Search Results - "Orban, C."

Metabolic response to the stress of critical illness by Preiser, J.-C., Ichai, C., Orban, J.-C., Groeneveld, A.B.J.

“…The metabolic response to stress is part of the adaptive response to survive critical illness. Several mechanisms are well preserved during evolution,…”
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A higher-than-predicted measurement of iron opacity at solar interior temperatures by Bailey, J. E., Nagayama, T., Loisel, G. P., Rochau, G. A., Blancard, C., Colgan, J., Cosse, Ph, Faussurier, G., Fontes, C. J., Gilleron, F., Golovkin, I., Hansen, S. B., Iglesias, C. A., Kilcrease, D. P., MacFarlane, J. J., Mancini, R. C., Nahar, S. N., Orban, C., Pain, J.-C., Pradhan, A. K., Sherrill, M., Wilson, B. G.

“…Laboratory measurements of iron opacity made under conditions similar to those inside the Sun reveal much higher opacity than predicted, helping to resolve…”
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Ectopic germline recombination activity of the widely used Foxp3‐YFP‐Cre mouse: a case report by Wu, Dan, Huang, Qing, Orban, Paul C., Levings, Megan K.

“…Summary Regulatory T (Treg) cell‐specific deletion of a gene of interest is a procedure widely used to study mechanisms controlling Treg development,…”
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Tregs with an MHC class II peptide-specific chimeric antigen receptor prevent autoimmune diabetes in mice by Spanier, Justin A, Fung, Vivian, Wardell, Christine M, Alkhatib, Mohannad H, Chen, Yixin, Swanson, Linnea A, Dwyer, Alexander J, Weno, Matthew E, Silva, Nubia, Mitchell, Jason S, Orban, Paul C, Mojibian, Majid, Verchere, C Bruce, Fife, Brian T, Levings, Megan K

“…Adoptive immunotherapy with Tregs is a promising approach for preventing or treating type 1 diabetes. Islet antigen-specific Tregs have more potent therapeutic…”
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Systematic Study of L-Shell Opacity at Stellar Interior Temperatures by Nagayama, T, Bailey, J E, Loisel, G P, Dunham, G S, Rochau, G A, Blancard, C, Colgan, J, Cossé, Ph, Faussurier, G, Fontes, C J, Gilleron, F, Hansen, S B, Iglesias, C A, Golovkin, I E, Kilcrease, D P, MacFarlane, J J, Mancini, R C, More, R M, Orban, C, Pain, J-C, Sherrill, M E, Wilson, B G

“…The first systematic study of opacity dependence on atomic number at stellar interior temperatures is used to evaluate discrepancies between measured and…”
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Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety by Tronche, François, Kellendonk, Christoph, Kretz, Oliver, Gass, Peter, Anlag, Katrin, Orban, Paul C, Bock, Rudolf, Klein, Rüdiger, Schütz, Günther

“…The glucocorticoid receptor (Gr, encoded by the gene Grl1) controls transcription of target genes both directly by interaction with DNA regulatory elements and…”
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Role of Brain Insulin Receptor in Control of Body Weight and Reproduction by Brüning, Jens C., Gautam, Dinesh, Burks, Deborah J., Gillette, Jennifer, Schubert, Markus, Orban, Paul C., Klein, Rüdiger, Krone, Wilhelm, Müller-Wieland, Dirk, Kahn, C. Ronald

“…Insulin receptors (IRs) and insulin signaling proteins are widely distributed throughout the central nervous system (CNS). To study the physiological role of…”
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Computational Thinking in Introductory Physics by Orban, C. M, Teeling-Smith, R. M

“…Computational thinking" (CT) is still a relatively new term in the lexicon of learning objectives and science standards. The term was popularized in an essay…”
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The indole motif is essential for the antitrypanosomal activity of N5-substituted paullones by Ihnatenko, Irina, Müller, Marco J, Orban, Oliver C F, Lindhof, Jens C, Benítez, Diego, Ortíz, Cecilia, Dibello, Estefanía, Seidl, Leonardo L, Comini, Marcelo A, Kunick, Conrad

“…Severe infections with potentially fatal outcomes are caused by parasites from the genera Trypanosoma and Leishmania (class Kinetoplastea). The diseases affect…”
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Using Virtual Reality in Electrostatics Instruction: The Impact of Training by Porter, C. D, Smith, J. R. H, Stagar, E. M, Simmons, A, Nieberding, M, Orban, C. M, Brown, J, Ayers, A

“…Recent years have seen a resurgence of interest in using virtual reality (VR) technology to benefit instruction, especially in physics and related subjects. As…”
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Prevention of murine autoimmune diabetes by CCL22-mediated Treg recruitment to the pancreatic islets by Montane, Joel, Bischoff, Loraine, Soukhatcheva, Galina, Dai, Derek L, Hardenberg, Gijs, Levings, Megan K, Orban, Paul C, Kieffer, Timothy J, Tan, Rusung, Verchere, C Bruce

“…Type 1 diabetes is characterized by destruction of insulin-producing β cells in the pancreatic islets by effector T cells. Tregs, defined by the markers CD4…”
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Cellular mechanisms of CCL22-mediated attenuation of autoimmune diabetes by Bischoff, Loraine, Alvarez, Sigrid, Dai, Derek L, Soukhatcheva, Galina, Orban, Paul C, Verchere, C Bruce

“…Autoimmune destruction of insulin-producing β cells in type 1 diabetes and islet transplantation involves a variety of immune pathways but is primarily…”
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An INSULIN and IAPP dual reporter enables tracking of functional maturation of stem cell-derived insulin producing cells by Bayly, Carmen L., Dai, Xiao-Qing, Nian, Cuilan, Orban, Paul C., Verchere, C. Bruce, MacDonald, Patrick E., Lynn, Francis C.

“…Human embryonic stem cell (hESC; SC)-derived pancreatic β cells can be used to study diabetes pathologies and develop cell replacement therapies. Although…”
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Neonatal T Helper 17 Responses Are Skewed Towards an Immunoregulatory Interleukin-22 Phenotype by Razzaghian, Hamid R, Sharafian, Zohreh, Sharma, Ashish A, Boyce, Guilaine K, Lee, Kelsey, Da Silva, Rachel, Orban, Paul C, Sekaly, Rafick-Pierre, Ross, Colin J, Lavoie, Pascal M

“…Newborns are frequently affected by mucocutaneous candidiasis. Th17 cells essentially limit mucosal invasion by commensal spp. Here, we sought to understand…”
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Palmitoylation of huntingtin by HIP14is essential for its trafficking and function by Yanai, Anat, Huang, Kun, Kang, Rujun, Singaraja, Roshni R, Arstikaitis, Pamela, Gan, Lu, Orban, Paul C, Mullard, Asher, Cowan, Catherine M, Raymond, Lynn A, Drisdel, Renaldo C, Green, William N, Ravikumar, Brinda, Rubinsztein, David C, El-Husseini, Alaa, Hayden, Michael R

“…Post-translational modification by the lipid palmitate is crucial for the correct targeting and function of many proteins. Here we show that huntingtin (htt)…”
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Ras-Guanine Nucleotide-Releasing Factor 1 (Ras-GRF1) Controls Activation of Extracellular Signal-Regulated Kinase (ERK) Signaling in the Striatum and Long-Term Behavioral Responses to Cocaine by Fasano, Stefania, D'Antoni, Angela, Orban, Paul C, Valjent, Emmanuel, Putignano, Elena, Vara, Hugo, Pizzorusso, Tommaso, Giustetto, Maurizio, Yoon, Bongjune, Soloway, Paul, Maldonado, Rafael, Caboche, Jocelyne, Brambilla, Riccardo

“…Background Ras-extracellular signal-regulated kinase (Ras-ERK) signaling is central to the molecular machinery underlying cognitive functions. In the striatum,…”
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Islet amyloid polypeptide does not suppress pancreatic cancer by Taylor, Austin J., Panzhinskiy, Evgeniy, Orban, Paul C., Lynn, Francis C., Schaeffer, David F., Johnson, James D., Kopp, Janel L., Verchere, C. Bruce

“…Pancreatic cancer risk is elevated approximately two-fold in type 1 and type 2 diabetes. Islet amyloid polypeptide (IAPP) is an abundant beta-cell peptide…”
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A hybrid approach for using programming exercises in introductory physics by Orban, C. M., Teeling-Smith, R. M., Smith, J. R. H., Porter, C. D.

“…Incorporating computer programming exercises into introductory physics is a delicate task that involves a number of choices that may have an effect on student…”
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The Use of an Inulin-Type Prebiotic in Non-Alcoholic Steatohepatitis by Iliescu, L, Toma, L, Minzala, G, Tanase, A, Orban, C

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Proximal junction and transitional mechanics and effect of a novel tether pedicle screw in long-segment spinal instrumentation by Gmeiner, R., Koller, H., Lener, S., Orban, C., Abramovic, A., Konschake, M., SchmÖLz, W., ThomÉ, C., Hartmann, S.

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