Search Results - "Opelt, Marissa"

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  1. 1

    Irreversible Activation and Stabilization of Soluble Guanylate Cyclase by the Protoporphyrin IX Mimetic Cinaciguat by Kollau, Alexander, Opelt, Marissa, Wölkart, Gerald, Gorren, Antonius C F, Russwurm, Michael, Koesling, Doris, Mayer, Bernd, Schrammel, Astrid

    Published in Molecular pharmacology (01-02-2018)
    “…Belonging to the class of so-called soluble guanylate cyclase (sGC) activators, cinaciguat and BAY 60-2770 are interesting therapeutic tools for the treatment…”
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    Journal Article
  2. 2

    Formation of Nitric Oxide by Aldehyde Dehydrogenase-2 Is Necessary and Sufficient for Vascular Bioactivation of Nitroglycerin by Opelt, Marissa, Eroglu, Emrah, Waldeck-Weiermair, Markus, Russwurm, Michael, Koesling, Doris, Malli, Roland, Graier, Wolfgang F., Fassett, John T., Schrammel, Astrid, Mayer, Bernd

    Published in The Journal of biological chemistry (11-11-2016)
    “…Aldehyde dehydrogenase-2 (ALDH2) catalyzes vascular bioactivation of the antianginal drug nitroglycerin (GTN), resulting in activation of soluble guanylate…”
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    Journal Article
  3. 3

    Real-time visualization of distinct nitric oxide generation of nitric oxide synthase isoforms in single cells by Eroglu, Emrah, Hallström, Seth, Bischof, Helmut, Opelt, Marissa, Schmidt, Kurt, Mayer, Bernd, Waldeck-Weiermair, Markus, Graier, Wolfgang F., Malli, Roland

    Published in Nitric oxide (01-11-2017)
    “…The members of the nitric oxide synthase (NOS) family, eNOS, nNOS and iNOS, are well-characterized enzymes. However, due to the lack of suitable direct NO…”
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    Journal Article
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    Aldehyde dehydrogenase-independent bioactivation of nitroglycerin in porcine and bovine blood vessels by Neubauer, Regina, Wölkart, Gerald, Opelt, Marissa, Schwarzenegger, Christine, Hofinger, Marielies, Neubauer, Andrea, Kollau, Alexander, Schmidt, Kurt, Schrammel, Astrid, Mayer, Bernd

    Published in Biochemical pharmacology (15-02-2015)
    “…The vascular bioactivation of the antianginal drug nitroglycerin (GTN), yielding 1,2-glycerol dinitrate and nitric oxide or a related activator of soluble…”
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    Journal Article
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