Search Results - "Orädd, Fredrik"

Copper binding leads to increased dynamics in the regulatory N-terminal domain of full-length human copper transporter ATP7B by Orädd, Fredrik, Steffen, Jonas Hyld, Gourdon, Pontus, Andersson, Magnus

“…ATP7B is a human copper-transporting P 1B -type ATPase that is involved in copper homeostasis and resistance to platinum drugs in cancer cells. ATP7B consists…”
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Diverse roles of the metal binding domains and transport mechanism of copper transporting P-type ATPases by Guo, Zongxin, Orädd, Fredrik, Bågenholm, Viktoria, Grønberg, Christina, Ma, Jian Feng, Ott, Peter, Wang, Yong, Andersson, Magnus, Pedersen, Per Amstrup, Wang, Kaituo, Gourdon, Pontus

“…Copper transporting P-type (P 1B-1 -) ATPases are essential for cellular homeostasis. Nonetheless, the E1-E1P-E2P-E2 states mechanism of P 1B-1 -ATPases…”
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Tracking Membrane Protein Dynamics in Real Time by Orädd, Fredrik, Andersson, Magnus

“…Membrane proteins govern critical cellular processes and are central to human health and associated disease. Understanding of membrane protein function is…”
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Copper-dependent ATP7B N-terminal domain dynamics in two reaction-cycle intermediates by Orädd, Fredrik, Andersson, Magnus

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Simulation of Copper-Dependent Regulation Dynamics in ATP7B by Orädd, Fredrik, Andersson, Magnus

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Structural basis of ion uptake in copper-transporting P1B-type ATPases by Salustros, Nina, Grønberg, Christina, Abeyrathna, Nisansala S., Lyu, Pin, Orädd, Fredrik, Wang, Kaituo, Andersson, Magnus, Meloni, Gabriele, Gourdon, Pontus

“…Copper is essential for living cells, yet toxic at elevated concentrations. Class 1B P-type (P 1B -) ATPases are present in all kingdoms of life, facilitating…”
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Real-time structural characterization of protein response to a caged compound by fast detector readout and high-brilliance synchrotron radiation by Magkakis, Konstantinos, Orädd, Fredrik, Ahn, Byungnam, Da Silva, Vanessa, Appio, Roberto, Plivelic, Tomás S, Andersson, Magnus

“…Protein dynamics are essential to biological function, and methods to determine such structural rearrangements constitute a frontier in structural biology…”
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Dephosphorylation and ion binding in prokaryotic calcium transport by Prabudiansyah, Irfan, Orädd, Fredrik, Magkakis, Konstantinos, Pounot, Kevin, Levantino, Matteo, Andersson, Magnus

“…Calcium (Ca 2+ ) signaling is fundamental to cellular processes in both eukaryotic and prokaryotic organisms. While the mechanisms underlying eukaryotic Ca 2+…”
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Tracking the ATP-binding response in adenylate kinase in real time by Orädd, Fredrik, Ravishankar, Harsha, Goodman, Jack, Rogne, Per, Backman, Lars, Duelli, Annette, Nors Pedersen, Martin, Levantino, Matteo, Wulff, Michael, Wolf-Watz, Magnus, Andersson, Magnus

“…The biological function of proteins is critically dependent on dynamics inherent to the native structure. Such structural dynamics obey a predefined order and…”
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Tracking the structural dynamics of SERCA regulation in real time by Orädd, Fredrik, Magkakis, Konstantinos, Prabudiansyah, Irfan, Levantino, Matteo, Inaba, Kenji, Andersson, Magnus

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Structural basis of ion uptake in copper-transporting P 1B -type ATPases by Salustros, Nina, Grønberg, Christina, Abeyrathna, Nisansala S, Lyu, Pin, Orädd, Fredrik, Wang, Kaituo, Andersson, Magnus, Meloni, Gabriele, Gourdon, Pontus

“…Copper is essential for living cells, yet toxic at elevated concentrations. Class 1B P-type (P -) ATPases are present in all kingdoms of life, facilitating…”
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Tracking lipid-induced effects on membrane protein structure in real time by Oradd, Fredrik, Prabudiansyah, Irfan, Magkakis, Konstantinos, Andersson, Magnus

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Tracking domain closing in the adenylate kinase reaction by Orádd, Fredrik, Ravishankar, Harsha, Rogne, Per, Backman, Lars, Wulff, Michael, Levantino, Matteo, Wolf-Watz, Magnus, Andersson, Magnus

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