Search Results - "Orekhov, A N"

Vascular smooth muscle cell in atherosclerosis by Chistiakov, D. A., Orekhov, A. N., Bobryshev, Y. V.

“…Vascular smooth muscle cells (VSMCs) exhibit phenotypic and functional plasticity in order to respond to vascular injury. In case of the vessel damage, VSMCs…”
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Effects of shear stress on endothelial cells: go with the flow by Chistiakov, D. A., Orekhov, A. N., Bobryshev, Y. V.

“…Haemodynamic forces influence the functional properties of vascular endothelium. Endothelial cells (ECs) have a variety of receptors, which sense flow and…”
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Lipid composition of circulating multiple-modified low density lipoprotein by Zakiev, E R, Sukhorukov, V N, Melnichenko, A A, Sobenin, I A, Ivanova, E A, Orekhov, A N

“…Atherogenic modified low- density lipoprotein (LDL) induces pronounced accumulation of cholesterol and lipids in the arterial wall, while native LDL seems to…”
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Rehmanniae Radix Preparata suppresses bone loss and increases bone strength through interfering with canonical Wnt/β-catenin signaling pathway in OVX rats by Liu, C., Wang, L., Zhu, R., Liu, H., Ma, R., Chen, B., Li, L., Guo, Y., Jia, Q., Shi, S., Zhao, D., Mo, F., Zhao, B., Niu, J., Fu, M., Orekhov, A.N., Brömme, D., Gao, S., Zhang, D.

“…Summary Rehmanniae Radix Preparata (RRP) improves bone quality in OVX rats through the regulation of bone homeostasis via increasing osteoblastogenesis and…”
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Sialic acid as the potential link between lipid metabolism and inflammation in the pathogenesis of atherosclerosis by Poznyak, A V, Kashirskikh, D A, Postnov, A Y, Popov, M A, Sukhorukov, V N, Orekhov, A N

“…In the modern world, cardiovascular diseases have a special place among the most common causes of death. Naturally, this widespread problem cannot escape the…”
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An update on the tools for creating transgenic animal models of human diseases - focus on atherosclerosis by Volobueva, A S, Orekhov, A N, Deykin, A V

“…Animal models of diseases are invaluable tools of modern medicine. More than forty years have passed since the first successful experiments and the spectrum of…”
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Peculiarities of cell composition and cell proliferation in different type atherosclerotic lesions in carotid and coronary arteries by Orekhov, A.N, Andreeva, E.R, Andrianova, I.V, Bobryshev, Y.V

“…Abstract Increased cell proliferation in early atherosclerotic lesions is recognized as an essential event in atherogenesis but the levels of cell…”
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Contribution of neovascularization and intraplaque haemorrhage to atherosclerotic plaque progression and instability by Chistiakov, D. A., Orekhov, A. N., Bobryshev, Y. V.

“…Atherosclerosis is a continuous pathological process that starts early in life and progresses frequently to unstable plaques. Plaque rupture leads to…”
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The biological activity of high-density lipoprotein fractions and their role in the development of cardiovascular diseases by Babintseva, Ya D, Camont, L, Chapman, J, Lhomme, M, Karagodin, V P, Kontush, A, Orekhov, A N

“…Increasing the human plasma concentration of high-density lipoproteins (HDL) may be part of strategy for control of cardiovascular diseases (CVD). HDL…”
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Epigenetic factors in atherogenesis: MicroRNA by Smirnova, A. V., Sukhorukov, V. N., Karagodin, V. P., Orekhov, A. N.

“…MicroRNAs (miRNAs) are small (~22 nucleotides in length) noncoding RNA sequences regulating gene expression at the posttranscriptional level. MicroRNAs bind…”
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The complexity of cell composition of the intima of large arteries: focus on pericyte-like cells by Orekhov, Alexander N, Bobryshev, Yuri V, Chistiakov, Dimitry A

“…Pericytes, which are also known as Rouget cells or perivascular cells, are considered to represent a likely distinct pool of vascular cells that are extremely…”
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Animal models of human atherosclerosis: current progress by Poznyak, A V, Silaeva, Y Y, Orekhov, A N, Deykin, A V

“…Atherosclerosis retains the leading position among the causes of global morbidity and mortality worldwide, especially in the industrialized countries. Despite…”
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Coordination in gene expression during atherogenesis by Shchelkunova, T. A., Morozov, I. A., Rubtsov, P. M., Samokhodskaya, L. M., Sobenin, I. A., Orekhov, A. N., Smirnov, A. N.

“…General tendencies in the regulation of gene expression during atherogenesis were investigated using correlation analysis for 34 mRNA species of several…”
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Impaired tolerance of monocyte-macrophages to lipopolysaccharide in patients with coronary atherosclerosis by Chegodaev, E. S., Nikiforov, N. G., Popov, M. A., Shumakov, D. V., Zybin, D. I., Orekhov, A. N.

“…Atherosclerosis is a chronic disease in which lipids, cells and various proteins accumulate in the walls of the arteries, forming atherosclerotic plaques. The…”
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Phytoestrogen‐Rich Natural Preparation for Treatment of Climacteric Syndrome and Atherosclerosis Prevention in Perimenopausal Women by Kirichenko, T. V., Myasoedova, V. A., Orekhova, V. A., Ravani, A. L., Nikitina, N. A., Grechko, A. V., Sobenin, I. A., Orekhov, A. N.

“…The present study evaluated the risks and benefits of phytoestrogen treatment in healthy perimenopausal women in relation to the dynamics of climacteric…”
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Low-density lipoprotein modification occurring in human plasma: Possible mechanism of in vivo lipoprotein desialylation as a primary step of atherogenic modification by Tertov, V.V, Kaplun, V.V, Sobenin, I.A, Orekhov, A.N

“…We previously found in human blood a fraction of low-density lipoprotein (LDL) that is characterized by a reduced content of sialic acid. Desialylated LDL also…”
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Proinflammatory Activation of Monocytes in Patients with Immunoinflammatory Rheumatic Diseases by Bogatyreva, A. I., Gerasimova, E. V., Kirichenko, T. V., Markina, Yu. V., Popkova, T. V., Shalygina, M. V., Tolstik, T. V., Markin, A. M., Orekhov, A. N.

“…The pathogenesis of immunoinflammatory rheumatic diseases (IRDs) is based on chronic inflammation, one of the key mechanisms of which may be abnormal…”
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Deglycosylation of apo B-containing lipoproteins increase their ability to aggregate and to promote intracellular cholesterol accumulation in vitro by Aksenov, D. V., Medvedeva, L. A., Skalbe, T. A., Sobenin, I. A., Tertov, V. V., Gabbasov, Z. A., Popov, E. V., Orekhov, A. N.

“…Sub-fractions of all apo B-100 containing lipoproteins (low density lipoproteins, very low density lipoproteins and intermediate density lipoproteins) with…”
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Pro-inflammatory activation of monocytes in patients with immunoinflammatory rheumatic diseases by Bogatyreva, A. I., Gerasimova, E. V., Kirichenko, T. V., Markina, Yu. V., Popkova, T. V., Shalygina, M. V., Tolstik, T. V., Markin, A. M., Orekhov, A. N.

“…The pathogenesis of immunoinflammatory rheumatic diseases (IRDs) is based on chronic inflammation, one of the key mechanisms of which may be abnormal…”
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Correction to: Rehmanniae Radix Preparata suppresses bone loss and increases bone strength through interfering with canonical Wnt/β-catenin signaling pathway in OVX rats by Liu, C., Wang, L., Zhu, R., Liu, H., Ma, R., Chen, B., Li, L., Guo, Y., Jia, Q., Shi, S., Zhao, D., Mo, F., Zhao, B., Niu, J., Fu, M., Orekhov, A. N., Brömme, D., Gao, S., Zhang, D.

“…There was a mistake in the part of OVX rats model and RRP intervention in the original publication…”
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