Search Results - "Orecchioni, Marco"

Macrophage Polarization: Different Gene Signatures in M1(LPS+) vs. Classically and M2(LPS-) vs. Alternatively Activated Macrophages by Orecchioni, Marco, Ghosheh, Yanal, Pramod, Akula Bala, Ley, Klaus

“…Macrophages are found in tissues, body cavities, and mucosal surfaces. Most tissue macrophages are seeded in the early embryo before definitive hematopoiesis…”
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Graphene as cancer theranostic tool: progress and future challenges by Orecchioni, Marco, Cabizza, Roberto, Bianco, Alberto, Delogu, Lucia Gemma

“…Nowadays cancer remains one of the main causes of death in the world. Current diagnostic techniques need to be improved to provide earlier diagnosis and…”
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Olfactory receptors in macrophages and inflammation by Orecchioni, Marco, Matsunami, Hiroaki, Ley, Klaus

“…Olfactory receptors (ORs) that bind odorous ligands are the largest family of G-protein-coupled receptors. In the olfactory epithelium, approximately 400 and…”
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Single-cell mass cytometry and transcriptome profiling reveal the impact of graphene on human immune cells by Orecchioni, Marco, Bedognetti, Davide, Newman, Leon, Fuoco, Claudia, Spada, Filomena, Hendrickx, Wouter, Marincola, Francesco M., Sgarrella, Francesco, Rodrigues, Artur Filipe, Ménard-Moyon, Cécilia, Cesareni, Gianni, Kostarelos, Kostas, Bianco, Alberto, Delogu, Lucia G

“…Understanding the biomolecular interactions between graphene and human immune cells is a prerequisite for its utilization as a diagnostic or therapeutic tool…”
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Titration of 124 antibodies using CITE-Seq on human PBMCs by Nettersheim, Felix Sebastian, Armstrong, Sujit Silas, Durant, Christopher, Blanco-Dominguez, Rafael, Roy, Payel, Orecchioni, Marco, Suryawanshi, Vasantika, Ley, Klaus

“…Single-cell RNA-sequencing (scRNA-Seq) is widely used to characterize immune cell populations. However, mRNA levels correlate poorly with expression of surface…”
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Few‐Layer Graphene Kills Selectively Tumor Cells from Myelomonocytic Leukemia Patients by Russier, Julie, León, Verónica, Orecchioni, Marco, Hirata, Eri, Virdis, Patrizia, Fozza, Claudio, Sgarrella, Francesco, Cuniberti, Gianaurelio, Prato, Maurizio, Vázquez, Ester, Bianco, Alberto, Delogu, Lucia G.

“…In the cure of cancer, a major cause of today's mortality, chemotherapy is the most common treatment, though serious frequent challenges are encountered by…”
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Impact of carbon nanotubes and graphene on immune cells by Orecchioni, Marco, Bedognetti, Davide, Sgarrella, Francesco, Marincola, Francesco M, Bianco, Alberto, Delogu, Lucia Gemma

“…It has been recently proposed that nanomaterials, alone or in concert with their specific biomolecular conjugates, can be used to directly modulate the immune…”
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High-Affinity Bent β2-Integrin Molecules in Arresting Neutrophils Face Each Other through Binding to ICAMs In cis by Fan, Zhichao, Kiosses, William Bill, Sun, Hao, Orecchioni, Marco, Ghosheh, Yanal, Zajonc, Dirk M., Arnaout, M. Amin, Gutierrez, Edgar, Groisman, Alex, Ginsberg, Mark H., Ley, Klaus

“…Leukocyte adhesion requires β2-integrin activation. Resting integrins exist in a bent-closed conformation—i.e., not extended (E−) and not high affinity…”
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Immune cell impact of three differently coated lipid nanocapsules: pluronic, chitosan and polyethylene glycol by Farace, Cristiano, Sánchez-Moreno, Paola, Orecchioni, Marco, Manetti, Roberto, Sgarrella, Francesco, Asara, Yolande, Peula-García, José M., Marchal, Juan A., Madeddu, Roberto, Delogu, Lucia G.

“…Lipid nanocapsules (NCs) represent promising tools in clinical practice for diagnosis and therapy applications. However, the NC appropriate functionalization…”
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Signaling Response to Transient Redox Stress in Human Isolated T Cells: Molecular Sensor Role of Syk Kinase and Functional Involvement of IL2 Receptor and L-Selectine by Secchi, Christian, Orecchioni, Marco, Carta, Marissa, Galimi, Francesco, Turrini, Francesco, Pantaleo, Antonella

“…Reactive oxygen species (ROS) are central effectors of inflammation and play a key role in cell signaling. Previous reports have described an association…”
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Molecular and Genomic Impact of Large and Small Lateral Dimension Graphene Oxide Sheets on Human Immune Cells from Healthy Donors by Orecchioni, Marco, Jasim, Dhifaf A., Pescatori, Mario, Manetti, Roberto, Fozza, Claudio, Sgarrella, Francesco, Bedognetti, Davide, Bianco, Alberto, Kostarelos, Kostas, Delogu, Lucia Gemma

“…Graphene oxide (GO) is attracting great interest in biomedical sciences. The impact of GO on immune cells is one fundamental area of study that is often…”
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Corrigendum: Macrophage Polarization: Different Gene Signatures in M1(LPS+) vs. Classically and M2(LPS-) vs. Alternatively Activated Macrophages by Orecchioni, Marco, Ghosheh, Yanal, Pramod, Akula Bala, Ley, Klaus

“…[This corrects the article DOI: 10.3389/fimmu.2019.01084.]…”
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Editorial: Role of innate and adaptive immune cells in the metabolic syndrome by Roy, Payel, Winkels, Holger, Orecchioni, Marco, Quesada-Masachs, Estefania, Riffelmacher, Thomas

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Autoimmune Regulator (AIRE) Deficiency Does Not Affect Atherosclerosis and CD4 T Cell Immune Tolerance to Apolipoprotein B by Nettersheim, Felix Sebastian, Braumann, Simon, Kobiyama, Kouji, Orecchioni, Marco, Vassallo, Melanie, Miller, Jacqueline, Ali, Amal, Roy, Payel, Saigusa, Ryosuke, Wolf, Dennis, Ley, Klaus, Winkels, Holger

“…Atherosclerosis is a chronic, lipid-driven disease of medium sized arteries which causes myocardial infarction and stroke. Recently, an adaptive immune…”
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Bioinspired Scaffold Action Under the Extreme Physiological Conditions of Simulated Space Flights: Osteogenesis Enhancing Under Microgravity by Avitabile, Elisabetta, Fusco, Laura, Minardi, Silvia, Orecchioni, Marco, Zavan, Barbara, Yilmazer, Acelya, Rauner, Martina, Pippia, Proto, Tasciotti, Ennio, Delogu, Lucia Gemma

“…Prolonged exposure to microgravity (MG) during long-duration space flights is known to induce severe dysregulation of osteoblast functions connected to a…”
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How the immune system shapes atherosclerosis: roles of innate and adaptive immunity by Roy, Payel, Orecchioni, Marco, Ley, Klaus

“…Atherosclerosis is the root cause of many cardiovascular diseases. Extensive research in preclinical models and emerging evidence in humans have established…”
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Few‐Layer Graphene Kills Selectively Tumor Cells from Myelomonocytic Leukemia Patients by Russier, Julie, León, Verónica, Orecchioni, Marco, Hirata, Eri, Virdis, Patrizia, Fozza, Claudio, Sgarrella, Francesco, Cuniberti, Gianaurelio, Prato, Maurizio, Vázquez, Ester, Bianco, Alberto, Delogu, Lucia G.

“…In the cure of cancer, a major cause of today's mortality, chemotherapy is the most common treatment, though serious frequent challenges are encountered by…”
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Graphene and the immune system: Challenges and potentiality by Orecchioni, Marco, Ménard-Moyon, Cécilia, Delogu, Lucia Gemma, Bianco, Alberto

“…In the growing area of nanomedicine, graphene-based materials (GBMs) are some of the most recent explored nanomaterials. For the majority of GBM applications…”
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Impact of the surface functionalization on nanodiamond biocompatibility: a comprehensive view on human blood immune cells by Fusco, Laura, Avitabile, Elisabetta, Armuzza, Valentina, Orecchioni, Marco, Istif, Akcan, Bedognetti, Davide, Da Ros, Tatiana, Delogu, Lucia Gemma

“…Nanodiamonds (NDs) represent a class of carbon nanostructures widely investigated as promising biomedical nanotools. The possible immune system reactions…”
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Olfactory receptor 2 in vascular macrophages drives atherosclerosis by NLRP3-dependent IL-1 production by Orecchioni, Marco, Kobiyama, Kouji, Winkels, Holger, Ghosheh, Yanal, McArdle, Sara, Mikulski, Zbigniew, Kiosses, William B, Fan, Zhichao, Wen, Lai, Jung, Yunmin, Roy, Payel, Ali, Amal J, Miyamoto, Yukiko, Mangan, Matthew, Makings, Jeffrey, Wang, Zhihao, Denn, Angela, Vallejo, Jenifer, Owens, Michaela, Durant, Christopher P, Braumann, Simon, Mader, Navid, Li, Lin, Matsunami, Hiroaki, Eckmann, Lars, Latz, Eicke, Wang, Zeneng, Hazen, Stanley L, Ley, Klaus

“…Atherosclerosis is an inflammatory disease of the artery walls and involves immune cells such as macrophages. Olfactory receptors (OLFRs) are G protein–coupled…”
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