Search Results - "Op den Buijsch, Robert A.M."
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Tacrolimus pharmacokinetics and pharmacogenetics: influence of adenosine triphosphate-binding cassette B1 (ABCB1) and cytochrome (CYP) 3A polymorphisms
Published in Fundamental & clinical pharmacology (01-08-2007)“…Tacrolimus, an immunosuppressant used after organ transplantation, has a narrow therapeutic range and its pharmacokinetic variability complicates its daily…”
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Journal Article Conference Proceeding -
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Genotyping with a dried blood spot method: A useful technique for application in pharmacogenetics
Published in Clinica chimica acta (01-02-2008)“…Several commercial DNA isolation kits are available for extracting the genomic DNA from the ethylene diamine tetra-acetic acid (EDTA) whole blood samples. To…”
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Journal Article -
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Evaluation of limited sampling strategies for tacrolimus
Published in European journal of clinical pharmacology (01-11-2007)“…In literature, a great diversity of limited sampling strategies (LSS) have been recommended for tacrolimus monitoring, however proper validation of these…”
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Journal Article -
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Influence of different allelic variants of the CYP3A and ABCB1 genes on the tacrolimus pharmacokinetic profile of Chinese renal transplant recipients
Published in Pharmacogenomics (01-06-2006)“…Tacrolimus has a narrow therapeutic window and a wide interindividual variation in its pharmacokinetics. The cytochrome P450 3A (CYP3A) and the ATP-binding…”
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Journal Article -
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Capillary electrophoretic detection in apolipoprotein E genotyping
Published in Electrophoresis (01-06-2002)“…We describe the application of capillary electrophoresis to detect DNA fragments, obtained after amplifying a part of the apolipoprotein E (apoE) gene with…”
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Journal Article -
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Comparison of DNA Isolation Kits to Extract DNA from Whole Blood Samples
Published in Current genomics (01-04-2006)“…Genomic DNA from WBCs is widely often used for PCR. Although kits for DNA isolation are in common use, there is scarce information about their performance and…”
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Journal Article