Search Results - "Ordi Ros, Josep"
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Molecular mechanisms mediated by human endogenous retroviruses (HERVs) in autoimmunity
Published in Reviews in medical virology (01-09-2009)“…Eight per cent of the human genome is derived from the integration of retroviral sequences that were incorporated in our DNA more than 25 million years ago…”
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2
Transcript overexpression of the MBD2 and MBD4 genes in CD4+ T cells from systemic lupus erythematosus patients
Published in Journal of leukocyte biology (01-06-2007)“…Global DNA hypomethylation in CD4+ T cells has been detected in systemic lupus erythematosus (SLE), and it seems to be linked to its pathogenesis. We…”
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3
miR-29c in urinary exosomes as predictor of early renal fibrosis in lupus nephritis
Published in Nephrology, dialysis, transplantation (01-09-2015)“…Despite overall improvement in prognosis, 10-30% of patients with lupus nephritis (LN) will develop end-stage renal disease. To date, renal biopsy is still the…”
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The Urinary Exosomal miRNA Expression Profile is Predictive of Clinical Response in Lupus Nephritis
Published in International journal of molecular sciences (18-02-2020)“…Data on exosomal-derived urinary miRNAs have identified several miRNAs associated with disease activity and fibrosis formation, but studies on prognosis are…”
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An Exosomal Urinary miRNA Signature for Early Diagnosis of Renal Fibrosis in Lupus Nephritis
Published in Cells (Basel, Switzerland) (25-07-2019)“…For lupus nephritis (LN) management, it is very important to detect fibrosis at an early stage. Urinary exosomal miRNAs profiling can be used as a potential…”
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Urinary Neuropilin-1: A Predictive Biomarker for Renal Outcome in Lupus Nephritis
Published in International journal of molecular sciences (17-09-2019)“…At present, Lupus Nephritis (LN) is still awaiting a biomarker to better monitor disease activity, guide clinical treatment, and predict a patient's long-term…”
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DNA Methylation and Systemic Lupus Erythematosus
Published in Annals of the New York Academy of Sciences (01-06-2007)“…: Several studies have indicated the importance of DNA hypomethylation in the etiology of systemic lupus erythematosus (SLE). Different enzymes linked to the…”
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Transcript levels of DNA methyltransferases DNMT1, DNMT3A and DNMT3B in CD4⁺ T cells from patients with systemic lupus erythematosus
Published in Immunology (01-07-2008)“…Global DNA hypomethylation in CD4⁺ T cells has been detected in systemic lupus erythematosus (SLE) and it seems to be linked to its pathogenesis. We…”
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9
Associations between the expression of epigenetically regulated genes and the expression of DNMTs and MBDs in systemic lupus erythematosus
Published in PloS one (21-09-2012)“…We determined the expression of ITGAL, PRF1, KIR2DL4, CD70, and CD40LG in patients with SLE and performed correlations with the global DNA methylation status…”
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Genetic risk factors of thrombosis in the antiphospholipid syndrome
Published in British journal of haematology (01-11-2009)“…Summary The possibility of a genetic predisposition to develop antiphospholipid syndrome (APS) and to produce anticardiolipin antibodies and lupus…”
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Further evidence of subphenotype association with systemic lupus erythematosus susceptibility loci: a European cases only study
Published in PloS one (26-09-2012)“…Systemic Lupus Erythematosus (SLE) shows a spectrum of clinical manifestations that complicate its diagnosis, treatment and research. This variability is…”
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Antiphosphatidylethanolamine antibodies contribute to the diagnosis of antiphospholipid syndrome in patients with systemic lupus erythematosus
Published in Scandinavian journal of rheumatology (01-01-2001)“…Objective: To evaluate the correlation between antiphosphatidylethanolamine antibodies (aPE) and some antiphospholipid antibodies (aPL)-related clinical…”
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Association of systemic lupus erythematosus clinical features with European population genetic substructure
Published in PloS one (14-12-2011)“…Systemic Lupus Erythematosus (SLE) is an autoimmune disease with a very varied spectrum of clinical manifestations that could be partly determined by genetic…”
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Changes in Lipid Profile Between Flare and Remission of Patients with Systemic Lupus Erythematosus: A Prospective Study
Published in Journal of rheumatology (01-08-2009)“…Objective. To determine the lipid profile of patients with systemic lupus erythematosus (SLE) according to the disease activity, and to calculate the…”
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Serum Levels of Soluble CD40 Ligand at Flare and at Remission in Patients with Systemic Lupus Erythematosus
Published in Journal of rheumatology (01-05-2009)“…Objective. To perform a prospective evaluation of soluble CD40 ligand (sCD40L) levels according to the activity of systemic lupus erythematosus (SLE). Methods…”
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Anticardiolipin antibodies in patients with chronic hepatitis C virus infection: characterization in relation to antiphospholipid syndrome
Published in Clinical and diagnostic laboratory immunology (01-03-2000)“…The antiphospholipid syndrome (APS) is usually defined by the association of clinical manifestations that comprise venous and/or arterial thrombosis, recurrent…”
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Rivaroxaban Versus Vitamin K Antagonist in Antiphospholipid Syndrome: A Randomized Noninferiority Trial
Published in Annals of internal medicine (19-11-2019)“…The potential role of new oral anticoagulants in antiphospholipid antibody syndrome (APS) remains uncertain. To determine whether rivaroxaban is noninferior to…”
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Mutations of activin-receptor-like kinase 1 (ALK-1) are not found in patients with pulmonary hypertension and underlying connective tissue disease
Published in Clinical rheumatology (01-06-2007)“…Pulmonary arterial hypertension is a recognized clinical component of systemic autoimmune diseases, especially systemic sclerosis. Mutations in the bone…”
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IgA anticardiolipin antibodies--relation with other antiphospholipid antibodies and clinical significance
Published in Thrombosis and haemostasis (01-02-1998)“…To evaluate the usefulness of IgA antiphospholipid antibodies as markers of thrombosis and/or antiphospholipid antibody syndrome. A cross-sectional study…”
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MicroRNA Expression Profiling Identifies miR-31 and miR-485-3p as Regulators in the Pathogenesis of Discoid Cutaneous Lupus
Published in Journal of investigative dermatology (01-01-2019)“…Cutaneous lupus erythematosus is a common and disfiguring manifestation in systemic lupus erythematosus. Subacute cutaneous lupus erythematosus and discoid…”
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