Search Results - "OpaliÅski, Åukasz"

The cytotoxic conjugate of highly internalizing tetravalent antibody for targeting FGFR1-overproducing cancer cells by Poźniak, Marta, Porębska, Natalia, Krzyścik, Mateusz Adam, Sokołowska-Wędzina, Aleksandra, Jastrzębski, Kamil, Sochacka, Martyna, Szymczyk, Jakub, Zakrzewska, Małgorzata, Otlewski, Jacek, Opaliński, Łukasz

“…Antibody drug conjugates (ADCs) represent one of the most promising approaches in the current immuno-oncology research. The precise delivery of cytotoxic drugs…”
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The diverse dependence of galectin-1 and -8 on multivalency for the modulation of FGFR1 endocytosis by Żukowska, Dominika, Chorążewska, Aleksandra, Ciura, Krzysztof, Gędaj, Aleksandra, Kalka, Marta, Poźniak, Marta, Porębska, Natalia, Opaliński, Łukasz

“…Fibroblast growth factor receptor 1 (FGFR1) is a N-glycosylated cell surface receptor tyrosine kinase, which upon recognition of specific extracellular…”
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Differential regulation of fibroblast growth factor receptor 1 trafficking and function by extracellular galectins by Kucińska, Marika, Porębska, Natalia, Lampart, Agata, Latko, Marta, Knapik, Agata, Zakrzewska, Małgorzata, Otlewski, Jacek, Opaliński, Łukasz

“…Fibroblast growth factor receptors (FGFRs) are integral membrane proteins that transmit signals through the plasma membrane. FGFRs signaling needs to be…”
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Modular self-assembly system for development of oligomeric, highly internalizing and potent cytotoxic conjugates targeting fibroblast growth factor receptors by Poźniak, Marta, PorÄbska, Natalia, JastrzÄbski, Kamil, KrzyÅcik, Mateusz Adam, KuciÅska, Marika, Zarzycka, Weronika, Barbach, Agnieszka, Zakrzewska, MaÅgorzata, Otlewski, Jacek, MiÄczyÅska, Marta, OpaliÅski, Åukasz

“…Background Overexpression of FGFR1 is observed in numerous tumors and therefore this receptor constitutes an attractive molecular target for selective cancer…”
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The intracellular interplay between galectin-1 and FGF12 in the assembly of ribosome biogenesis complex by Gędaj, Aleksandra, Chorążewska, Aleksandra, Ciura, Krzysztof, Karelus, Radosław, Żukowska, Dominika, Biaduń, Martyna, Kalka, Marta, Zakrzewska, Małgorzata, Porębska, Natalia, Opaliński, Łukasz

“…Galectins constitute a class of lectins that specifically interact with β-galactoside sugars in glycoconjugates and are implicated in diverse cellular…”
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