Search Results - "Opalka, B."

Differential expression of drug-resistance-related genes between sensitive and resistant blasts in acute myeloid leukemia by Eisele, L, Klein-Hitpass, L, Chatzimanolis, N, Opalka, B, Boes, T, Seeber, S, Moritz, T, Flasshove, M

“…Drug resistance constitutes a considerable problem in the therapy of acute myeloid leukemia (AML). In order to identify genes which might be related to drug…”
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MP-02.08 Identification of Cancer-Stem-Cell-Like Cells in a Papillary Renal Cell Carcinoma-Derived Cell Line by Börger, V, Rottke, D, Sorg, U, Heikaus, S, Opalka, B, Ackermann, R, Wernet, P, Sorg, R

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UP-01.149 Immunophenotype, Differentiation Capacity and Tumor Promoting Potential of Renal Cell Carcinoma-Derived Mesenchymal Stem Cell-Like Stromal Cells by Börger, V, Rottke, D, Sorg, U, Hatina, J, Heikaus, S, Opalka, B, Ackermann, R, Wernet, P, Sorg, R

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Thalidomide in combination with vincristine, epirubicin and dexamethasone (VED) for previously untreated patients with multiple myeloma by Schütt, P., Ebeling, P., Buttkereit, U., Brandhorst, D., Opalka, B., Hoiczyk, M., Flasshove, M., Hense, J., Bojko, P., Metz, K., Moritz, T., Seeber, S., Nowrousian, M. R.

“…:  The present study aimed to evaluate the side‐effects and efficacy of thalidomide in combination with an anthracycline‐containing chemotherapy regimen in…”
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460. MGMTP140K Vector Constructs for Efficient In Vivo Enrichment of Genetically Corrected Cells Following Hematopoietic Cell Gene Transfer by Sorg, U.R., Kleff, V., Nagel, G., Opalka, B., Thomale, J., Kaina, B., Moritz, T.

“…MGMTP140K , a mutant of the DNA repair protein O6 -methylguanine-DNA methyltransferase (MGMT) resistant to the inhibitor O6 -benzylguanine (BG), protects…”
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Thalidomide in combination with dexamethasone for pretreated patients with multiple myeloma: serum level of soluble interleukin-2 receptor as a predictive factor for response rate and for survival by Schütt, Philipp, Ebeling, Peter, Buttkereit, Ulrike, Brandhorst, Dieter, Opalka, Bertram, Poser, Miriam, Müller, Siemke, Flasshove, Michael, Moritz, Thomas, Seeber, Siegfried, Nowrousian, Mohammad Resa

“…The aim of this study was to assess the side effects and the efficacy of thalidomide alone or in combination with dexamethasone in relapsed multiple myeloma…”
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Cellular in vitro immune function in multiple myeloma patients after high-dose chemotherapy and autologous peripheral stem cell transplantation by LINDEMANN, M, SCHUETT, P, MORITZ, T, OTTINGER, H. D, OPALKA, B, SEEBER, S, NOWROUSIAN, M. R, GROSSE-WILDE, H

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Interferon alfa as primary treatment of chronic myeloid leukemia : long-term follow-up of 71 patients observed in a single center by KLOKE, O, OPALKA, B, NIEDERLE, N

“…The purpose of this study was to evaluate the long-term outcome of interferon (IFN) alfa treatment in patients with Philadelphia chromosome-positive chronic…”
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The amount of BCR-ABL fusion transcripts detected by the real-time quantitative polymerase chain reaction method in patients with Philadelphia chromosome positive chronic myeloid leukemia correlates with the disease stage by ELMAAGACLI, A. H, BEELEN, D. W, OPALKA, B, SEEBER, S, SCHAEFER, U. W

“…The use of the real-time reverse-transcription polymerase-chain reaction (RT-PCR) method to quantify BCR-ABL transcripts before and after allogeneic transplant…”
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Age distribution of latent herpes simplex virus 1 and varicella-zoster virus genome in human nervous tissue by Liedtke, W, Opalka, B, Zimmermann, C W, Lignitz, E

“…Latency in nervous tissue caused by herpes simplex virus 1 (HSV-1) and by varicella-zoster virus (VZV) is an intriguing feature of herpes-virus' neurotropism…”
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A comparison of chimerism and minimal residual disease between four different allogeneic transplantation methods in patients with chronic myelogenous leukemia in first chronic phase by ELMAAGACLI, A. H, RUNKEL, K, STECKEL, N, OPALKA, B, TRENSCHEL, R, SEEBER, S, SCHAEFER, U. W, BEELEN, D. W

“…The detection of chimerism, residual molecular and cytogenetic disease following transplantation of peripheral blood stem cells (PBSCT) with a nonmyeloablative…”
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E1A overcomes the apoptosis block in BCR-ABL+ leukemia cells and renders cells susceptible to induction of apoptosis by chemotherapeutic agents by STIEWE, T, PARSSANEDJAD, K, ESCHE, H, OPALKA, B, PÜTZER, B. M

“…A crucial function of the BCR-ABL chimeric gene in chronic myeloid leukemia is the prolongation of cell survival by inhibition of apoptosis. BCR-ABL expression…”
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Type and position of promoter elements in retroviral vectors have substantial effects on the expression level of an enhanced green fluorescent protein reporter gene by FLASSHOVE, M, BARDENHEUER, W, SCHNEIDER, A, HIRSCH, G, BACH, P, BURY, C, MORITZ, T, SEEBER, S, OPALKA, B

“…Although gene transfer with retroviral vectors has already been applied to patients as part of clinical protocols, low expression of transgenes in target cells…”
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In vitro dendritic cell generation and lymphocyte subsets in myeloma patients: influence of thalidomide and high-dose chemotherapy treatment by SCHÜTT, Philipp, BUTTKEREIT, Ulrike, BRANDHORST, Dieter, LINDEMANN, Monika, SCHMIEDL, Sven, GROSSE-WILDE, Hans, SEEBER, Siegfried, MOHAMMAD RESA NOWROUSIAN, OPALKA, Bertram, MORITZ, Thomas

“…While vaccination with antigen-pulsed dendritic cells (DCs) represents a promising therapeutic strategy in multiple myeloma (MM), clinical benefit, so far, has…”
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Acute myeloid leukemia cells polarize macrophages towards a leukemia supporting state in a Growth factor independence 1 dependent manner by Al-Matary, Yahya S, Botezatu, Lacramioara, Opalka, Bertram, Hönes, Judith M, Lams, Robert F, Thivakaran, Aniththa, Schütte, Judith, Köster, Renata, Lennartz, Klaus, Schroeder, Thomas, Haas, Rainer, Dührsen, Ulrich, Khandanpour, Cyrus

“…The growth of malignant cells is not only driven by cell-intrinsic factors, but also by the surrounding stroma. Monocytes/Macrophages play an important role in…”
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Novel Tumor Suppressor Locus in Human Chromosome Region 3p14.2 by Jülicher, Knut, Marquitan, Guido, Werner, Nicola, Bardenheuer, Walter, Vieten, Lydia, Bröcker, Frank, Topal, Hüsnü, Seeber, Siegfried, Opalka, Bertram, Schütte, Jochen

“…BACKGROUND: Alterations of chromosome region 3p14 are observed in numerous human malignancies. Because the pattern of allelic losses suggests the existence of…”
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Analysis of inversions and sister chromatid exchanges in chromosome 3 of human lymphocytes exposed to X-rays by Wojcik, Andrzej, Opalka, Bertram, Obe, Günter

“…It has been shown repeatedly that exposure of G1 cells unifilarily labelled with 5-bromodeoxyuridine (BrdU) to X-rays leads to sister chromatid exchanges (SCE)…”
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Transplantation of highly purified HLA-identical sibling donor peripheral blood CD34+ cells without prophylactic post-transplant immunosuppression in adult patients with first chronic phase chronic myeloid leukemia : results of a phase II study by BEELEN, D. W, PECENY, R, ELMAAGACLI, A, OTTINGER, H, KUMMER, G, OPALKA, B, SEEBER, S, SCHAEFER, U. W

“…The feasibility of transplantation using highly purified G-CSF-mobilized peripheral blood CD34+ cells from HLA-identical sibling donors without prophylactic…”
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Pluripotent stem cells escape from senescence-associated DNA methylation changes by Koch, Carmen M, Reck, Kristina, Shao, Kaifeng, Lin, Qiong, Joussen, Sylvia, Ziegler, Patrick, Walenda, Gudrun, Drescher, Wolf, Opalka, Bertram, May, Tobias, Brümmendorf, Tim, Zenke, Martin, Saric, Tomo, Wagner, Wolfgang

“…Pluripotent stem cells evade replicative senescence, whereas other primary cells lose their proliferation and differentiation potential after a limited number…”
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Impact of interferon alpha-induced cytogenetic improvement on survival in chronic myelogenous leukaemia by Kloke, O, Niederle, N, Qiu, J Y, Wandl, U, Moritz, T, Nagel-Hiemke, M, Hawig, I, Opalka, B, Seeber, S, Becher, R

“…The objective of this study was to investigate the prognostic impact of the reduction of Philadelphia chromosome (Ph) positive metaphases by treatment of…”
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