Search Results - "Ordóñez, Flor A."
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1
Bone Disease in CKD in Children
Published in Calcified tissue international (01-04-2021)“…This manuscript discusses mineral and bone disorders of chronic kidney disease (MBD-CKD) in pediatric patients with special emphasis on the underlying…”
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2
Rapamycin induces growth retardation by disrupting angiogenesis in the growth plate
Published in Kidney international (01-09-2010)“…Rapamycin, a potent immunosuppressant used in renal transplantation, has been reported to impair longitudinal growth in experimental studies. Rapamycin is both…”
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3
Tubulointerstitial nephritis and uveitis syndrome and SARS-CoV-2 infection in an adolescent: just a coincidence in time?
Published in Pediatric nephrology (Berlin, West) (01-12-2023)“…Background Despite recent well-established kidney tropism of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), usually presenting as acute kidney…”
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4
Clinical and laboratory approaches in the diagnosis of renal tubular acidosis
Published in Pediatric nephrology (Berlin, West) (01-12-2015)“…In the absence of a gastrointestinal origin, a maintained hyperchloremic metabolic acidosis must raise the diagnostic suspicion of renal tubular acidosis…”
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5
Chronic kidney disease induced by adenine: a suitable model of growth retardation in uremia
Published in American journal of physiology. Renal physiology (01-07-2015)“…Growth retardation is a major manifestation of chronic kidney disease (CKD) in pediatric patients. The involvement of the various pathogenic factors is…”
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6
Hypophosphatemia and growth
Published in Pediatric nephrology (Berlin, West) (01-04-2013)“…Over the last decade the discovery of fibroblast growth factor 23 (FGF23) and the progressive and ongoing clarification of its role in phosphate and mineral…”
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7
Molecular Mechanisms of Proteinuria in Minimal Change Disease
Published in Frontiers in medicine (23-12-2021)“…Minimal change disease (MCD) is the most common type of idiopathic nephrotic syndrome in childhood and represents about 15% cases in adults. It is…”
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8
β1-Integrin blockade prevents podocyte injury in experimental models of minimal change disease
Published in Nefrología (01-01-2024)“…Activation of the focal adhesion kinase (FAK) in podocytes is involved in the pathogenesis of minimal change disease (MCD), but the pathway leading to its…”
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9
Growth hormone improves growth retardation induced by rapamycin without blocking its antiproliferative and antiangiogenic effects on rat growth plate
Published in PloS one (06-04-2012)“…Rapamycin, an immunosuppressant agent used in renal transplantation with antitumoral properties, has been reported to impair longitudinal growth in young…”
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10
Minimal Change Disease Is Associated With Endothelial Glycocalyx Degradation and Endothelial Activation
Published in Kidney international reports (01-04-2022)“…Minimal change disease (MCD) is considered a podocyte disorder triggered by unknown circulating factors. Here, we hypothesized that the endothelial cell (EC)…”
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11
Outcome of primary tubular tubulopathies diagnosed in pediatric age
Published in Nefrología (01-03-2021)“…Primary tubulopathies are rare and usually present at pediatric age. Recent advances in genetic diagnosis and treatment have changed its natural history. This…”
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12
Effects of growth hormone treatment on growth plate, bone, and mineral metabolism of young rats with uremia induced by adenine
Published in Pediatric research (01-07-2017)“…Background In a model of growth retardation secondary to chronic kidney disease (CKD) induced by adenine, this study explores the effects of growth hormone…”
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13
Rapamycin retards growth and causes marked alterations in the growth plate of young rats
Published in Pediatric nephrology (Berlin, West) (01-07-2007)“…Rapamycin is a potent immunosuppressant with antitumoral properties widely used in the field of renal transplantation. To test the hypothesis that the…”
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14
Resistance to growth hormone and insulin-like growth factor-I in acidotic rats
Published in Pediatric nephrology (Berlin, West) (01-08-2000)“…Growth impairment induced by chronic metabolic acidosis is associated with an abnormal growth hormone (GH)/insulin-like growth factor-I (IGF-I) axis. To…”
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15
Alterations of growth plate and abnormal insulin-like growth factor I metabolism in growth-retarded hypokalemic rats: effect of growth hormone treatment
Published in American journal of physiology. Renal physiology (01-09-2009)“…Hypokalemic tubular disorders may lead to growth retardation which is resistant to growth hormone (GH) treatment. The mechanism of these alterations is…”
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16
Distal RTA with nerve deafness: clinical spectrum and mutational analysis in five children
Published in Pediatric nephrology (Berlin, West) (01-06-2007)“…Distal renal tubular acidosis (RTA) with nerve deafness is caused by mutations in the ATP6V1B1 gene causing defective function of the H+ -ATPase proton pump…”
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17
La complejidad clínica del gen PKHD1: de la letalidad perinatal al diagnóstico casual en etapas pediátricas tardías
Published in Anales de pediatría (Barcelona, Spain : 2003) (01-06-2024)Get full text
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18
Outcome of primary tubular tubulopathies diagnosed in pediatric age
Published in Nefrología (01-03-2021)“…BACKGROUND AND OBJECTIVEPrimary tubulopathies are rare and usually present at pediatric age. Recent advances in genetic diagnosis and treatment have changed…”
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19
Evolución de tubulopatías renales primarias diagnosticadas en edad pediátrica
Published in Nefrología (01-03-2021)“…Las tubulopatías primarias son raras y se presentan habitualmente en la edad pediátrica. Avances recientes en diagnóstico genético y tratamiento han cambiado…”
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20
Hipertensión arterial en el lactante. Un reto diagnóstico en pediatría
Published in Anales de pediatría (Barcelona, Spain : 2003) (01-02-2021)“…La prevalencia de la hipertensión arterial ha aumentado considerablemente en la edad pediátrica como consecuencia principal de su detección en niños mayores y…”
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