Search Results - "Oon, Chong Jin"

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    Long-term survival following treatment of hepatocellular carcinoma in Singapore : evaluation of Wellferon in the prophylaxis of high-risk pre-cancerous conditions by Oon, C J

    “…The present paper reviews several studies performed between 1977 and 1986 in Singapore on the 10-year survival outcome of treatment for stage I and II…”
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    Conference Proceeding Journal Article
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    Hepatitis B virus surface antigen (HBsAg) mutants in Singapore adults and vaccinated children with high anti-hepatitis B virus antibody levels but negative for HBsAg by Chen, W N, Oon, C J

    Published in Journal of clinical microbiology (01-07-2000)
    “…The hepatitis B virus (HBV) infection rate has been effectively reduced by universal vaccination. Concentrations of vaccine-induced neutralizing antibodies…”
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    Journal Article
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    Identification of Hepatitis B Surface Antigen Variants with Alterations outside the “a” Determinant in Immunized Singapore Infants by Chong-Jin, Oon, Ning, Chen Wei, Shiuan, Koh, Keow, Lim Gek

    Published in The Journal of infectious diseases (01-01-1999)
    “…Vaccine-associated hepatitis B surface antigen (HBsAg) mutations have been mainly identified within the “a” determinant (aa 124–147). Now changes have been…”
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    Journal Article
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    Molecular epidemiology of hepatitis B virus vaccine variants in Singapore by Oon, Chong-Jin, Lim, Gek-Keow, Ye, Zhao, Goh, Kee-Tai, Tan, Kim-Leong, Yo, Sui-Lan, Hopes, Elaine, Harrison, Tim J., Zuckerman, Arie J.

    Published in Vaccine (1995)
    “…Perinatal infection with variants of hepatitis B virus occurs despite combined immunoprophylaxis with hepatitis B immunoglobulin and currently licensed…”
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    Journal Article
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    Expression of Integrated Hepatitis B Virus X Variants in Human Hepatocellular Carcinomas and Its Significance by Chen, Wei Ning, Oon, Chong Jin, Leong, Ai Lin, Koh, Shiuan, Teng, Siaw Wei

    “…Hepatitis B virus X protein (HBX) has been implicated in the transactivation of diverse cellular genes and possibly also the pathogenesis of human…”
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    Journal Article
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    Lymphoblastoid Alpha-interferon In The Prevention Of Hepatocellular Carcinoma (Hcc) In High-risk Hbsag-positive Resected Cirrhotic Hcc Cases: A 14-Year Follow-up by Oon, Chong Jin, Chen, Wei Ning

    Published in Cancer investigation (01-01-2003)
    “…Hepatocellular carcinoma (HCC) is a leading cause of death worldwide. It is also a common long-term complication of chronic hepatitis B or C infections, with…”
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    Journal Article
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    Intra-familial Evidence of Horizontal Transmission of Hepatitis B Virus Surface Antigen Mutant G145R by Oon, Chong Jin, Chen, Wei Ning, Goo, Kian Sim, Goh, Kee Tai

    Published in The Journal of infection (01-11-2000)
    “…Objectives: To provide intra-familial evidence on the horizontal transmission of hepatitis B virus surface antigen (HBsAg) mutant G145R. Methods: Serum samples…”
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    Journal Article
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    Partial sequence analysis of the hepatitis C viral genome in Singapore patients by Lee, A S, Ng, K Y, Chee, M K, Vathsala, A, Choong, H L, Ng, H S, Oon, C J

    “…The distribution of hepatitis C viral (HCV) genotypes in Singapore has not been previously determined. We studied the sera of 40 Singapore patients which were…”
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    Journal Article
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    Detection of hepatitis B surface antigen mutants and their integration in human hepatocellular carcinoma by Oon, Chong Jin, Chen, Wei Ning, Zhao, Yi, Teng, Siaw Wei, Leong, Ai Lin

    Published in Cancer letters (08-02-1999)
    “…Vaccine escape hepatitis B virus surface antigen (HBsAg) mutants are capable of independent replication and have been implicated in acute hepatitis. We now…”
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    Journal Article
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    Hepatitis B virus variants with lamivudine-related mutations in the DNA polymerase and the ‘a’ epitope of the surface antigen are sensitive to ganciclovir by Jin Oon, Chong, Ning Chen, Wei, Lim, Nichole, Koh, Shiuan, Keow Lim, Gek, Lin Leong, Ai, San Tan, Gek

    Published in Antiviral research (01-04-1999)
    “…Lamivudine is a new antiviral agent effective against hepatitis B viral (HBV) infections but can result in virus–drug resistance associated with mutations in…”
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    Journal Article
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    Detection of hepatitis B virus surface antigen mutants in paraffin-embedded hepatocellular carcinoma tissues by Chen, W N, Oon, C J, Moh, M C

    Published in Virus genes (01-05-2000)
    “…The antigenic "a" determinant of the human hepatitis B virus surface antigen (HBsAg) is highly conserved and involved in inducing neutralizing antibody…”
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    Journal Article
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