Search Results - "Orallo, F"
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Comparative studies of the antioxidant effects of cis- and trans-resveratrol
Published in Current medicinal chemistry (2006)“…Resveratrol (3,4',5-trihydroxystilbene, RESV) is a natural phenolic compound that exists as cis and trans isomers [c-RESV or (Z)-RESV and t-RESV or (E)-RESV,…”
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2
Short‐term or long‐term treatments with a phosphodiesterase‐4 (PDE4) inhibitor result in opposing agonist‐induced Ca2+ responses in endothelial cells
Published in British journal of pharmacology (01-05-2008)“…Background and purpose: We previously reported that agonist‐induced rises in cytoplasmic Ca2+ concentration ([Ca2+]i) in human umbilical vein endothelial cells…”
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3
Short-term or long-term treatments with a phosphodiesterase-4 (PDE4) inhibitor result in opposing agonist-induced Ca(2+) responses in endothelial cells
Published in British journal of pharmacology (01-05-2008)“…We previously reported that agonist-induced rises in cytoplasmic Ca(2+) concentration ([Ca(2+)](i)) in human umbilical vein endothelial cells (HUVEC) were…”
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4
Effect of cis-resveratrol on genes involved in nuclear factor kappa B signaling
Published in International immunopharmacology (01-02-2005)“…This study investigated for the first time the effects of the cis isomer of RESV ( c-RESV), a polyphenol present in red wine, on an array of genes whose…”
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Synthesis of new 3-aryl-4,5-dihydropyrazole-1-carbothioamide derivatives. An investigation on their ability to inhibit monoamine oxidase
Published in European journal of medicinal chemistry (01-10-2010)“…Some differently substituted 3-aryl-4,5-dihydropyrazoles-1-carbothioamides have been synthesised with the aim to investigate their monoamine oxidase inhibitory…”
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6
Resveratrol modulates innate and inflammatory responses in fish leucocytes
Published in Veterinary immunology and immunopathology (15-11-2008)“…Resveratrol (RESV; trans-3,5,4’-trihydroxystilbene), a phytoalexin that is produced by some plants, among other effects has well-known antioxidant,…”
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7
Effect of (−)-epigallocatechin-3-gallate on respiratory burst of rat macrophages
Published in International immunopharmacology (01-05-2002)“…The toxic effects derived from overproduction of oxygen radicals [reactive oxygen species (ROS)] by immune cells can be partially abolished by the antioxidant…”
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Resveratrol promotes an inhibitory effect on the turbot scuticociliate parasite Philasterides dicentrarchi by mechanisms related to cellular detoxification
Published in Veterinary parasitology (12-05-2009)“…The mechanisms involved in antiparasitic activity of the natural nonflavonoid polyphenol resveratrol (RESV) on the turbot ( Psetta maxima) scuticoliate…”
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9
An Anacardiaceae preparation reduces the expression of inflammation-related genes in murine macrophages
Published in International immunopharmacology (01-08-2004)“…This study investigated the effects of an aqueous extract of the stem bark of Mangifera indica L. (Anacardiaceae; Vimang®), which contains a defined mixture of…”
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10
Resveratrol modulates rat macrophage functions
Published in International immunopharmacology (01-05-2002)“…This study investigated the effects of trans-resveratrol ( trans-3,4′,5-trihydroxystilbene, RESV), a natural polyphenol from grapes with known antioxidant…”
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Preliminary study of the vasorelaxant effects of (+)-nantenine, an alkaloid isolated from Platycapnos spicata, in rat aorta
Published in Planta medica (01-12-2001)“…In this work, the potential vasorelaxant activity of (+)-nantenine, an alkaloid isolated from Platycapnos spicata, was studied for the first time in rat aorta…”
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Preliminary study of the potential vasodilator effects on rat aorta of centaurein and centaureidin, two flavonoids from Centaurea corcubionensis
Published in Planta medica (01-03-1998)“…In this work, the potential vasorelaxant activity of centaurein and centaureidin, two flavonoids from Centaurea corcubionensis, were studied for the first time…”
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13
Inhibitory effects of cis- and trans-resveratrol on noradrenaline and 5-hydroxytryptamine uptake and on monoamine oxidase activity
Published in Biochemical and biophysical research communications (02-06-2006)“…This study investigated for the first time the potential effects of cis- and trans-resveratrol ( c-RESV and t-RESV) on noradrenaline (NA) and…”
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14
Design, synthesis, and vasorelaxant and platelet antiaggregatory activities of coumarin–resveratrol hybrids
Published in Bioorganic & medicinal chemistry letters (15-01-2006)“…We have synthesized the coumarin–resveratrol hybrid 4 and its dimethoxy derivative 3 by a very direct synthetic route involving a Pechmann procedure. Compound…”
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Effects of cis-resveratrol on inflammatory murine macrophages: antioxidant activity and down-regulation of inflammatory genes
Published in Journal of leukocyte biology (01-06-2004)“…This study investigated for the first time the effects of the cis isomer of resveratrol (c‐RESV) on the responses of inflammatory murine peritoneal…”
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Acute cardiovascular effects of (+)-nantenine, an alkaloid isolated from Platycapnos spicata, in anaesthetised normotensive rats
Published in Planta medica (01-02-2004)“…This is the first study of the in vivo potential activity of (+)-nantenine (a natural aporphinoid alkaloid) on the rat cardiovascular system. In anaesthetized…”
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In vitro effects of mangiferin on superoxide concentrations and expression of the inducible nitric oxide synthase, tumour necrosis factor-α and transforming growth factor-β genes
Published in Biochemical pharmacology (15-04-2003)“…This study investigated the effects of the natural polyphenol mangiferin (MA) on superoxide anion (O 2 −) production, xanthine oxidase (XO) activity, vascular…”
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The possible implication of trans-Resveratrol in the cardioprotective effects of long-term moderate wine consumption
Published in Molecular pharmacology (01-02-2002)“…trans-Resveratrol (t-RESV; 1-10 microM), a phenolic component of wines, had no effect on phenylephrine-(PE; 1 microM) and high KCl-(60 mM) induced contractions…”
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Effects of ATP on cultured smooth muscle cells from rat aorta
Published in British journal of pharmacology (01-03-1993)“…1 Membrane ionic currents provoked by externally applied ATP were studied by patch‐clamp techniques in cultured aortic smooth muscle cells of the rat. 2 Using…”
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Pharmacological effects of (+)-nantenine, an alkaloid isolated from Platycapnos spicata, in several rat isolated tissues
Published in Planta medica (01-02-2003)“…In this work, the potential activity of (+)-nantenine (a natural aporphin alkaloid) in several rat isolated tissues was studied. In rat isolated intact aorta,…”
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