Search Results - "Opler, M"

Use of a novel study insight analytics (SIA) methodology to improve PANSS data quality and signal detection in a global clinical trial in schizophrenia by Opler, M., Negash, S., Tatsumi, K., Liu, C., Komaroff, M., Capodilupo, G., Hasebe, M., Echevarria, B., Blattner, R., Citrome, L.

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Standardized training in the rating of the six-item positive and negative syndrome scale (PANSS-6) by Kølbæk, P., Dines, D., Hansen, J., Opler, M., Correll, C., Mors, O., Østergaard, S.

“…Introduction The six-item Positive And Negative Syndrome Scale (PANSS-6) is short psychometric valid scale quantifying the severity of core schizophrenia…”
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P02-135 - A pattern recognition matrix for placebo-response in schizophrenia by Opler, M

“…Objectives There is a need for real-time capability to detect inconsistencies in efficacy outcome measures and to predict individual-level or group-level…”
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Live birth sex ratios and father's geographic origins in Jerusalem, 1964–1976 by Groeger, J., Opler, M., Kleinhaus, K., Perrin, M. C., Calderon‐Margalit, R., Manor, O., Paltiel, O., Conley, D., Harlap, S., Malaspina, D.

“…Objective To examine whether ancestry influenced sex ratios of offspring in a birth cohort before parental antenatal sex selection influenced offspring sex…”
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EPA-0506 - Social cognition and it's correlates to functional outcomes in schizophrenia by Khan Rhodes, A, Lindenmayer, J, Gao, L, Opler, M

“…Background Deficits in social functioning, including communication, work, social skills, and community functioning, are a defining feature of schizophrenia…”
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EPA-0120 – Validation and normalization of the russian version of the positive and negative syndrome scale (PANSS-RU) in schizophrenia: preliminary findings by Ivanova, E, Reznik, A, Opler, M, Khan, A, Gao, L

“…Objectives The PANSS is utilized in clinical trials for assessment of psychopathology. In order to determine the status of a patient, comparisons within a…”
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EPA-0121 – How to measure social cognition in schizophrenia? a comparison of measurements by Lucic, L, Khan, A, Rothman, B, Gao, L, Peterson, T, Opler, M

“…Objectives Developing empirically sound measures for social cognition is a key step in improving the factors that contribute to deficits in social functioning…”
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P-1301 - Cross-cultural differences in the positive and negative syndrome scale (PANSS) among european and japanese raters by Rothman, B, Khan, A, Opler, M, Bhargava, L

“…Introduction In clinical trials, good inter-rater reliability reduces error and influences statistical power. PANSS rater differences across cultures are…”
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P.3.a.007 The impact of a data-monitoring programme implemented at study midpoint on PANSS score consistency by Yavorsky, C, DiClemente, G, Jovic, S, Opler, M

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C.02.05 Teaming up with patients: Together we can do better (how can we involve patients with depression in their treatment goals?) by Opler, M.

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P.3.f.001 The impact of language and culture on the delivery of standardised rater training for the PANSS across seven countries by DeFries, A, Yavorsky, C, Liechti, S, Opler, M

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Evaluation of side effects using the BARS, SAS and AIMS in pediatric psychopharmacologic studies by Zalsman, G, Opler, M, Steinberg, T, Apter, A, Weizman, A

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P-463 - Development of the brief episodic memory assessment (BEMA): a new scale for episodic memory in alzheimer's disease to complement one-plus-one in vivo diagnosis strategy by Yavorsky, C, Opler, M, Di Clemente, G, De Fries, A, Khan, A, Jovic, S

“…Introduction Recent advances in biomarker technology have allowed for the development of highly predictive tests for Alzheimer's disease (AD) when combined…”
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P-1329 - Early patterns of symptom profiles using the positive and negative syndrome scale (PANSS) to inform decisions on the expected response to treatment during clinical trials by Yavorsky, C, Opler, M, Di Clemente, G, De Fries, A, Jovic, S, Khan, A

“…Introduction Prognostic models discriminate between groups of individuals likely to experience better or worse outcomes and to predict response to treatment…”
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Tetrachloroethylene exposure and risk of schizophrenia: Offspring of dry cleaners in a population birth cohort, preliminary findings by Perrin, Mary C, Opler, Mark G, Harlap, Susan, Harkavy-Friedman, Jill, Kleinhaus, Karine, Nahon, Daniella, Fennig, Shmuel, Susser, Ezra S, Malaspina, Dolores

“…Abstract Tetrachloroethylene is a solvent used in dry cleaning with reported neurotoxic effects. Using proportional hazard methods, we examined the…”
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PW01-140 - Three levels of rater performance in standardized PANSS training by Lo, G, Yavorsky, W, Opler, M, Defries, A

“…Objectives The importance of rater training for reliability and validity in clinical trials is well documented. In this study the authors examined data from…”
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PW01-139 - The impact of language and culture on the delivery of standardized rater training for the PANSS across seven countries by Yavorsky, W, Liechti, S, Defries, A, Opler, M

“…Objectives There is a considerable body of literature suggesting that standardized rater training is a critical element to achieving inter-rater reliability…”
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P-1390 - Prenatal stress and affective disorders in a population birth cohort by Kleinhaus, K, Harlap, S, Manor, O, Margalit-Calderon, R, Perrin, M, Opler, M, Lichtenberg, P, Malaspina, D

“…Background Maternal psychological stress during pregnancy has been associated with the risk for mood disorders in offspring, although there is no consensus…”
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P01-449 - Global inter-rater reliability, scale validity, and local perception: Panss ratings and reactions from 4 Countries by De Fries, A, Liechti, S, Opler, M, Lane, S, Ivanova, E, Yang, L

“…Introduction/objectives/aims We compared cohorts of raters from different countries who received training on the PANSS. We attempted to determine if there was…”
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P02-88 - Quantifying rater drift on the HAM-D in a sample of standardized rater training events: Implications for reliability and sample size calculations by Rothman, B, Yavorsky, C, De Fries, A, Gordon, J, Opler, M

“…Introduction/objectives/aims Though rater drift in clinical trials has long been understood to negatively impact trial results, few studies have systematically…”
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