Search Results - "Ophel, Jasper"

Engineering pan-HIV-1 neutralization potency through multispecific antibody avidity by Rujas, Edurne, Cui, Hong, Burnie, Jonathan, Aschner, Clare Burn, Zhao, Tiantian, Insausti, Sara, Muthuraman, Krithika, Semesi, Anthony, Ophel, Jasper, Nieva, Jose L, Seaman, Michael S, Guzzo, Christina, Treanor, Bebhinn, Julien, Jean-Philippe

“…Deep mining of B cell repertoires of HIV-1-infected individuals has resulted in the isolation of dozens of HIV-1 broadly neutralizing antibodies (bNAbs). Yet,…”
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Safety and antiviral activity of triple combination broadly neutralizing monoclonal antibody therapy against HIV-1: a phase 1 clinical trial by Julg, Boris, Stephenson, Kathryn E., Wagh, Kshitij, Tan, Sabrina C., Zash, Rebecca, Walsh, Stephen, Ansel, Jessica, Kanjilal, Diane, Nkolola, Joseph, Walker-Sperling, Victoria E. K., Ophel, Jasper, Yanosick, Katherine, Borducchi, Erica N., Maxfield, Lori, Abbink, Peter, Peter, Lauren, Yates, Nicole L., Wesley, Martina S., Hassell, Tom, Gelderblom, Huub C., deCamp, Allen, Mayer, Bryan T., Sato, Alicia, Gerber, Monica W., Giorgi, Elena E., Gama, Lucio, Koup, Richard A., Mascola, John R., Monczor, Ana, Lupo, Sofia, Rolle, Charlotte-Paige, Arduino, Roberto, DeJesus, Edwin, Tomaras, Georgia D., Seaman, Michael S., Korber, Bette, Barouch, Dan H.

“…HIV-1 therapy with single or dual broadly neutralizing antibodies (bNAbs) has shown viral escape, indicating that at least a triple bNAb therapy may be needed…”
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