Search Results - "Oosterheert, Wout"

Phalloidin and DNase I-bound F-actin pointed end structures reveal principles of filament stabilization and disassembly by Boiero Sanders, Micaela, Oosterheert, Wout, Hofnagel, Oliver, Bieling, Peter, Raunser, Stefan

“…Actin filament turnover involves subunits binding to and dissociating from the filament ends, with the pointed end being the primary site of filament…”
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Cryo-EM structures of human STEAP4 reveal mechanism of iron(III) reduction by Oosterheert, Wout, van Bezouwen, Laura S., Rodenburg, Remco N. P., Granneman, Joke, Förster, Friedrich, Mattevi, Andrea, Gros, Piet

“…Enzymes of the six-transmembrane epithelial antigen of the prostate (STEAP) family reduce Fe 3+ and Cu 2+ ions to facilitate metal-ion uptake by mammalian…”
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X-ray structures define human P2X3 receptor gating cycle and antagonist action by Mansoor, Steven E., Lü, Wei, Oosterheert, Wout, Shekhar, Mrinal, Tajkhorshid, Emad, Gouaux, Eric

“…P2X receptors are trimeric, non-selective cation channels activated by ATP that have important roles in the cardiovascular, neuronal and immune systems…”
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Cryo-electron microscopy structure and potential enzymatic function of human six-transmembrane epithelial antigen of the prostate 1 (STEAP1) by Oosterheert, Wout, Gros, Piet

“…Six-transmembrane epithelial antigen of the prostate 1 (STEAP1) is an integral membrane protein that is highly up-regulated on the cell surface of several…”
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The great escape — how inorganic phosphate is released from actin filaments

“…The release of inorganic phosphate (P i ) from actin marks old actin filaments for disassembly. By combining cryo-electron microscopy (cryo-EM) with in vitro…”
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X-ray structures define human P2X(3) receptor gating cycle and antagonist action by Mansoor, Steven E, Lü, Wei, Oosterheert, Wout, Shekhar, Mrinal, Tajkhorshid, Emad, Gouaux, Eric

“…P2X receptors are trimeric, non-selective cation channels activated by ATP that have important roles in the cardiovascular, neuronal and immune systems…”
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Structural basis of actin filament assembly and aging by Oosterheert, Wout, Klink, Björn U., Belyy, Alexander, Pospich, Sabrina, Raunser, Stefan

“…The dynamic turnover of actin filaments (F-actin) controls cellular motility in eukaryotes and is coupled to changes in the F-actin nucleotide state 1 – 3 . It…”
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An Elegant Four-Helical Fold in NOX and STEAP Enzymes Facilitates Electron Transport across BiomembranesSimilar Vehicle, Different Destination by Oosterheert, Wout, Reis, Joana, Gros, Piet, Mattevi, Andrea

“…Conspectus The ferric reductase superfamily comprises several oxidoreductases that use an intracellular electron source to reduce an extracellular acceptor…”
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Crystal structure of the second extracellular domain of human tetraspanin CD9: twinning and diffuse scattering by Neviani, Viviana, Lutz, Martin, Oosterheert, Wout, Gros, Piet, Kroon-Batenburg, Loes

“…Remarkable features are reported in the diffraction pattern produced by a crystal of the second extracellular domain of tetraspanin CD9 (deemed CD9 EC2 ), the…”
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Molecular mechanism of actin filament elongation by formins by Oosterheert, Wout, Boiero Sanders, Micaela, Funk, Johanna, Prumbaum, Daniel, Raunser, Stefan, Bieling, Peter

“…Formins control the assembly of actin filaments (F-actin) that drive cell morphogenesis and motility in eukaryotes. However, their molecular interaction with…”
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Molecular mechanisms of inorganic-phosphate release from the core and barbed end of actin filaments by Oosterheert, Wout, Blanc, Florian E. C., Roy, Ankit, Belyy, Alexander, Sanders, Micaela Boiero, Hofnagel, Oliver, Hummer, Gerhard, Bieling, Peter, Raunser, Stefan

“…The release of inorganic phosphate (P i ) from actin filaments constitutes a key step in their regulated turnover, which is fundamental to many cellular…”
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X-ray structures define human P2X^sub 3^ receptor gating cycle and antagonist action by Mansoor, Steven E, Lü, Wei, Oosterheert, Wout, Shekhar, Mrinal, Tajkhorshid, Emad, Gouaux, Eric

“…P2X receptors are trimeric, non-selective cation channels activated by ATP that have important roles in the cardiovascular, neuronal and immune systems…”
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Multifaceted Activities of Seven Nanobodies against Complement C4b by De la O Becerra, Karla I, Oosterheert, Wout, van den Bos, Ramon M, Xenaki, Katerina T, Lorent, Joseph H, Ruyken, Maartje, Schouten, Arie, Rooijakkers, Suzan H M, van Bergen En Henegouwen, Paul M P, Gros, Piet

“…Cleavage of the mammalian plasma protein C4 into C4b initiates opsonization, lysis, and clearance of microbes and damaged host cells by the classical and…”
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Implications for tetraspanin-enriched microdomain assembly based on structures of CD9 with EWI-F by Oosterheert, Wout, Xenaki, Katerina T, Neviani, Viviana, Pos, Wouter, Doulkeridou, Sofia, Manshande, Jip, Pearce, Nicholas M, Kroon-Batenburg, Loes MJ, Lutz, Martin, van Bergen en Henegouwen, Paul MP, Gros, Piet

“…Tetraspanins are eukaryotic membrane proteins that contribute to a variety of signaling processes by organizing partner-receptor molecules in the plasma…”
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