Search Results - "Ord, James"
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Ionic Stress Prompts Premature Hatching of Zebrafish (Danio rerio) Embryos
Published in Fishes (01-03-2019)“…Ionic homeostasis is an essential component of functioning cells, and ionic stress imposed by excessive salinity can disrupt cellular and physiological…”
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Journal Article -
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Zeta Potential of Extracellular Vesicles: Toward Understanding the Attributes that Determine Colloidal Stability
Published in ACS omega (14-07-2020)“…Extracellular vesicles (EVs), including exosomes and microvesicles (<200 nm), play a vital role in intercellular communication and carry a net negative surface…”
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Trophoblast derived extracellular vesicles specifically alter the transcriptome of endometrial cells and may constitute a critical component of embryo-maternal communication
Published in Reproductive biology and endocrinology (21-07-2021)“…The period of time when the embryo and the endometrium undergo significant morphological alterations to facilitate a successful implantation-known as "window…”
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Bovine Follicular Fluid and Extracellular Vesicles Derived from Follicular Fluid Alter the Bovine Oviductal Epithelial Cells Transcriptome
Published in International journal of molecular sciences (28-07-2020)“…While follicular fluid (FF) is well known to provide an optimal environment for oogenesis, its functional roles following its release into the oviduct during…”
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Maternal Chronic Ethanol Exposure Decreases Stress Responses in Zebrafish Offspring
Published in Biomolecules (Basel, Switzerland) (19-08-2022)“…In humans, prenatal alcohol exposure can cause serious health issues in children, known collectively as Foetal Alcohol Spectrum Disorders (FASD). Despite the…”
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Optimal detection protocol of Tetracapsuloides bryosalmonae by environmental DNA: A comparison of qPCR and ddPCR approaches
Published in Environmental DNA (Hoboken, N.J.) (01-01-2024)“…Investigation of environmental DNA (eDNA) is increasingly used to precisely and non‐invasively detect and monitor pathogens. Among these, Tetracapsuloides…”
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Journal Article -
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Paternal effects in a wild‐type zebrafish implicate a role of sperm‐derived small RNAs
Published in Molecular ecology (01-07-2020)“…While the importance of maternal effects has long been appreciated, a growing body of evidence now points to the paternal environment having an important…”
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Journal Article -
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High Nucleotide Diversity Accompanies Differential DNA Methylation in Naturally Diverging Populations
Published in Molecular biology and evolution (04-04-2023)“…Abstract Epigenetic mechanisms such as DNA methylation (DNAme) are thought to comprise an invaluable adaptive toolkit in the early stages of local adaptation,…”
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Brief exposures to conspecific-derived alarm substance are sufficient to induce paternal intergenerational effects in zebrafish
Published in Environmental biology of fishes (01-06-2022)“…Paternal intergenerational effects, whereby the father’s environment influences the phenotype of the offspring via molecular (e.g. epigenetic) changes to the…”
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Time-critical influences of gestational diet in a seahorse model of male pregnancy
Published in Journal of experimental biology (07-02-2020)“…Sex role reversal is not uncommon in the animal kingdom but is taken to the extreme by the Syngnathidae, in which male pregnancy is one of the most astonishing…”
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Oviduct as a sensor of embryo quality: deciphering the extracellular vesicle (EV)-mediated embryo-maternal dialogue
Published in Journal of molecular medicine (Berlin, Germany) (01-05-2021)“…Embryo-derived extracellular vesicles (EVs) may play a role in mediating the embryo-maternal dialogue at the oviduct, potentially carrying signals reflecting…”
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Journal Article -
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Parental stress and its effects on the offspring of guppies (Poecilia reticulata) and zebrafish (Danio rerio)
Published 01-01-2019“…Parental stress, either in the context of pregnancy or pre-conception, is increasingly recognised as a contributing factor to offspring disease risk. While the…”
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Dissertation -
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Premature birth stunts early growth and is a possible driver of stress‐induced maternal effects in the guppy Poecilia reticulata
Published in Journal of fish biology (01-02-2020)“…We tested the effects of gestational stress, principally in the form of alarm cue extracted from the skin of conspecifics, on reproduction in female guppies…”
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Spermatozoa, acts as an external cue and alters the cargo and production of the extracellular vesicles derived from oviductal epithelial cells in vitro
Published in Journal of cell communication and signaling (01-09-2023)“…The oviduct provides optimum physiological and biochemical milieu essential for successful fertilization, early embryo development and facilitates functional…”
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Long-Term Effects of the Periconception Period on Embryo Epigenetic Profile and Phenotype: The Role of Stress and How This Effect Is Mediated
Published in Advances in experimental medicine and biology (01-01-2017)“…Stress represents an unavoidable aspect of human life, and pathologies associated with dysregulation of stress mechanisms - particularly psychiatric disorders…”
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Journal Article -
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Spermatozoa induce transcriptomic alterations in bovine oviductal epithelial cells prior to initial contact
Published in Journal of cell communication and signaling (01-12-2020)“…The capability of spermatozoa to directly influence maternal gene expression is already established. Indeed, some of the changes induced by spermatozoa may…”
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Legal and Moral Constraints on Low-Intensity Conflict
Published in American journal of international law (01-01-1997)“…"Legal and Moral Constraints on Low-Intensity Conflict" edited by Alberto R. Coll, James C. Ord, and Stephen A. Rose is reviewed…”
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Book Review