Search Results - "Oosterhout, Joep J"

Assessment of Second-Line Antiretroviral Regimens for HIV Therapy in Africa by Paton, Nicholas I, Kityo, Cissy, Hoppe, Anne, Reid, Andrew, Kambugu, Andrew, Lugemwa, Abbas, van Oosterhout, Joep J, Kiconco, Mary, Siika, Abraham, Mwebaze, Raymond, Abwola, Mary, Abongomera, George, Mweemba, Aggrey, Alima, Hillary, Atwongyeire, Dickens, Nyirenda, Rose, Boles, Justine, Thompson, Jennifer, Tumukunde, Dinah, Chidziva, Ennie, Mambule, Ivan, Arribas, Jose R, Easterbrook, Philippa J, Hakim, James, Walker, A. Sarah, Mugyenyi, Peter

“…Appropriate second-line antiretroviral therapy for HIV infection is needed in resource-limited settings. In a comparison of three protease-inhibitor–based…”
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Association of Human Leukocyte Antigen Alleles and Nevirapine Hypersensitivity in a Malawian HIV-Infected Population by Carr, Daniel F., Chaponda, Mas, Jorgensen, Andrea L., Castro, Elena Cornejo, van Oosterhout, Joep J., Khoo, Saye H., Lalloo, David G., Heyderman, Robert S., Alfirevic, Ana, Pirmohamed, Munir

“…Background. The nonnucleoside reverse transcriptase inhibitor nevirapine is the cornerstone of treatment for human immunodeficiency virus (HIV) in many…”
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The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy by HOSSEINIPOUR, Mina C, VAN OOSTERHOUT, Joep J. G, WEIGEL, Ralf, PHIRI, Sam, KAMWENDO, Debbie, PARKIN, Neil, FISCUS, Susan A, NELSON, Julie A. E, ERON, Joseph J, KUMWENDA, Johnstone

“…Over 150,000 Malawians have started antiretroviral therapy (ART), in which first-line therapy is stavudine/lamivudine/nevirapine. We evaluated drug resistance…”
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High rate of uncontrolled hypertension among adults receiving integrated HIV and hypertension care with aligned multi‐month dispensing in Malawi: results from a cross‐sectional survey and retrospective chart review by Whitehead, Hannah S., Phiri, Khumbo, Kalande, Pericles, Oosterhout, Joep J., Talama, George, Phiri, Sam, Moucheraud, Corrina, Moses, Agnes, Hoffman, Risa M.

“…Introduction People living with HIV have high rates of hypertension. Integrated HIV and hypertension care with aligned multi‐month dispensing of medications…”
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Virological failure, HIV-1 drug resistance, and early mortality in adults admitted to hospital in Malawi: an observational cohort study by Gupta-Wright, Ankur, Fielding, Katherine, van Oosterhout, Joep J, Alufandika, Melanie, Grint, Daniel J, Chimbayo, Elizabeth, Heaney, Judith, Byott, Matthew, Nastouli, Eleni, Mwandumba, Henry C, Corbett, Elizabeth L, Gupta, Ravindra K

“…Antiretroviral therapy (ART) scale-up in sub-Saharan Africa combined with weak routine virological monitoring has driven increasing HIV drug resistance. We…”
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Dysregulated Humoral Immunity to Nontyphoidal Salmonella in HIV-Infected African Adults by MacLennan, Calman A, Gilchrist, James J, Gordon, Melita A, Cunningham, Adam F, Cobbold, Mark, Goodall, Margaret, Kingsley, Robert A, van Oosterhout, Joep J.G, Msefula, Chisomo L, Mandala, Wilson L, Leyton, Denisse L, Marshall, Jennifer L, Gondwe, Esther N, Bobat, Saeeda, López-Macías, Constantino, Doffinger, Rainer, Henderson, Ian R, Zijlstra, Eduard E, Dougan, Gordon, Drayson, Mark T, MacLennan, Ian C.M, Molyneux, Malcolm E

“…Nontyphoidal Salmonellae are a major cause of life-threatening bacteremia among HIV-infected individuals. Although cell-mediated immunity controls…”
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Adjunctive Dexamethasone in HIV-Associated Cryptococcal Meningitis by Beardsley, Justin, Wolbers, Marcel, Kibengo, Freddie M, Ggayi, Abu-Baker M, Kamali, Anatoli, Cuc, Ngo Thi Kim, Binh, Tran Quang, Chau, Nguyen Van Vinh, Farrar, Jeremy, Merson, Laura, Phuong, Lan, Thwaites, Guy, Van Kinh, Nguyen, Thuy, Pham Thanh, Chierakul, Wirongrong, Siriboon, Suwatthiya, Thiansukhon, Ekkachai, Onsanit, Satrirat, Supphamongkholchaikul, Watthanapong, Chan, Adrienne K, Heyderman, Robert, Mwinjiwa, Edson, van Oosterhout, Joep J, Imran, Darma, Basri, Hasan, Mayxay, Mayfong, Dance, David, Phimmasone, Prasith, Rattanavong, Sayaphet, Lalloo, David G, Day, Jeremy N

“…The role of glucocorticoids in the treatment of bacterial or fungal meningitis is controversial. In this trial, adjunctive dexamethasone therapy in patients…”
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Retention in care during the first 3 years of antiretroviral therapy for women in Malawi's option B+ programme: an observational cohort study by Haas, Andreas D, MA, Tenthani, Lyson, MPH, Msukwa, Malango T, BSc, Tal, Kali, PhD, Jahn, Andreas, PhD, Gadabu, Oliver J, MPH, Spoerri, Adrian, PhD, Chimbwandira, Frank, MBBS, van Oosterhout, Joep J, Prof, Keiser, Olivia, PhD

“…Summary Background Studies of Malawi's option B+ programme for HIV-positive pregnant and breastfeeding women have reported high loss to follow-up during…”
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Prevention of mother-to-child transmission of HIV and the health-related Millennium Development Goals: time for a public health approach by Schouten, Erik J, Dr, Jahn, Andreas, PhD, Midiani, Dalitso, BSc, Makombe, Simon D, Dipl Clin Med, Mnthambala, Austin, MPH, Chirwa, Zengani, MBCh, Harries, Anthony D, Prof, van Oosterhout, Joep J, Prof, Meguid, Tarek, MD, Ben-Smith, Anne, PhD, Zachariah, Rony, PhD, Lynen, Lutgarde, PhD, Zolfo, Maria, MD, Van Damme, Wim, Prof, Gilks, Charles F, Prof, Atun, Rifat, Prof, Shawa, Mary, PhD, Chimbwandira, Frank, MBBS

“…The logistics of delivery will be improved, the risks of running out of stocks lessened, the need for multiple guidelines and training eliminated, and the…”
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The National Evaluation of Malawi’s PMTCT Program (NEMAPP) study: 24‐month HIV‐exposed infant outcomes from a prospective cohort study by Lettow, Monique, Tippett Barr, Beth A., Oosterhout, Joep J., Schouten, Erik, Jahn, Andreas, Kalua, Thokozani, Auld, Andrew, Nyirenda, Rose, Wadonda, Nellie, Kim, Evelyn, Landes, Megan

“…Objectives Data on long‐term HIV‐free survival in breastfeeding, HIV‐exposed infants (HEIs) are limited. The National Evaluation of Malawi’s Prevention of…”
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Effect of cardio-metabolic risk factors on all-cause mortality among HIV patients on antiretroviral therapy in Malawi: A prospective cohort study by Amberbir, Alemayehu, Banda, Victor, Singano, Victor, Matengeni, Alfred, Pfaff, Colin, Ismail, Zahra, Allain, Theresa J, Chan, Adrienne K, Sodhi, Sumeet K, van Oosterhout, Joep J

“…Cardiovascular disease (CVD) risk among people living with HIV is elevated due to persistent inflammation, hypertension and diabetes comorbidity, lifestyle…”
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Pregnancy intention and contraceptive use among HIV-positive Malawian women at 4-26 weeks post-partum: A nested cross-sectional study by Thindwa, Deus, Landes, Megan, van Lettow, Monique, Kanyemba, Annie, Nkhoma, Ernest, Phiri, Happy, Kalua, Thokozani, van Oosterhout, Joep J, Kim, Evelyn J, Barr, Beth A Tippett

“…Avoiding unintended pregnancies through family planning is a WHO strategy for preventing mother to child transmission of HIV (PMTCT) and maternal…”
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Retention on antiretroviral therapy during Universal Test and Treat implementation in Zomba district, Malawi: a retrospective cohort study by Alhaj, Mohammad, Amberbir, Alemayehu, Singogo, Emmanuel, Banda, Victor, Lettow, Monique, Matengeni, Alfred, Kawalazira, Gift, Theu, Joe, Jagriti, Megh R, Chan, Adrienne K, Oosterhout, Joep J

“…Introduction Since June 2016, the national HIV programme in Malawi has adopted Universal Test and Treat (UTT) guidelines requiring that all persons who test…”
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Same day HIV diagnosis and antiretroviral therapy initiation affects retention in Option B+ prevention of mother‐to‐child transmission services at antenatal care in Zomba District, Malawi by Chan, Adrienne K, Kanike, Emmanuel, Bedell, Richard, Mayuni, Isabel, Manyera, Ruth, Mlotha, William, Harries, Anthony D, Oosterhout, Joep J, Lettow, Monique

“…Introduction Data from the Option B+ prevention of mother‐to‐child transmission (PMTCT) program in Malawi show considerable variation between health facilities…”
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Low detectable postpartum viral load is associated with HIV transmission in Malawi's prevention of mother‐to‐child transmission programme by Landes, Megan, Lettow, Monique, Nkhoma, Ernest, Tippett Barr, Beth, Truwah, Zinenani, Shouten, Erik, Jahn, Andreas, Auld, Andrew, Kalua, Thokozani, Oosterhout, Joep J

“…Introduction In 2011, Malawi implemented “Option B+,” a test‐and‐treat strategy for the prevention of maternal to child transmission of HIV (PMTCT); however…”
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The burden of hypertension, diabetes mellitus, and cardiovascular risk factors among adult Malawians in HIV care: consequences for integrated services by Divala, Oscar H, Amberbir, Alemayehu, Ismail, Zahra, Beyene, Teferi, Garone, Daniela, Pfaff, Colin, Singano, Victor, Akello, Harriet, Joshua, Martias, Nyirenda, Moffat J, Matengeni, Alfred, Berman, Josh, Mallewa, Jane, Chinomba, Gift S, Kayange, Noel, Allain, Theresa J, Chan, Adrienne K, Sodhi, Sumeet K, van Oosterhout, Joep J

“…Hypertension and diabetes prevalence is high in Africans. Data from HIV infected populations are limited, especially from Malawi. Integrating care for chronic…”
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A simultaneous population pharmacokinetic analysis of rifampicin in Malawian adults and children by Schipani, Alessandro, Pertinez, Henry, Mlota, Rachel, Molyneux, Elizabeth, Lopez, Nuria, Dzinjalamala, Fraction K., Oosterhout, Joep J., Ward, Steve A., Khoo, Saye, Davies, Gerry

“…AIMS Low rifampicin plasma concentrations can lead to treatment failure and increased risk of developing drug resistant tuberculosis. The objectives of this…”
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Early post-partum viremia predicts long-term non-suppression of viral load in HIV-positive women on ART in Malawi: Implications for the elimination of infant transmission by Landes, Megan, van Lettow, Monique, van Oosterhout, Joep J, Schouten, Erik, Auld, Andrew, Kalua, Thokozani, Jahn, Andreas, Tippett Barr, Beth A

“…Long-term viral load (VL) suppression among HIV-positive, reproductive-aged women on ART is key to eliminating mother-to-child transmission (MTCT) but few data…”
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Brief Report: HIV Testing Among Pregnant Women Who Attend Antenatal Care in Malawi by Tenthani, Lyson, Haas, Andreas D, Egger, Matthias, Oosterhout, Joep J Van, Jahn, Andreas, Chimbwandira, Frank, Tal, Kali, Myer, Landon, Estill, Janne, Keiser, Olivia

“…Malawi adopted the Option B+ strategy in 2011. Its success in reducing mother-to-child transmission depends on coverage and timing of HIV testing. We assessed…”
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A targeted approach for routine viral load monitoring in Malawian adults on antiretroviral therapy by Mungwira, Randy G., Divala, Titus H., Nyirenda, Osward M., Kanjala, Maxwell, Muwalo, Francis, Mkandawire, Felix A., Choko, Augustine, Taylor, Terrie E., Mallewa, Jane, Oosterhout, Joep J., Laufer, Miriam K., Laurens, Matthew B.

“…Objectives WHO recommends HIV viral load (VL) testing 6 months after antiretroviral therapy (ART) initiation and every 12 months thereafter, but cost prohibits…”
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