Search Results - "Orefice, Nicola S."
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miRNA profile is altered in a modified EAE mouse model of multiple sclerosis featuring cortical lesions
Published in eLife (17-09-2020)“…Cortical lesions represent a hallmark of multiple sclerosis and are proposed as a predictor of disease severity. microRNAs are suggested to be important…”
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2
ATG9A regulates proteostasis through reticulophagy receptors FAM134B and SEC62 and folding chaperones CALR and HSPB1
Published in iScience (23-04-2021)“…The acetylation of ATG9A within the endoplasmic reticulum (ER) lumen regulates the induction of reticulophagy. ER acetylation is ensured by AT-1/SLC33A1, a…”
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Oral Palmitoylethanolamide Treatment Is Associated with Reduced Cutaneous Adverse Effects of Interferon-β1a and Circulating Proinflammatory Cytokines in Relapsing–Remitting Multiple Sclerosis
Published in Neurotherapeutics (01-04-2016)“…Palmitoylethanolamide (PEA) is an endogenous lipid mediator known to reduce pain and inflammation. However, only limited clinical studies have evaluated the…”
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4
Oral Palmitoylethanolamide Treatment Is Associated with Reduced Cutaneous Adverse Effects of Interferon- beta 1a and Circulating Proinflammatory Cytokines in Relapsing-Remitting Multiple Sclerosis
Published in Neurotherapeutics (01-04-2016)“…Palmitoylethanolamide (PEA) is an endogenous lipid mediator known to reduce pain and inflammation. However, only limited clinical studies have evaluated the…”
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Journal Article -
5
miR-92a-3p and miR-320a are Upregulated in Plasma Neuron-Derived Extracellular Vesicles of Patients with Frontotemporal Dementia
Published in Molecular neurobiology (14-08-2024)“…Despite the efforts to identify fluid biomarkers to improve diagnosis of Frontotemporal dementia (FTD), only a few candidates have been described in recent…”
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βAPP Processing Drives Gradual Tau Pathology in an Age-Dependent Amyloid Rat Model of Alzheimer’s Disease
Published in Cerebral cortex (New York, N.Y. 1991) (01-11-2018)“…Abstract The treatment of Alzheimer’s disease (AD) remains challenging and requires a better in depth understanding of AD progression. Particularly, the link…”
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The IFN- beta 1b effect on Cu Zn superoxide dismutase (SOD1) in peripheral mononuclear blood cells of relapsing-remitting multiple sclerosis patients and in neuroblastoma SK-N-BE cells
Published in Brain research bulletin (01-09-2015)“…Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease leading to axonal injury. Even if the etiology of MS is still unknown the disease…”
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The IFN-β 1b effect on Cu Zn superoxide dismutase (SOD1) in peripheral mononuclear blood cells of relapsing-remitting multiple sclerosis patients and in neuroblastoma SK-N-BE cells
Published in Brain research bulletin (01-09-2015)“…Highlights • SOD1 in CSF and in PBMC of RR-MS patients is reduced compared to control subjects. • IFN β 1b therapy causes an increase of intracellular SOD1 and…”
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Oral Palmitoylethanolamide Treatment Is Associated with Reduced Cutaneous Adverse Effects of Interferon-[beta]1a and Circulating Proinflammatory Cytokines in Relapsing-Remitting Multiple Sclerosis
Published in Neurotherapeutics (01-04-2016)“…Issue Title: Targeting Neural Circuits to Restore Function Palmitoylethanolamide (PEA) is an endogenous lipid mediator known to reduce pain and inflammation…”
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