stirling, David P.

“…Neuronal ryanodine receptors (RyR) release calcium from internal stores and play a key role in synaptic plasticity, learning, and memory. Dysregulation of RyR…”
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Inhibiting Calcium Release from Ryanodine Receptors Protects Axons after Spinal Cord Injury by Orem, Ben C, Rajaee, Arezoo, Stirling, David P

“…Ryanodine receptors (RyRs) mediate calcium release from calcium stores and have been implicated in axonal degeneration. Here, we use an intravital imaging…”
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The toll-like receptor 2 agonist Pam3CSK4 is neuroprotective after spinal cord injury by Stivers, Nicole S., Pelisch, Nicolas, Orem, Ben C., Williams, Joshua, Nally, Jacqueline M., Stirling, David P.

“…Microglia/macrophage activation and recruitment following spinal cord injury (SCI) is associated with both detrimental and reparative functions. Stimulation of…”
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Intracellular calcium release through IP 3 R or RyR contributes to secondary axonal degeneration by Orem, Ben C, Pelisch, Nicolas, Williams, Joshua, Nally, Jacqueline M, Stirling, David P

“…Severed CNS axons often retract or dieback away from the injury site and fail to regenerate. The precise mechanisms underlying acute axonal dieback and…”
Get full text

IP 3 R-mediated intra-axonal Ca 2+ release contributes to secondary axonal degeneration following contusive spinal cord injury by Orem, Ben C, Rajaee, Arezoo, Stirling, David P

“…Secondary axonal loss contributes to the persistent functional disability following trauma. Consequently, preserving axons following spinal cord injury (SCI)…”
Get full text