Search Results - "Onwuzulike, Sophia"

TLR2 on CD4+ and CD8+ T cells promotes control of Mycobacterium tuberculosis infection by Reba, Scott M., Li, Qing, Onwuzulike, Sophia, Nagy, Nancy, Fletcher, Shane, Parker, Kyle, Shaw, Rachel J, Umphred‐Wilson, Katharine, Shukla, Supriya, Harding, Clifford V., Boom, W. Henry, Rojas, Roxana E.

“…Although a role for TLR2 on T cells has been indicated in prior studies, in vivo stimulation of TLR2 on T cells by Mtb and its impact on Mtb infection has not…”
Get full text

Macrophage Krüppel-like factor 4 regulates response to Mycobacterium tuberculosis infection by Mazahery, Claire, Chirieleison, Steven, Shukla, Supriya, Onwuzulike, Sophia, Jain, Mukesh, Boom, W Henry, Abbott, Derek W, Harding, Clifford V

“…Krüppel-like factor 4 (KLF4) is a transcription factor that polarizes macrophages towards an anti-inflammatory (M2) phenotype, which suggests that it may…”
Get full text

TLR2 engagement on CD4+ T cells enhances effector functions and protective responses to Mycobacterium tuberculosis by Reba, Scott M., Li, Qing, Onwuzulike, Sophia, Ding, Xuedong, Karim, Ahmad F., Hernandez, Yeritza, Fulton, Scott A., Harding, Clifford V., Lancioni, Christina L., Nagy, Nancy, Rodriguez, Myriam E., Wearsch, Pamela A., Rojas, Roxana E.

“…We have previously demonstrated that mycobacterial lipoproteins engage TLR2 on human CD4+ T cells and upregulate TCR‐triggered IFN‐γ secretion and cell…”
Get full text

TLR2 engagement on CD4 super(+) T cells enhances effector functions and protective responses to Mycobacterium tuberculosis by Reba, Scott M, Li, Qing, Onwuzulike, Sophia, Ding, Xuedong, Karim, Ahmad F, Hernandez, Yeritza, Fulton, Scott A, Harding, Clifford V, Lancioni, Christina L, Nagy, Nancy, Rodriguez, Myriam E, Wearsch, Pamela A, Rojas, Roxana E

“…We have previously demonstrated that mycobacterial lipoproteins engage TLR2 on human CD4 super(+) T cells and upregulate TCR-triggered IFN-[gamma] secretion…”
Get full text