Search Results - "Ooboshi, H"

Phosphate Binders Prevent Phosphate-Induced Cellular Senescence of Vascular Smooth Muscle Cells and Vascular Calcification in a Modified, Adenine-Based Uremic Rat Model by Yamada, S., Tatsumoto, N., Tokumoto, M., Noguchi, H., Ooboshi, H., Kitazono, T., Tsuruya, K.

“…Clinical and experimental studies have reported that phosphate overload plays a central role in the pathogenesis of vascular calcification in chronic kidney…”
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Postischemic gene transfer of midkine, a neurotrophic factor, protects against focal brain ischemia by TAKADA, J, OOBOSHI, H, AGO, T, KITAZONO, T, YAO, H, KADOMATSU, K, MURAMATSU, T, IBAYASHI, S, IIDA, M

“…Gene therapy may be a promising approach for treatment of brain ischemia. In this study, we examined the effect of postischemic gene transfer of midkine, a…”
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Deterioration of pre-existing hemiparesis brought about by subsequent ipsilateral lacunar infarction by Ago, T, Kitazono, T, Ooboshi, H, Takada, J, Yoshiura, T, Mihara, F, Ibayashi, S, Iida, M

“…Mechanisms of post-stroke recovery are still poorly understood. Recent evidence suggests that cortical reorganisation in the unaffected hemisphere plays an…”
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Polymorphism in the sorbin and SH3-domain-containing-1 (SORBS1) gene and the risk of brain infarction in the Japanese population: the Fukuoka Stroke Registry and the Hisayama study by Hagiwara, N., Kitazono, T., Kamouchi, M., Kuroda, J., Ago, T., Hata, J., Ninomiya, T., Ooboshi, H., Kumai, Y., Yoshimura, S., Tamaki, K., Fujii, K., Nagao, T., Okada, Y., Toyoda, K., Nakane, H., Sugimori, H., Yamashita, Y., Wakugawa, Y., Kubo, M., Tanizaki, Y., Kiyohara, Y., Ibayashi, S., Iida, M.

“…Background and purpose:  Sorbin and SH3‐domain‐containing‐1 (SORBS1) is an important adaptor protein in insulin‐signalling pathway, and its genetic…”
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Selective induction of ΔFosB in the brain after transient forebrain ischemia accompanied by an increased expression of galectin-1, and the implication of ΔFosB and galectin-1 in neuroprotection and neurogenesis by Kurushima, H, Ohno, M, Miura, T, Nakamura, T Y, Horie, H, Kadoya, T, Ooboshi, H, Kitazono, T, Ibayashi, S, Iida, M, Nakabeppu, Y

“…Transient forebrain ischemia causes selective induction of Delta FosB, an AP-1 (activator protein-1) subunit, in cells within the ventricle wall or those in…”
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Cerebral sinus thrombosis in a patient with Cushing’s syndrome by Yoshimura, S, Ago, T, Kitazono, T, Yonekura, T, Kumai, Y, Kuroda, J, Kamouchi, M, Ooboshi, H, Ibayashi, S, Iida, M

“…Factor VIII is mainly synthesised in the liver and secreted to the circulation. Because VWF protects factor VIII from proteases, a concordant increase of…”
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Elevated cerebrospinal fluid lactate levels and the pathomechanism of calcification in Fahr's disease by Hagiwara, N., Ooboshi, H., Ishibashi, M., Kurushima, H., Kitazono, T., Ibayashi, S., Iida, M.

“…In this study, we report the case of a 68‐year‐old man complaining of involuntary movement of his left shoulder and lower jaw plus dyspnea. On cranial computed…”
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NAD(P)H oxidase p22phox C242T polymorphism and ischemic stroke in Japan: the Fukuoka Stroke Registry and the Hisayama study by Kuroda, J., Kitazono, T., Ago, T., Ninomiya, T., Ooboshi, H., Kamouchi, M., Kumai, Y., Hagiwara, N., Yoshimura, S., Tamaki, K., Kusuda, K., Fujii, K., Nagao, T., Okada, Y., Toyoda, K., Nakane, H., Sugimori, H., Yamashita, Y., Wakugawa, Y., Asano, K., Tanizaki, Y., Kiyohara, Y., Ibayashi, S., Iida, M.

“…The C242T polymorphism of p22phox, a component of NAD(P)H oxidase, may have an impact on cardiovascular diseases; however, the association between this…”
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Altered vascular function after adenovirus-mediated overexpression of endothelial nitric oxide synthase by Ooboshi, H, Chu, Y, Rios, C D, Faraci, F M, Davidson, B L, Heistad, D D

“…Gene transfer with replication-deficient adenovirus is a potentially useful tool to study vascular biology. We have constructed a replication-deficient…”
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Intrapericardial administration of adenovirus for gene transfer by Lamping, K G, Rios, C D, Chun, J A, Ooboshi, H, Davidson, B L, Heistad, D D

“…Gene transfer to the heart has been accomplished with intravascular administration of adenoviral vectors into the pericardial sac, by increasing the duration…”
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Age-related vulnerability to cerebral ischemia in spontaneously hypertensive rats by YAO, H, SADOSHIMA, S, OOBOSHI, H, SATO, Y, UCHIMURA, H, FUJISHIMA, M

“…We sought to determine the effects of aging on regional cerebral blood flow and ischemic brain damage in transient cerebral ischemia in rats. Five adult (5-6…”
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Vascular expression of inducible nitric oxide synthase is associated with activation of Ca(++)-dependent K+ channels by Taguchi, H, Heistad, D D, Chu, Y, Rios, C D, Ooboshi, H, Faraci, F M

“…We tested the hypothesis that expression of inducible nitric oxide synthase (NO-synthase) in response to endotoxin (lipopolysaccharide) produces activation of…”
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Nox4 as the major catalytic component of an endothelial NAD(P)H oxidase by AGO, Tetsuro, KITAZONO, Takanari, OOBOSHI, Hiroaki, IYAMA, Teruaki, YOUN HEE HAN, TAKADA, Junichi, WAKISAKA, Masanori, IBAYASHI, Setsuro, UTSUMI, Hideo, LIDA, Mitsuo

“…Recent evidence has suggested that reactive oxygen species are important signaling molecules in vascular cells and play a pivotal role in the development of…”
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Postischemic gene transfer of interleukin-10 protects against both focal and global brain ischemia by OOBOSHI, Hiroaki, IBAYASHI, Setsuro, IIDA, Mitsuo, SHICHITA, Takashi, KUMAI, Yasuhiro, TAKADA, Junichi, AGO, Tetsuro, ARAKAWA, Shuji, SUGIMORI, Hiroshi, KAMOUCHI, Masahiro, KITAZONO, Takanari

“…Gene therapy may be a promising approach for treatment of brain ischemia, although the efficiency of postischemic gene therapy is not established. Our goal in…”
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NAD(P)H oxidases in rat basilar arterial endothelial cells by AGO, Tetsuro, KITAZONO, Takanari, IIDA, Mitsuo, KURODA, Junya, KUMAI, Yasuhiro, KAMOUCHI, Masahiro, OOBOSHI, Hiroaki, WAKISAKA, Masanori, KAWAHARA, Tsukasa, ROKUTAN, Kazuhito, IBAYASHI, Setsuro

“…Reactive oxygen species (ROS) may play a critical role in the regulation of vascular tone and development of vascular diseases, such as stroke. NAD(P)H oxidase…”
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YAG laser-induced reperfusion of photothrombotic middle cerebral artery occlusion in rats by Yao, H, Ibayashi, S, Sadanaga-Akiyoshi, F, Fukuda, K, Takada, J, Ooboshi, H, Kitazono, T, Uchimura, H, Fujishima, M

“…The laser-driven photochemical occlusion of middle cerebral artery(MCA) is much easier, and less traumatic than standard electrocautery or even clip methods,…”
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Cerebral blood flow and oxygen metabolism: estimation by PET; with special respect to ischemic cerebrovascular disorders (series 4) by Ooboshi, H, Fujishima, M

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A case of acute disseminated encephalomyelitis after renal transplantation by Iwanaga, T, Ooboshi, H, Imamura, T, Mizumasa, T, Ibayashi, S, Hirakata, H, Fujishima, M

“…We report a patient of acute disseminated encephalomyelitis (ADEM) in a recipient of renal transplantation. A 43-year-old man suffered from generalized…”
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Determination of guanine by high-performance liquid chromatography with electrochemical detection: application to DNA and RNA assays by Nakahara, T, Shiraishi, A, Hirano, M, Matsumoto, T, Kuroki, T, Tatebayashi, Y, Tsutsumi, T, Nishiyama, K, Ooboshi, H, Nakamura, K

“…A highly sensitive assay for guanine was developed using high-performance liquid chromatography with electrochemical detection (ECD). Guanine was susceptible…”
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Photothrombotic middle cerebral artery occlusion and reperfusion laser system in spontaneously hypertensive rats by YAO, Hiroshi, SUGIMORI, Hiroshi, FUKUDA, Kenji, TAKADA, Junichi, OOBOSHI, Hiroaki, KITAZONO, Takanari, IBAYASHI, Setsuro, IIDA, Mitsuo

“…To establish a less invasive and reproducible focal ischemia model in the rat, we adopted a 2-laser system (ie, photothrombosis and YAG laser-induced…”
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