Search Results - "Opsenica, Dejan M"

4-Aminoquinoline-Based Adamantanes as Potential Anticholinesterase Agents in Symptomatic Treatment of Alzheimer's Disease by Komatović, Katarina, Matošević, Ana, Terzić-Jovanović, Nataša, Žunec, Suzana, Šegan, Sandra, Zlatović, Mario, Maraković, Nikola, Bosak, Anita, Opsenica, Dejan M

“…Considering that acetylcholinesterase (AChE) inhibition is the most important mode of action expected of a potential drug used for the treatment of symptoms of…”
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Structural aspects of 4-aminoquinolines as reversible inhibitors of human acetylcholinesterase and butyrylcholinesterase by Bosak, Anita, Opsenica, Dejan M., Šinko, Goran, Zlatar, Matija, Kovarik, Zrinka

“…Eight derivatives of 4-aminoquinolines differing in the substituents attached to the C(4)-amino group and C(7) were synthesised and tested as inhibitors of…”
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Evaluation of 4-aminoquinoline derivatives with an n-octylamino spacer as potential multi-targeting ligands for the treatment of Alzheimer's disease by Matošević, Ana, Opsenica, Dejan M., Spasić, Marta, Maraković, Nikola, Zandona, Antonio, Žunec, Suzana, Bartolić, Marija, Kovarik, Zrinka, Bosak, Anita

“…The most successful therapeutic strategy in the treatment of Alzheimer's disease (AD) is directed toward increasing levels of the neurotransmitter…”
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Long-Chain 4‑Aminoquinolines as Quorum Sensing Inhibitors in Serratia marcescens and Pseudomonas aeruginosa by Aleksić, Ivana, Šegan, Sandra, Andrić, Filip, Zlatović, Mario, Moric, Ivana, Opsenica, Dejan M, Senerovic, Lidija

“…Antibiotic resistance has become a serious global threat to public health; therefore, improved strategies and structurally novel antimicrobials are urgently…”
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N‑Benzyl Derivatives of Long-Chained 4‑Amino-7-chloro-quionolines as Inhibitors of Pyocyanin Production in Pseudomonas aeruginosa by Aleksic, Ivana, Jeremic, Jelena, Milivojevic, Dusan, Ilic-Tomic, Tatjana, Šegan, Sandra, Zlatović, Mario, Opsenica, Dejan M, Senerovic, Lidija

“…Pseudomonas aeruginosa is a leading cause of nosocomial infections that are becoming increasingly difficult to treat due to the occurrence of antibiotic…”
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New 9-aminoacridine derivatives as inhibitors of Botulinum neurotoxins and P. falciparum malaria by Tot Mikloš, Opsenica Dejan M., Mitrić Milena, Burnett James C., Gomba Laura, Bavari Sina, Šolaja Bogdan A.

“…Steroidal and adamantane aminoacridine derivatives were prepared and tested as both botulinum neurotoxin (BoNT) inhibitors and antimalarials. Steroid-bound…”
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Strong in Vitro Cytotoxic Potential of New Ruthenium–Cymene Complexes by Nikolić, Stefan, Opsenica, Dejan M, Filipović, Vuk, Dojčinović, Biljana, Aranđelović, Sandra, Radulović, Siniša, Grgurić-Šipka, Sanja

“…Two p-cymenerutheniumchlorido complexes with thiourea derivative of 7-chloroquinoline (C1) and pyridine-3-imidazole (C2) were synthesized starting from…”
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Second Generation Steroidal 4‑Aminoquinolines Are Potent, Dual-Target Inhibitors of the Botulinum Neurotoxin Serotype A Metalloprotease and P. falciparum Malaria by Videnović, Milica, Opsenica, Dejan M, Burnett, James C, Gomba, Laura, Nuss, Jonathan E, Selaković, Života, Konstantinović, Jelena, Krstić, Maja, Šegan, Sandra, Zlatović, Mario, Sciotti, Richard J, Bavari, Sina, Šolaja, Bogdan A

“…Significantly more potent second generation 4-amino-7-chloroquinoline (4,7-ACQ) based inhibitors of the botulinum neurotoxin serotype A (BoNT/A) light chain…”
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Antimalarial peroxides by Opsenica Dejan M., Šolaja Bogdan A.

“…The problem of endemic malaria continues unabated globally. Malaria affects 40 % of the global population, causing an estimated annual mortality of 1.5-2.7…”
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NaY Zeolite: A Useful Catalyst for Nitrile Hydrolysis by Milić, Dragana, Opsenica, Dejan, Adnađević, Borivoje, Šolaja, Bogdan

“…The NaY zeolite catalysed hydrolysis of nitriles to primary amides is reported. It is found that aryl nitriles with strong electron-withdrawing substituents…”
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An alignment independent 3D QSAR study of the antiproliferative activity of 1,2,4,5-tetraoxanes by Cvijetić, Ilija N., Žižak, Željko P., Stanojković, Tatjana P., Juranić, Zorica D., Terzić, Nataša, Opsenica, Igor M., Opsenica, Dejan M., Juranić, Ivan O., Drakulić, Branko J.

“…An alignment-free 3D QSAR study on antiproliferative activity of the thirty-three 1,2,4,5-tetraoxane derivatives toward two human dedifferentiated cell lines…”
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Mixed tetraoxanes containing the acetone subunit as antimalarials by Opsenica, Dejan M., Terzić, Nataša, Smith, Philip L., Yang, Youngsun, Anova, Lalaine, Smith, Kirsten S., Šolaja, Bogdan A.

“…Eleven new tetraoxanes possessing cholic acid-derived carrier and isopropylidene moiety were synthesized and were tested in vitro and in vivo. In vitro…”
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Derivatives of Amodiaquine as Potent Human Cholinesterases Inhibitors: Implication for Treatment of Alzheimer’s Disease by Matošević, Ana, Opsenica, Dejan M., Bartolić, Marija, Maraković, Nikola, Stoilković, Andriana, Komatović, Katarina, Zandona, Antonio, Žunec, Suzana, Bosak, Anita

“…As some previously reported studies have proven that amodiaquine, in addition to its primary antimalarial activity, also has potential for new applications…”
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Antimalarial peroxides by DEJAN M. OPSENICA, BOGDAN A. ŠOLAJA

“…The problem of endemic malaria continues unabated globally. Malaria affects 40 % of the global population, causing an estimated annual mortality of 1.5–2.7…”
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Tetraoxanes as inhibitors of apicomplexan parasites Plasmodium falciparum and Toxoplasma gondii and anti-cancer molecules by Opsenica Dejan M., Radivojević Jelena, Matić Ivana Z., Štajner Tijana, Knežević-Ušaj Slavica, Đurković-Đaković Olgica, Šolaja Bogdan A.

“…New cyclohexylidene 1,2,4,5-tetraoxanes with polar guanidine and urea based groups were synthesized and evaluated for antimalarial activity against chloroquine…”
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Artemisinins and synthetic peroxides as highly efficient antimalarials by Dejan Milos Opsenica, Bogdan Aleksandar Šolaja

“…Malaria is devastating disease and global public health problem, with nearly half world population exposed to risk. Illness is caused by five Plasmodium…”
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Antimalarial, antimycobacterial and antiproliferative activity of phenyl substituted mixed tetraoxanes by Opsenica Dejan M., Dennis Kyle E., Wilbur Milhous K., Šolaja Bogdan A.

“…Mixed tetraoxanes of the 4"-phenyl-substituted cyclohexyl-spirotetraoxacyclohexyl- spirocholate series have been prepared and evaluated as possible…”
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Structure-activity relationship study of steroidal 1,2,4,5-tetraoxane animalarials using computational procedures by Bhattacharjee Apurba K., Carvalho Keith A., Opsenica Dejan M., Šolaja Bogdan A.

“…A three-dimensional QSAR pharmacophore model for antimalarial activity of steroidal 1,2,4,5-tetraoxanes was developed from a set of 17 substituted antimalarial…”
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7, 8, 15, 16-Tetraoxa-dispiro [5. 2. 5. 2]hexadecane-3-carboxylic acid derivatives and their antimalarial activity by Opsenica Igor, Terzić Nataša A., Opsenica Dejan M., Milhous Wilbur K., Šolaja Bogdan A.

“…Several C2 symmetrical mixed tetraoxanes were prepared starting from a gemdihydroperoxide and a ketone. The obtained tetraoxanes showed pronounced antimalarial…”
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Antimalarial peroxides: The first intramolecular 1,2,4,5-tetraoxane by Opsenica Dejan M., Pocsfalvi Gabriella, Milhous Wilburk K., Šolaja Bogdan A.

“…An intramolecular steroidal 1,2,4,5-tetraoxane has been synthesised in six steps starting from methyl3-oxo-7α,12α-diacetoxy-5β-cholan-24-oate. The synthesised…”
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