Search Results - "Orellana, Renan A."

Intermittent bolus feeding has a greater stimulatory effect on protein synthesis in skeletal muscle than continuous feeding in neonatal pigs by Gazzaneo, María C, Suryawan, Agus, Orellana, Renán A, Torrazza, Roberto Murgas, El-Kadi, Samer W, Wilson, Fiona A, Kimball, Scot R, Srivastava, Neeraj, Nguyen, Hanh V, Fiorotto, Marta L, Davis, Teresa A

“…Orogastric tube feeding, using either continuous or intermittent bolus delivery, is common in infants for whom normal feeding is contraindicated. To compare…”
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Physician Awareness and Management Practices of Fluid Overload in Critically Ill Children by Branco, Ricardo Garcia, Orellana, Renán A

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Nutrition Support among Critically Ill Children with AKI by Ursula G. Kyle, Ayse Akcan-Arikan, Renán A. Orellana, Jorge A. Coss-Bu

“…Critically ill children are at high risk of underfeeding and AKI, which may lead to further nutritional deficiencies. This study aimed to determine the…”
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Leucine stimulates protein synthesis in skeletal muscle of neonatal pigs by enhancing mTORC1 activation by Suryawan, Agus, Jeyapalan, Asumthia S, Orellana, Renan A, Wilson, Fiona A, Nguyen, Hanh V, Davis, Teresa A

“…Skeletal muscle in the neonate grows at a rapid rate due in part to an enhanced sensitivity to the postprandial rise in amino acids, particularly leucine. To…”
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Feeding rapidly stimulates protein synthesis in skeletal muscle of neonatal pigs by enhancing translation initiation by Wilson, Fiona A, Suryawan, Agus, Orellana, Renán A, Kimball, Scot R, Gazzaneo, Maria C, Nguyen, Hanh V, Fiorotto, Marta L, Davis, Teresa A

“…Food consumption increases protein synthesis in most tissues by promoting translation initiation, and in the neonate, this increase is greatest in skeletal…”
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Stimulation of muscle protein synthesis by prolonged parenteral infusion of leucine is dependent on amino acid availability in neonatal pigs by Wilson, Fiona A, Suryawan, Agus, Gazzaneo, Maria C, Orellana, Renán A, Nguyen, Hanh V, Davis, Teresa A

“…The postprandial rise in amino acids, particularly leucine, stimulates muscle protein synthesis in neonates. Previously, we showed that a 1-h infusion of…”
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Amino acids, independent of insulin, attenuate skeletal muscle autophagy in neonatal pigs during endotoxemia by Hernandez-García, Adriana, Manjarín, Rodrigo, Suryawan, Agus, Nguyen, Hanh V., Davis, Teresa A., Orellana, Renán A.

“…Background: Sepsis induces loss of skeletal muscle mass by activating the ubiquitin proteasome (UPS) and autophagy systems. Although muscle protein synthesis…”
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Feasibility of Achieving Nutritional Adequacy in Critically Ill Children with Critical Neurological Illnesses (CNIs)?-A Quaternary Hospital Experience by Mansour, Marwa, Knebusch, Nicole, Daughtry, Jennifer, Fogarty, Thomas P, Lam, Fong Wilson, Orellana, Renan A, Lai, Yi-Chen, Erklauer, Jennifer, Coss-Bu, Jorge A

“…The literature on the nutritional needs and outcomes of critically ill children is scarce, especially on those with critical neurological illnesses (CNIs)…”
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Differential Regulation of Protein Synthesis and mTOR Signaling in Skeletal Muscle and Visceral Tissues of Neonatal Pigs After a Meal by Gazzaneo, María C, Orellana, Renán A, Suryawan, Agus, Tuckow, Alexander P, Kimball, Scot R, Wilson, Fiona A, Nguyen, Hanh V, Torrazza, Roberto M, Fiorotto, Marta L, Davis, Teresa A

“…Protein synthesis (PS) increases after a meal in neonates, but the time course of the changes in PS in different tissues after a meal is unknown. We aimed to…”
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Activation by insulin and amino acids of signaling components leading to translation initiation in skeletal muscle of neonatal pigs is developmentally regulated by Suryawan, Agus, Orellana, Renan A, Nguyen, Hanh V, Jeyapalan, Asumthia S, Fleming, Jillian R, Davis, Teresa A

“…Insulin and amino acids act independently to stimulate protein synthesis in skeletal muscle of neonatal pigs, and the responses decrease with development. The…”
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Glucose stimulates protein synthesis in skeletal muscle of neonatal pigs through an AMPK- and mTOR-independent process by Jeyapalan, Asumthia S, Orellana, Renan A, Suryawan, Agus, O'Connor, Pamela M J, Nguyen, Hanh V, Escobar, Jeffery, Frank, Jason W, Davis, Teresa A

“…Skeletal muscle protein synthesis is elevated in neonates in part due to an enhanced response to the rise in insulin and amino acids after eating. In vitro…”
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Pediatric Critical Care Transport: Survey of Current State in Latin America. Latin American Society of Pediatric Intensive Care Transport Committee by Yock-Corrales, Adriana, Casson, Nils, Sosa-Soto, Giordano, Orellana, Renan A.

“…Transport of the critically ill and injured pediatric patient often represents a challenge especially in resource-limited setting. The regional hospitals in…”
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Leucine supplementation of a low-protein meal increases skeletal muscle and visceral tissue protein synthesis in neonatal pigs by stimulating mTOR-dependent translation initiation by Murgas Torrazza, Roberto, Suryawan, Agus, Gazzaneo, Maria C, Orellana, Renán A, Frank, Jason W, Nguyen, Hanh V, Fiorotto, Marta L, El-Kadi, Samer, Davis, Teresa A

“…Protein synthesis and eukaryotic initiation factor (eIF) activation are increased in skeletal muscle of neonatal pigs parenterally infused with amino acids…”
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Leucine supplementation stimulates protein synthesis and reduces degradation signal activation in muscle of newborn pigs during acute endotoxemia by Hernandez-García, Adriana D, Columbus, Daniel A, Manjarín, Rodrigo, Nguyen, Hanh V, Suryawan, Agus, Orellana, Renán A, Davis, Teresa A

“…Sepsis disrupts skeletal muscle proteostasis and mitigates the anabolic response to leucine (Leu) in muscle of mature animals. We have shown that Leu…”
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Endotoxemia reduces skeletal muscle protein synthesis in neonates by Orellana, Renan A, O'Connor, Pamela M J, Nguyen, Hanh V, Bush, Jill A, Suryawan, Agus, Thivierge, M Carole, Fiorotto, Marta L, Davis, Teresa A

“…Protein synthesis in skeletal muscle is reduced by as much as 50% as early as 4 h after a septic challenge in adults. However, the effect of sepsis on muscle…”
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Intermittent bolus feeding promotes greater lean growth than continuous feeding in a neonatal piglet model by El-Kadi, Samer W, Boutry, Claire, Suryawan, Agus, Gazzaneo, Maria C, Orellana, Renán A, Srivastava, Neeraj, Nguyen, Hanh V, Kimball, Scot R, Fiorotto, Marta L, Davis, Teresa A

“…Orogastric tube feeding is indicated in neonates with an impaired ability to ingest food normally and can be administered with an intermittent bolus or…”
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Leucine pulses enhance skeletal muscle protein synthesis during continuous feeding in neonatal pigs by Boutry, Claire, El-Kadi, Samer W, Suryawan, Agus, Wheatley, Scott M, Orellana, Renán A, Kimball, Scot R, Nguyen, Hanh V, Davis, Teresa A

“…Infants unable to maintain oral feeding can be nourished by orogastric tube. We have shown that orogastric continuous feeding restricts muscle protein…”
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Pulsatile delivery of a leucine supplement during long-term continuous enteral feeding enhances lean growth in term neonatal pigs by Boutry, Claire, El-Kadi, Samer W, Suryawan, Agus, Steinhoff-Wagner, Julia, Stoll, Barbara, Orellana, Renán A, Nguyen, Hanh V, Kimball, Scot R, Fiorotto, Marta L, Davis, Teresa A

“…Neonatal pigs are used as a model to study and optimize the clinical treatment of infants who are unable to maintain oral feeding. Using this model, we have…”
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Perioperative nutritional support and malnutrition in infants and children with congenital heart disease by Toole, Benjamin J, Toole, Lindsay E, Kyle, Ursula G, Cabrera, Antonio G, Orellana, Renán A, Coss-Bu, Jorge A

“…To assess the effect of nutritional status and cardiovascular risk on hospital outcomes after congenital heart surgery in infants and children. Retrospective…”
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Protein synthesis in skeletal muscle of neonatal pigs is enhanced by administration of β-hydroxy-β-methylbutyrate by Wheatley, Scott M, El-Kadi, Samer W, Suryawan, Agus, Boutry, Claire, Orellana, Renán A, Nguyen, Hanh V, Davis, Steven R, Davis, Teresa A

“…Many low-birth-weight infants experience failure to thrive. The amino acid leucine stimulates protein synthesis in skeletal muscle of the neonate, but less is…”
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