Search Results - "Oostvogels, A A M"
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Gene-expression-based T-Cell-to-Stroma Enrichment (TSE) score predicts response to immune checkpoint inhibitors in urothelial cancer
Published in Nature communications (14-02-2024)“…Immune checkpoint inhibitors (ICI) improve overall survival in patients with metastatic urothelial cancer (mUC), but therapeutic success at the individual…”
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Case Report: Adequate T and B Cell Responses in a SARS-CoV-2 Infected Patient After Immune Checkpoint Inhibition
Published in Frontiers in immunology (04-02-2021)“…After the COVID-19 outbreak, non-evidence based guidelines were published to advise clinicians on the adjustment of oncological treatment during this pandemic…”
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CD45RA + CCR7 - CD8 T cells lacking co-stimulatory receptors demonstrate enhanced frequency in peripheral blood of NSCLC patients responding to nivolumab
Published in Journal for immunotherapy of cancer (08-06-2019)“…Checkpoint inhibitors have become standard care of treatment for non-small cell lung cancer (NSCLC), yet only a limited fraction of patients experiences…”
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Serum cytokine levels are associated with tumor progression during FOLFIRINOX chemotherapy and overall survival in pancreatic cancer patients
Published in Frontiers in immunology (25-08-2022)“…Biomarkers predicting treatment response may be used to stratify patients with pancreatic ductal adenocarcinoma (PDAC) for available therapies. The aim of this…”
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A blood-based immune marker for resistance to pembrolizumab in patients with metastatic urothelial cancer
Published in Cancer Immunology, Immunotherapy (01-03-2023)“…PD1 inhibition is effective in patients with metastatic urothelial cancer (mUC), yet a large fraction of patients does not respond. In this study, we aimed to…”
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Analyzing Flow Cytometry or Targeted Gene Expression Data Influences Clinical Discoveries—Profiling Blood Samples of Pancreatic Ductal Adenocarcinoma Patients
Published in Cancers (31-08-2023)“…Introduction: Monitoring the therapeutic response of pancreatic ductal adenocarcinoma (PDAC) patients is crucial to determine treatment strategies. Several…”
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Anti-PD-1 Efficacy in Patients with Metastatic Urothelial Cancer Associates with Intratumoral Juxtaposition of T Helper-Type 1 and CD8 + T cells
Published in Clinical cancer research (01-01-2022)“…PD-1 inhibition results in durable antitumor responses in a proportion of patients with metastatic urothelial cancer (mUC). The majority of patients, however,…”
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Gestational diabetes mellitus among Sub-Saharan African and Surinamese women in the Netherlands
Published in Diabetes research and clinical practice (01-10-2020)“…•Five to sevenfold higher risk of GDM in Ghanaian and other Sub-Saharan African women compared to ethnic Dutch women.•Higher risk of GDM in Surinamese women…”
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Maternal and paternal family history of diabetes in second-degree relatives and metabolic outcomes at age 5–6 years: The ABCD Study
Published in Diabetes & metabolism (01-09-2017)“…Abstract Aim To investigate whether children with a family history of diabetes (FHD) in second-degree relatives (grandparents, aunts/uncles) are at increased…”
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Use of DALYs in economic analyses on interventions for infectious diseases: a systematic review
Published in Epidemiology and infection (01-07-2015)“…A systematic literature review was performed on full economic evaluations of infectious disease interventions using disability-adjusted life years (DALY) as…”
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