Search Results - "Oomens, Cees W. J."

Pressure Induced Deep Tissue Injury Explained by Oomens, Cees W. J., Bader, Daniel L., Loerakker, Sandra, Baaijens, Frank

“…The paper describes the current views on the cause of a sub-class of pressure ulcers known as pressure induced deep tissue injury (DTI). A multi-scale approach…”
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A MRI-Compatible Combined Mechanical Loading and MR Elastography Setup to Study Deformation-Induced Skeletal Muscle Damage in Rats by Nelissen, Jules L, de Graaf, Larry, Traa, Willeke A, Schreurs, Tom J L, Moerman, Kevin M, Nederveen, Aart J, Sinkus, Ralph, Oomens, Cees W J, Nicolay, Klaas, Strijkers, Gustav J

“…Deformation of skeletal muscle in the proximity of bony structures may lead to deep tissue injury category of pressure ulcers. Changes in mechanical properties…”
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The relative contributions of compression and hypoxia to development of muscle tissue damage: an in vitro study by Gawlitta, Debby, Li, Wei, Oomens, Cees W J, Baaijens, Frank P T, Bader, Dan L, Bouten, Carlijn V C

“…Deep pressure ulcers develop in tissues subjected to sustained mechanical loading. Though it has been hypothesized that this damage mechanism results from…”
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A new method to evaluate the effects of shear on the skin by de Wert, Luuk A., Bader, Dan L., Oomens, Cees W. J., Schoonhoven, Lisette, Poeze, Martijn, Bouvy, Nicole D.

“…Currently, pressure ulcer preventive strategies focus mainly on pressure redistribution. Little attention is paid to reduce the harmful effects of shear‐force,…”
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Computational model predicts cell orientation in response to a range of mechanical stimuli by Obbink-Huizer, Christine, Oomens, Cees W. J., Loerakker, Sandra, Foolen, Jasper, Bouten, Carlijn V. C., Baaijens, Frank P. T.

“…To build anisotropic, mechanically functioning tissue, it is essential to understand how cells orient in response to mechanical stimuli. Therefore, a…”
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Temporal differences in the influence of ischemic factors and deformation on the metabolism of engineered skeletal muscle by Gawlitta, Debby, Oomens, Cees W. J, Bader, Dan L, Baaijens, Frank P. T, Bouten, Carlijn V. C

“…1 Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands; and 2 Department of Engineering, Queen Mary University…”
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Transport Profile of Cytokines in Epidermal Equivalents Subjected to Mechanical Loading by Cornelissen, Lisette H, Bronneberg, Debbie, Bader, Dan L, Baaijens, Frank P. T, Oomens, Cees W. J

“…Pressure ulcer risk assessment might be optimized by incorporating the soft tissue reaction to mechanical loading in the currently used risk assessment scales…”
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A new pressure ulcer conceptual framework by Coleman, Susanne, Nixon, Jane, Keen, Justin, Wilson, Lyn, McGinnis, Elizabeth, Dealey, Carol, Stubbs, Nikki, Farrin, Amanda, Dowding, Dawn, Schols, Jos M.G.A., Cuddigan, Janet, Berlowitz, Dan, Jude, Edward, Vowden, Peter, Schoonhoven, Lisette, Bader, Dan L., Gefen, Amit, Oomens, Cees W.J., Nelson, E. Andrea

“…Aim This paper discusses the critical determinants of pressure ulcer development and proposes a new pressure ulcer conceptual framework. Background Recent work…”
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Passive and active contributions to generated force and retraction in heart valve tissue engineering by van Vlimmeren, Marijke A. A., Driessen-Mol, Anita, Oomens, Cees W. J., Baaijens, Frank P. T.

“…In tissue engineered heart valves, cell-mediated stress development during culture results in leaflet retraction at time of implantation. This tissue…”
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Does subcutaneous adipose tissue behave as an (anti-)thixotropic material? by Geerligs, Marion, Peters, Gerrit W.M, Ackermans, Paul A.J, Oomens, Cees W.J, Baaijens, Frank P.T

“…Abstract Although subcutaneous adipose tissue undergoes large deformations on a daily basis, there is no adequate mechanical model to describe the transfer of…”
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Computational and experimental investigation of local stress fiber orientation in uniaxially and biaxially constrained microtissues by Obbink-Huizer, Christine, Foolen, Jasper, Oomens, Cees W. J., Borochin, Michael, Chen, Christopher S., Bouten, Carlijn V. C., Baaijens, Frank P. T.

“…The orientation of cells and associated F-actin stress fibers is essential for proper tissue functioning. We have previously developed a computational model…”
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Cytokine and chemokine release upon prolonged mechanical loading of the epidermis by Bronneberg, Debbie, Spiekstra, Sander W., Cornelissen, Lisette H., Oomens, Cees W. J., Gibbs, Susan, Baaijens, Frank P. T., Bouten, Catlijin V. C.

“…:  At this moment, pressure ulcer risk assessment is dominated by subjective measures and does not predict pressure ulcer development satisfactorily. Objective…”
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Predicting local cell deformations in engineered tissue constructs: a multilevel finite element approach by Breuls, Roel G M, Sengers, Bram G, Oomens, Cees W J, Bouten, Carlijn V C, Baaijens, Frank P T

“…A multilevel finite element approach is applied to predict local cell deformations in engineered tissue constructs. Cell deformations are predicted from…”
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Real-time subject-specific analyses of dynamic internal tissue loads in the residual limb of transtibial amputees by Portnoy, Sigal, van Haare, Judith, Geers, Richard P.J, Kristal, Anat, Siev-Ner, Itzhak, Seelen, Henk A.M, Oomens, Cees W.J, Gefen, Amit

“…Abstract Transtibial amputation (TTA) prosthetic-users may risk the integrity of their residuum while trying to maintain everyday activities. Compression of…”
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Magnetic resonance elastography of skeletal muscle deep tissue injury by Nelissen, Jules L., Sinkus, Ralph, Nicolay, Klaas, Nederveen, Aart J., Oomens, Cees W.J., Strijkers, Gustav J.

“…The current state‐of‐the‐art diagnosis method for deep tissue injury in muscle, a subcategory of pressure ulcers, is palpation. It is recognized that deep…”
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Compressive mechanical properties of atherosclerotic plaques—Indentation test to characterise the local anisotropic behaviour by Chai, Chen-Ket, Speelman, Lambert, Oomens, Cees W.J, Baaijens, Frank P.T

“…Abstract Accurate material models and associated parameters of atherosclerotic plaques are crucial for reliable biomechanical plaque prediction models. These…”
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Developing a pressure ulcer risk factor minimum data set and risk assessment framework by Coleman, Susanne, Nelson, E. Andrea, Keen, Justin, Wilson, Lyn, McGinnis, Elizabeth, Dealey, Carol, Stubbs, Nikki, Muir, Delia, Farrin, Amanda, Dowding, Dawn, Schols, Jos M.G.A., Cuddigan, Janet, Berlowitz, Dan, Jude, Edward, Vowden, Peter, Bader, Dan L., Gefen, Amit, Oomens, Cees W.J., Schoonhoven, Lisette, Nixon, Jane

“…Aim To agree a draft pressure ulcer risk factor Minimum Data Set to underpin the development of a new evidenced‐based Risk Assessment Framework. Background A…”
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Local axial compressive mechanical properties of human carotid atherosclerotic plaques—characterisation by indentation test and inverse finite element analysis by Chai, Chen-Ket, Akyildiz, Ali C, Speelman, Lambert, Gijsen, Frank J.H, Oomens, Cees W.J, van Sambeek, Marc R.H.M, van der Lugt, Aad, Baaijens, Frank P.T

“…Abstract The fibrous cap of an atherosclerotic plaque may be prone to rupture if the occurring stresses exceed the strength of the cap. Rupture can cause acute…”
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Predicting the optimal geometry of microneedles and their array for dermal vaccination using a computational model by Römgens, Anne M., Bader, Dan L., Bouwstra, Joke A., Oomens, Cees W. J.

“…Microneedle arrays have been developed to deliver a range of biomolecules including vaccines into the skin. These microneedles have been designed with a wide…”
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Cell death induced by mechanical compression on engineered muscle results from a gradual physiological mechanism by Wu, Yabin, van der Schaft, Daisy W.J, Baaijens, Frank P, Oomens, Cees W.J

“…Abstract Deep tissue injury (DTI), a type of pressure ulcer, arises in the muscle layers adjacent to bony prominences due to sustained mechanical loading. DTI…”
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