Search Results - "Opoku‐Acheampong, Alexander B."

Head‐up tilt does not enhance prostate tumor perfusion or oxygenation in young rats by Kunkel, Olivia N., Rand, Taylor A., Pyle, Joseph G., Baumfalk, Dryden R., Horn, Andrew G., Opoku‐Acheampong, Alexander B., Ade, Carl J., Musch, Timothy I., Ramsey, Michael W., Delp, Michael D., Behnke, Bradley J.

“…Solid tumors contain hypoxic regions that contribute to anticancer therapy resistance. Thus, mitigating tumor hypoxia may enhance the efficacy of radiation…”
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5α-reductase 1 mRNA levels are positively correlated with TRAMP mouse prostate most severe lesion scores by Opoku-Acheampong, Alexander B, Henningson, Jamie N, Beck, Amanda P, Lindshield, Brian L

“…The contribution of 5α-reductase 1 and 5α-reductase 2 to prostate cancer development and progression is not clearly understood. TRAMP mice are a common…”
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Preventive and therapeutic efficacy of finasteride and dutasteride in TRAMP mice by Opoku-Acheampong, Alexander B, Unis, Dave, Henningson, Jamie N, Beck, Amanda P, Lindshield, Brian L

“…The prostate cancer prevention trial (PCPT) and Reduction by dutasteride of Prostate Cancer Events (REDUCE) trial found that 5α-reductase (5αR) inhibitors…”
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The effect of finasteride and dutasteride on the growth of WPE1-NA22 prostate cancer xenografts in nude mice by Opoku-Acheampong, Alexander B, Nelsen, Michelle K, Unis, Dave, Lindshield, Brian L

“…5α-reductase 1 (5αR1) and 5α-reductase 2 (5αR2) convert testosterone into the more potent androgen dihydrotestosterone. 5αR2 is the main isoenzyme in normal…”
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The impact of finasteride and dutasteride treatments on proliferation, apoptosis, androgen receptor, 5α-reductase 1 and 5α-reductase 2 in TRAMP mouse prostates by Opoku-Acheampong, Alexander B., Henningson, Jamie N., Lindshield, Brian L.

“…Previously, we studied the effect of finasteride- or dutasteride-containing diets in male C57BL/6 TRAMP x FVB mice. Pre (6 weeks of age) and post (12 weeks of…”
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Newly formulated, protein quality-enhanced, extruded sorghum-, cowpea-, corn-, soya-, sugar- and oil-containing fortified-blended foods lead to adequate vitamin A and iron outcomes and improved growth compared with non-extruded CSB+ in rats by Delimont, Nicole M., Fiorentino, Nicole M., Opoku-Acheampong, Alexander B., Joseph, Michael V., Guo, Qingbin, Alavi, Sajid, Lindshield, Brian L.

“…Corn and soyabean micronutrient-fortified-blended foods (FBF) are commonly used for food aid. Sorghum and cowpeas have been suggested as alternative…”
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Exercise and the Tumor Microenvironment: Potential Therapeutic Implications by Wiggins, Jennifer M, Opoku-Acheampong, Alexander B, Baumfalk, Dryden R, Siemann, Dietmar W, Behnke, Bradley J

“…An imbalance in oxygen delivery to demand in solid tumors results in local areas of hypoxia leading to poor prognosis for the patient. We hypothesize that…”
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Impaired diaphragm resistance vessel vasodilation with prolonged mechanical ventilation by Horn, Andrew G, Davis, 3rd, Robert T, Baumfalk, Dryden R, Kunkel, Olivia N, Bruells, Christian S, McCullough, Danielle J, Opoku-Acheampong, Alexander B, Poole, David C, Behnke, Bradley J

“…Mechanical ventilation (MV) is a life-saving intervention, yet with prolonged MV (i.e., ≥6 h) there are time-dependent reductions in diaphragm blood flow and…”
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Blood flow responses to mild-intensity exercise in ectopic vs. orthotopic prostate tumors; dependence upon host tissue hemodynamics and vascular reactivity by Garcia, Emmanuel, Becker, Veronika G C, McCullough, Danielle J, Stabley, John N, Gittemeier, Elizabeth M, Opoku-Acheampong, Alexander B, Sieman, Dietmar W, Behnke, Bradley J

“…Given the critical role of tumor O2 delivery in patient prognosis and the rise in preclinical exercise oncology studies, we investigated tumor and host tissue…”
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Effects of prostate cancer and exercise training on left ventricular function and cardiac and skeletal muscle mass by Baumfalk, Dryden R, Opoku-Acheampong, Alexander B, Caldwell, Jacob T, Ade, Carl J, Copp, Steven W, Musch, Timothy I, Behnke, Bradley J

“…Prostate cancer was found to reduce cardiac and left ventricle (LV) masses in association with diminished exercise capacity in rats. We tested the hypothesis…”
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Effect of Saw Palmetto Supplements on Androgen-Sensitive LNCaP Human Prostate Cancer Cell Number and Syrian Hamster Flank Organ Growth by Opoku-Acheampong, Alexander B., Lindshield, Brian L., Penugonda, Kavitha

“…Saw palmetto supplements (SPS) are commonly consumed by men with prostate cancer. We investigated whether SPS fatty acids and phytosterols concentrations…”
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Effects of aging and exercise training on the dynamics of vasoconstriction in skeletal muscle resistance vessels by Gittemeier, Elizabeth M., Ericson, Tyler, Ghosh, Payal, Copp, Steven W., Opoku-Acheampong, Alexander B., Behnke, Bradley J.

“…It is unknown whether aging or exercise training affect the dynamics of arteriolar vasoconstriction. Purpose We hypothesized that old age will slow, and…”
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Effects of high-intensity training on prostate cancer-induced cardiac atrophy by Baumfalk, Dryden R, Opoku-Acheampong, Alexander B, Caldwell, Jacob T, Butenas, Alec L E, Horn, Andrew G, Kunkel, Olivia N, Copp, Steven W, Ade, Carl J, Musch, Timothy I, Behnke, Bradley J

“…Recent evidence suggests prostate cancer independent of treatment has atrophic effects on whole heart and left ventricular (LV) masses, associated with reduced…”
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Prostate cancer cell growth characteristics in serum and prostate-conditioned media from moderate-intensity exercise-trained healthy and tumor-bearing rats by Opoku-Acheampong, Alexander B, Baumfalk, Dryden R, Horn, Andrew G, Kunkel, Olivia N, Ganta, Charan K, McCullough, Danielle J, Siemann, Dietmar W, Muller-Delp, Judy, Behnke, Bradley J

“…Physical activity is associated with diminished risk of several cancers, and preclinical studies suggest exercise training may alter tumor cell growth in…”
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Prostate cancer reduces endurance exercise capacity in association with reductions in cardiac and skeletal muscle mass in the rat by Esau, Peter J, Gittemeier, Elizabeth M, Opoku-Acheampong, Alexander B, Rollins, Korynne S, Baumfalk, Dryden R, Poole, David C, Musch, Timothy I, Behnke, Bradley J, Copp, Steven W

“…Exercise capacity is reduced in prostate cancer patients concurrently treated with androgen deprivation therapy compared to healthy counterparts. We tested the…”
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5[alpha]-reductase 1 mRNA levels are positively correlated with TRAMP mouse prostate most severe lesion scores by Opoku-Acheampong, Alexander B, Henningson, Jamie N, Beck, Amanda P, Lindshield, Brian L

“…Background The contribution of 5[alpha]-reductase 1 and 5[alpha]-reductase 2 to prostate cancer development and progression is not clearly understood. TRAMP…”
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Effects of a Pre‐Clinical Model of Prostate Cancer on Left Ventricular Function in Sedentary and Exercise Trained Rats by Baumfalk, Dryden R., Opoku‐Acheampong, Alexander B., Caldwell, Jacob T., Ade, Carl J., Musch, Timothy I., Behnke, Bradley J.

“…Background Prostate cancer is the most common type of non‐skin cancer found in men making it a primary area of concern. Preliminary evidence suggests prostate…”
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The Effects of Prolonged Mechanical Ventilation on Diaphragm Arteriolar Response to Alpha‐Adrenergic Agonists by Horn, Andrew Gary, Baumfalk, Dryden R, Opoku‐Acheampong, Alexander B, Kunkel, Olivia N, Caldwell, Jacob T, Poole, David C, Behnke, Bradley J

“…Introduction Mechanical ventilation (MV) is a life‐saving intervention and is employed in Intensive Care Units across the world. Previous work has shown a…”
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Prostate Cancer Reduces Endurance Exercise Capacity in the Rat: Possible Roles of Reduced Cardiac Mass and Function by Rollins, Korynne S, Esau, Peter J, Gittemeier, Elizabeth M, Opoku‐Acheampong, Alexander B, Behnke, Bradley J, Copp, Steven W

“…Abstract only…”
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